髓外浆细胞瘤(extramedullary plasmacytoma,EMP)是一种原发于骨髓造血组织以外,单克隆浆细胞异常增生所致的软组织恶性肿瘤,占浆细胞肿瘤的3％～5％.EMP可发生于任何髓外组织器官,多见于头颈部或上呼吸道,其次为胃肠道,且以单发病灶为主,而原发于胆道的EMP临床罕见,尚未见报道,其临床症状及影像学检查结果与胆总管癌难以鉴别,易被误诊,诊断主要依靠病理检查.本文报告1例原发于胆总管的EMP,并结合文献,探讨此类疾病的治疗策略及转归.

目的：通过对临床病例资料进行分析，探讨华蟾素注射液单药对淋巴瘤的疗效。方法：回顾分析华蟾素注射液单药治疗2-3疗程的淋巴瘤患者，按照侵袭程度、初发/难治及中医辨证等分层，比较其疗效。结果：共21例合格患者，慢性淋巴细胞白血病5例，霍奇金淋巴瘤2例，弥漫大B细胞淋巴瘤7例，套细胞淋巴瘤2例，滤泡淋巴瘤2例，NK-T细胞淋巴瘤2例；其中惰性淋巴瘤的有效率（50%）和疾病控制率（100%）均高于侵袭性组（13.3%、53.3%），初发组的有效率（37.5%）高于复发组（13.4%），均有统计学差异(P<0.05),复发组的疾病控制率（69.2%）高于初发组（62.5%），无统计学意义(P>0.05)；气郁痰结组和阴虚痰瘀组的有效率分别为33.3%、42.9%，均高于寒痰凝结组、阴阳两虚组，有显著性差异(P<0.05)。结论：华蟾素注射液单药是治疗中晚期淋巴瘤的有效性药物，可能对惰性、初发、气郁痰结组和阴虚痰瘀淋巴瘤具有较好疗效，值得大样本的临床试验进一步验证。

近期我科收治2例血管免疫母细胞性T细胞淋巴瘤(AITL),在病程中并发了毛细血管渗漏综合征(capillary leak syndrome,CLS),现报告如下.

Objective In order to provide a large quantity of retinal pigment epithelial cells (RPE cells) in vitro, we want to estab-lish method for culturing pig RPE cells. Methods RPE cells were separated with trypsin and cultured in vitro. The cells were identified by immunohistochemical staining with anti-human keratin and transmission electron microscope (TEM). Results Cultured RPE cells gradually presented transparent and fusiform shape. Immunohistochemical staining demonstrated that the cells were stained by anti-human keratin, and the cultured cells showed typical ultrastructure of RPE cells. Conclusion The cultured cells may be the foundation of pig RPE cells.