Objective:To observe the clinical effects of Robot System Assistant (Rosa) localized burr hole hematoma removal and empirical localized burr hole hematoma removal in the treatment of spontaneous intracerebral hemorrhage (SICH).Methods:A total of 100 patients with SICH who were admitted to Neurosurgery Department of Gezhouba Central Hospital of Sinopharm between February 2017 and January 2019 were selected as the subjects. They were divided into the observation group (41 cases) and the control group (59 cases) according to the voluntary and non-randomized control principle. Patients in the observation group were treated with Rosa localized burr hole hematoma removal, and those in the control group were treated with empirical localized burr hole hematoma removal. Surgery related indicators of the two groups were recorded. The short-term and long-term curative effects and the occurrence of postoperative complications were compared between the two groups.Results:Compared with the control group, the operation time, hematoma removal time and postoperative hospital stay in the observation group were significantly shorter, the incidence rate of postoperative complications in the observation group was significantly reduced (P<0.05). At 1 month after surgery, the effective rate of treatment in the observation group was higher than that in the control group (P<0.05). There was no statistically significant difference in the good prognosis rate between the two groups at 6 months after surgery (P>0.05).Conclusion:Rosa localized burr hole hematoma removal has the same long-term effect as empirical localized burr hole hematoma removal in the treatment of SICH. However, the former can achieve better short-term effect, faster postoperative recovery and lower risk of complications, with characteristics of safety, efficiency and accuracy.

目的 探讨在颅脑损伤患者护理中引入基于莱温守恒模式干预效果.方法 选取2019年6月至2021年6月在国药葛洲坝中心医院诊治的100例颅脑损伤患者采用随机数字表法进行分组.常规组(50例)行常规护理,干预组(50例)再行基于莱温守恒模式干预.观察干预2周后,比较患者自我管理能力、神经功能改善及住院期间并发症发生情况.结果 干预后,干预组疾病、情绪、生活、康复锻炼、社会与人际管理评分高于干预前,且高于常规组,差异有统计学意义(P＜0.05).干预后,两组改良Rankin量表及美国国立卫生研究院卒中量表评分低于干预前,且干预组低于常规组,差异有统计学意义(P＜0.05).干预组并发症总发生率低于常规组,差异有统计学意义(P＜0.05).结论 莱温守恒模式下护理用于颅脑损伤患者,可提高患者自我管理能力及神经功能恢复效果,减少并发症.

目的:研究开颅术后脑积水行脑室腹腔分流术后的护理干预措施及其实践效果.方法:以2014年5月至2017年5月在我院采用脑室腹腔分流术治疗60例开颅术后脑积水疾病患者为观察对象,随机分成实验组(30例)、对照组(30例),分别于分流术后行优质护理、常规护理,对比两种护理方法实践效果.结果:对照组脑积水患者分流术后并发症总体发生概率(13.33％)高于实验组(0.00％),差异有统计学意义(P<0.05).结论:优质的术后对症护理支持有利于避免脑室腹腔分流术后开颅术后脑积水临床住院患者发生并发症.

Objective To study the effect of resveratrol on glioma cell line U251 in vitro and its potential regu-latory mechanism.Methods U251 cells in logarithmic growth phase were divided into the blank control group and dif-ferent doses of(25 mol/L,50 mol/L,100 mol/L)resveratrol groups.MTT colorimetric method was used to evaluate the effects of resveratrol on proliferation rate of U251 cells;the effect of resveratrol on apoptosis of U251 cells were detect-ed by flow cytometry;reverse transcriptase polymerase chain reaction(RT-PCR)and Western blot were used to detect the effect of resveratrol on the mRNA and protein expression levels of U251 cells on Wnt,β-catenin,p53,p21,Bcl-2 and Bax,respectively.Results After resveratrol treating U251 cells for 72 h,the results of MTT showed that U251 cell proliferation rate of the blank control group was(94±5)%,and the U251 cell proliferation rates of the different doses of resveratrol groups were(64±4)%,(43±4)% and(27±2)%,respectively.Compared with the blank control group,the cell proliferation rates of the resveratrol groups were significantly decreased,and there were statistical significance between the different doses of resveratrol groups and the blank control group(P<0.05);the results of flow cytometry showed that the apoptosis rate of U251 cells in the blank control group was(4±1)%,and the apoptosis rate of U251 cells in the differ-ent doses of resveratrol groups were(25±2)%,(55±3)% and(72±5)%,respectively.The apoptosis rates of the different doses of resveratrol groups were significantly higher than that in the blank control group,and there were statistically sig-nificant differences between the different doses of resveratrol group and the blank control group(P<0.05);RT-PCR and Western blott showed that,compared with the blank control group,the different doses of resveratrol groups had lower ex-pression of Wnt,β-catenin,p53,p21 and Bcl-2 in U251 cells and higher expression of Bax(P<0.05).Conclusion Res-veratrol can induce the proliferation inhibition and apoptosis of human glioma cells lines U251,which is associated with suppressing Wnt/β-catenin/p53 signal pathway.

目的:探索在神经外科患者护理的交接班当中,SBAR沟通模式的具体应用效果.方法:选择我院在2016年1—12月期间神经外科收治的102例患者为主要对象,将所有患者按照其护理交接班的不同方式均匀分成常规组与沟通组,常规组患者的护理人员按照正常模式交接班,沟通组患者护理人员则采用SBAR模式进行交接班,对比两组不同交接班模式干预下患者的护理不良事件发生情况.结果:沟通组患者出现不良事件的例数明显少于常规组,双方患者的具体数据比较后存在显著差异(P<0.05).结论:在神经外科护理交接班工作当中,SBAR沟通模式有较好的应用效果,值得推广.

目的：分析在老年骨质疏松性肱骨近端骨折患者的临床治疗中，手术治疗与非手术治疗的不同效果。方法选取我院2015年1月～2016年1月收治的70例老年骨质疏松性肱骨近端骨折患者为研究对象，将其随机分为对照组与干预组，对照组患者接受非手术治疗，干预组患者则接受手术治疗，对比两组患者的治疗效果及并发症发生情况。结果干预组患者的治疗效果要明显好于对照组患者，且并发症例数少于对照组患者，差异有统计学意义（P＜0.05）。结论在老年骨质疏松性肱骨近端骨折患者的临床治疗中，医生需要根据患者的具体骨折情况为其选择对应的治疗方法，以此保证患者的治疗效果。

目的：本文将针对在受到颅脑外伤并接受手术之后患者发生颅骨缺损症状同时伴有脑积水的症状做以诊治分析，并总结经验。方法选取2015年4月～2016年4月我院收治的颅脑外伤患者36例作为研究对象，随机将其分成实验组和参照组，各18例。对参照组行以脑室-腹腔分流手术同颅骨修复术分期干预；对实验组行以脑室-腹腔分流手术同颅骨修补手术一期联合干预。对照分析两组患者最终疗效，做以总结和记录。结果经过不同的治疗干预，实验组的整体有效率明显好于参照组，差异有统计学意义（P＜0.05）。结论针对受到颅脑外伤接受手术之后患者发生颅骨缺损症状同时伴有脑积水的症状的患者，行以脑室-腹腔分流手术同颅骨修补手术一期联合干预的方式，能够获得非常理想的疗效，值得进行更加深入的分析和推广。