Cardiotrophin-1 is an important factor that affects heart development during embryogen-esis. It plays an important role in varieties of cardiovascular diseases with it's wide range of biological effects such as inhibiting cardiomyocyte apoptosis,promoting cardiomyocyte hypertrophy and so on. Af-ter nearly 30 years of effort,it was found that cardiotrophin -1 played a significant role not only in the field of cardiovascular,but also in the system of respiratory,nervous,hematologic,et al.

室性心律失常可导致血流动力学紊乱、心脏性猝死等恶性事件,已是医学界公认的事实,其复杂的发病机制、快速的病情进展、较高的病死率至今困扰临床医师。近年来,植入型心脏复律除颤器、射频消融术的应用已为许多患者带去福音,然而受技术水平、经济条件等诸多因素的限制,这些治疗手段在许多基层医院都无法实施。寻找一种操作简单、费用低、风险小、能够广泛开展的方法依然是医学工作者努力的方向。