目的:探讨大黄素对大鼠肾间质纤维化模型中骨形态发生蛋白-7(BMP-7)表达的影响及意义.方法:清洁级Wister雄性成年大鼠160只随机分为四组:正常对照组、假手术组、模型组及大黄素治疗组.制备单侧输尿管梗阻(UUO)模型[1];治疗组在UUO的基础上每天以大黄素40 mg/kg灌胃,分别在术后1 d、3 d、7 d、14 d,每组取10只大鼠处死,取左侧肾脏行免疫组织化学方法检测肾组织中BMP-7的表达水平,动态观察BMP-7在各组大鼠术后梗阻侧肾脏1 d、3 d、7 d、14 d的组织学变化及大黄素对其影响.结果:模型组BMP-7的表达持续减少;治疗组BMP-7的表达水平高于模型组(P<0.01).结论:中药大黄素可以通过促进BMP-7的表达来发挥其延缓肾间质纤维化进程的作用,对肾纤维化有治疗作用.

Objective:To discuss the curative effect of EMG biofeedback treatment to child tic disorder.Methods:40 EMG biofeedback treatments were applied to children with tic disorder received by pediatrics departments from October 2009 to December 2011 and therapeutic evaluation with TSGS was made before and after the treatments. Result:Among children with EMG biofeedback treatment, 17cases were effective, 4 cases got bet er, 2 cases were of no effects, the total effective rate was 91.3%. Conclusion:EMG biofeedback treatment is an egective method to cure child tic disorder.

目的探讨新生儿桡静脉与头皮静脉采集血标本的临床应用价值。方法 156例新生儿随机分为实验组和对照组。观察组(A组)用桡静脉采集血标本;对照组(B组)采用头皮静脉采集血标本。结果通过桡静脉采集血标本,静脉粗,只要定位准确,穿刺成功率高,采血符合验血需要。通过头皮静脉采集血标本,静脉浅表、易见,容易穿刺,但静脉较细,采血量不符合检验需要,影响穿刺成功率。结论新生儿静脉穿刺采集血标本优于头皮静脉,定位准确,穿刺成功率高,符合检验标准,在临床上值得提倡。