Objective To investigate the medication rule of Professor Liang Xiaochun in the treatment of diabetic microvas-cular complications.Methods A retrospective real-world study method was used,with the electronic medical records from the hospital information system of Peking Union Medical College Hospital as the carrier.Clinical information of patients treated for diabetic microvascular complications by Professor Liang Xiaochun from January 2021 to December 2022 was col-lected to construct a database,which was then entered into the Traditional Chinese Medicine Inheritance Platform(V 3.5).Techniques such as association rule mining and cluster analysis were used to analyze the frequency of medication usage,the nature,flavour,and channel tropism of the medicines,and common drug combinations,the treatment principles and medica-tion patterns of Professor Liang Xiaochun for diabetic microvascular complications were summarized.Results A total of 301 effective prescriptions for treating diabetic microvascular complications by Professor Liang Xiaochun were collated,involving 211 Chinese herbal medicines.The most frequently used medicines were Mori Cortex,Cuscutae Semen,Commelina com-munis,Fructus Ligustri Lucidi,Euonymus alatus,Achyranthes aspera,etc.The four natures were mostly cold,and the five flavours were mostly sweetness.The channel tropism belonged to the liver,spleen,and kidney.The core combinations of medicines identified through correlation analysis were Cuscutae Semen-Fructus Ligustri Lucidi,Cuscutae Semen-Achyranthes aspera,Cuscutae Semen-Commelina communis,Cuscutae Semen-Mori Cortex,Fructus Ligustri Lucidi-Achyranthes aspera,Achyranthes asp era-Smilacis Glabrae Rhixoma,Fructus Ligustri Lucidi-Mori Cortex,Fructus Ligustri Lucidi-Commelina communis.The four core prescrip-tions were obtained by cluster analysis:Fructus Ligustri Luci-di-Cuscutae Semen-Mori Cortex-Commelina communis-Eu-onymus alatus-Achyranthes aspera,Commelina communis-Mori Cortex-Radix Puerariae-Salvia miltiorrhiza-Cuscutae Semen-Fructus Ligustri Lucidi,Fructus Ligustri Luci-di-Commelina communis-Cuscutae Semen-Mori Cortex-Chuanxiong Rhizoma-Spatholobus Suberectus Dunn,Mori Cor-tex-Cuscutae Semen-Folium Nelumbinis-Commelina communis-Fructus Ligustri Lucidi-Chuanxiong Rhizoma.Conclu-sion Professor Liang Xiaochun treats diabetic microvascular complications with the main therapeutic principles of invigorat-ing blood circulation to remove blood stasis,clearing away phlegm to eliminate turbidity,and supplementing deficiencies to support the body's vital energy.
Abstract Background Older patients (aged ≥ 60 years) with severe brain injury have a high mortality and disability rate. The objective of this retrospective study was to assess the clinical risk factors of prognosis in older patients with severe brain injury after surgical intervention and to analyze the prognosis of the surviving group of patients 1 year after discharge. Methods Clinical data of older patients with severe brain injury who were admitted to two neurosurgical centers between January 2010 and December 2020 were collected. Patient age, sex, Glasgow Coma Scale (GCS) score at admission, underlying disease, mechanisms of injury, abnormal pupillary reflex, head computed tomography imaging findings (such as hematoma type),intraoperative brain swelling and other factors were reviewed. All the patients were categorized into a good prognosis (survival) group and a poor prognosis (death) group by the Glasgow Outcome Score (GOS); also, the related factors affecting the prognosis were screened and the independent risk factors were identified by the Binary logistic regression analysis. GOS was used to evaluate the prognosis of the surviving group of patients 1 year after discharge. Results Out of 269 patients, 171 (63.6%) survived, and 98 (36.4%) died during hospitalization. Univariate analysis showed that age, GCS score at admission, underlying diseases, abnormal pupillary reflex, the disappearance of ambient cistern, the midline structure shift, intraoperative brain swelling, oxygen saturation < 90%, and cerebral hernia were risk factors for the prognosis of older patients with severe brain injury after surgical intervention. Multivariate analysis showed that age, underlying diseases, disappearance of ambient cistern, Oxygen saturation < 90% and intraoperative brain swelling were independent risk factors of the prognosis in the population. The effect of surgical intervention differed among various age groups at 1-year follow-up after surgery. Conclusions The results of this retrospective study confirmed that age, underlying diseases, disappearance of ambient cistern, intraoperative brain swelling, and oxygen saturation < 90% are associated with poor prognosis in older postoperative patients with severe brain injury. Surgical intervention may improve prognosis and reduce mortality in older patients (age < 75 years). But for those patients (age ≥ 75 years), the prognosis was poor after surgical intervention.
Objective To investigate the risk factors of colorectal polyps＜10 mm in diameter with high-risk adenoma.Methods Patients who underwent colonoscopy in the First Medical Center of Chinese People's Liberation Army General Hospital and Hainan Hospital of Chinese People's Liberation Army General Hospital from October 2019 to March 2021 were selected as study objects.According to the number of adenomas and pathological features,the patients were divided into high-risk adenoma group and non-high-risk adenoma group.The risk factors of high-risk adenoma were analyzed.Results A total of 1 267 patients were included in the study,including 341 patients(26.9％)in the high-risk adenoma group and 926 patients(73.1％)in non-high-risk adenoma group.The proportion of age(45-＜75 years old),male,drinking history,smoking history,frequent consumption of pickled food,high salt diet,chronic history,history of colorectal polyp,and maximum polyp diameter(＞5-＜10 mm)in high-risk adenoma group was higher than those in non-high-risk adenoma group(P＜0.05).Age(45-＜75 years),male,high salt diet,occasional anal distention,chronic history,and maximum polyp diameter(＞5-＜10 mm)were risk factors for high-risk adenomas(OR＞1,P＜0.05).Conclusion Age(45-＜75 years),male,high salt diet,occasiontal anal distention,chronic history,and maximum polyp diameter(＞5-＜10 mm)are risk factors for colorectal polyps＜10 mm with high-risk adenomas,providing a basis for endoscopists to assess the risk and apply targeted"resect and discard strategy".
目的 基于VOSviewer对当下媒体与心理交叉领域的研究进展进行计量分析.方法 在Scopus上收集2018年 1 月至 2022 年 6 月所有媒体与心理交叉领域的文献,筛选后基于VOSviewer从作者和关键词两个角度进行连接强度、时间、词团聚块等维度上的计量分析.结果 筛选得 3 233 篇文献,发现 2022 年 2 月研究主体由Griffiths MD为核心的学者集团转移到以Li为核心的中国学者团,中国学者间总体连接数大、但个体连接强度较弱,总发文量大、但单篇被引量较低;40%的作者关键词聚焦于受媒体影响的大众心理健康状态;存在以性别和年龄阶段命名的词团聚块;信息流行病学被广泛提及.结论 国内学界对于该领域的研究基础规模大但影响力还需提升;受媒体影响产生的抑郁与焦虑及所属的心理健康大类是目前的主流研究方向;二分性别和年龄是当下主要使用的人群分类研究方式;信息流行病学有潜力作为新兴学科进一步发展.
目的 基于p38 丝裂原活化蛋白激酶(p38MAPK)通路探讨瑶医除闷汤药浴治疗膝骨关节炎(KOA)模型大鼠的效果与作用机制.方法 在 60 只 8 周龄雄性SPF级SD大鼠(体重 200～220 g)中随机选取 10 只作为空白组,在实验第 1、4 天,于空白组右膝关节腔内注射 0.1 ml生理盐水,其余大鼠注射 0.1 mlⅡ型胶原蛋白酶与弗氏完全佐剂的混合乳剂(质量浓度为0.5 mg/ml).第 7天根据大鼠膝关节情况评估造模结果,将 50只造模成功的大鼠按照随机数字表法分为模型组、双氯芬酸钠组及除闷汤高、中、低剂量组,每组 10 只.实验第 8 天,对除闷汤高、中、低剂量组进行药浴干预(浓度分别为 49.00、24.50、12.25 g/L),模型组进行温水泡浴,双氯芬酸钠组于造模部位予 0.01 g的 1%双氯芬酸钠凝胶,空白组常规饲养,连续干预 4周,干预期间观察各组一般情况.干预后观察各组膝关节解剖学情况,测量膝关节直径,采用苏木精-伊红(HE)染色观察膝关节软骨组织形态学改变.采用酶联免疫吸附试验检测各组血清中白细胞介素-1β(IL-1β)、IL-6、IL-10 含量;采用免疫组织化学染色检测各组软骨组织中p38MAPK、磷酸化p38MAPK(p-p38MAPK)、基质金属蛋白酶-13(MMP-13)的表达水平.结果 药物干预期间,空白组一般情况正常;模型组强迫运动时跛行,伴膝关节屈伸功能障碍;除闷汤各剂量组膝关节屈伸功能与步态逐渐恢复,双足跛行状态减少.干预后,空白组膝关节解剖可见滑膜平滑半透明,软骨透明光滑,关节面完整,HE染色可见软骨细胞排列规则清晰;模型组膝关节解剖可见滑膜增厚糜烂,软骨表面粗糙磨损,色泽灰暗,HE染色可见软骨基质减少甚至消失,软骨细胞大量减少,形态不规则;除闷汤各剂量组膝关节解剖及HE染色可见膝关节软骨有不同程度改善.模型组膝关节直径大于空白组,血清IL-1β、IL-6 及软骨p38MAPK、p-p38MAPK、MMP-13表达均高于空白组,血清IL-10低于对照组(P＜0.05).除闷汤各剂量组膝关节直径小于模型组,血清IL-10高于模型组,软骨p-p38MAPK、MMP-13表达均低于模型组(P＜0.05).除闷汤高、中剂量组血清IL-1β、IL-6及软骨p38MAPK低于模型组和除闷汤低剂量组,IL-10高于除闷汤低剂量组(P＜0.05).除闷汤高剂量组膝关节直径小于除闷汤低、中剂量组,软骨p-p38MAPK、MMP-13 表达低于除闷汤低剂量组,血清IL-10高于除闷汤低、中剂量组,软骨MMP-13 表达低于除闷汤中剂量组(P＜0.05).结论 瑶医除闷汤可能通过靶向抑制p38MAPK通路表达,减轻KOA大鼠的炎症反应,改善软骨退变.
目的 探讨创伤大出血伴严重凝血功能障碍患者血栓弹力图指导输血的应用.方法 选取 2018 年 12 月至2021年12月江苏省连云港市第二人民医院接诊的 107 例创伤大出血伴严重凝血功能障碍患者,采用随机数字表法分为常规组(54例,常规凝血功能检测)和研究组(53 例,血栓弹力图检测).统计输血前后活化部分凝血酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)和纤维蛋白原(FIB).统计输血过程中血小板、血浆、红悬液、冷沉淀的用量.统计住院时间与ICU治疗时间和住院期间并发症的发生情况.结果 输血后,两组APTT、PT、TT短于输血前,且研究组短于常规组;两组FIB高于输血前,且研究组高于常规组,差异有统计学意义(P＜0.05).研究组血小板、血浆、红悬液、冷沉淀的用量少于常规组,差异有统计学意义(P＜0.05).两组住院时间比较,差异无统计学意义(P＞0.05).研究组ICU入住时间短于常规组,差异有统计学意义(P＜0.05).两组并发症总发生率比较,差异无统计学意义(P＞0.05).结论 血栓弹力图检查在指导创伤大出血伴严重凝血功能障碍患者输血中具有一定指导价值.
目的 采用高通量测序技术对稽留流产绒毛组织遗传因素进行分析.方法 回顾性分析 2017 年 6 月至2020年 6月清华大学第一附属医院因稽留流产行清宫手术的 91例患者,对稽留流产绒毛组织进行高通量测序分析,分析绒毛染色体数目改变和拷贝数变异情况.结果 91 例稽留流产绒毛组织均进行高通量测序,70 例(76.08%)染色体异常,其中染色体数目异常 39 例、嵌合体 5 例、拷贝数变异 26 例.拷贝数变异中微重复 14例、微缺失 6 例、混合型 6例.结论 胚胎染色体异常是稽留流产的主要原因,以非整倍体为主,高通量测序技术拷贝数变异应用于绒毛染色体检测,具有较高敏感性,可增加染色体异常检出率,有助于明确稽留流产病因.
随着泌尿系统疾病的发病率逐年上升,如何有效治疗此类疾病成为临床研究和药物研究的重要课题.以抗生素为代表的传统西药,虽起效快,但容易产生多种副作用.银花泌炎灵成分天然,现代科学研究证明其具有良好的抗菌、利尿、抗炎的功效,在泌尿系统疾病的治疗中展现出优秀的效果及安全性,被广泛应用.本文将从基础研究层面阐述银花泌炎灵的作用机制,从临床研究层面总结银花泌炎灵治疗泌尿系统疾病的效果及优势;分析当前存在的问题,指出今后的研究方向,以期为临床治疗提供更为有效和安全的药物选择.
目的 探究急性中度呼吸衰竭经鼻高流量氧疗(HFNC)治疗失败患者的影响因素.方法 收集2021年1月至2021年9月江苏省常熟市第一人民医院收治的80例急性中度呼吸衰竭患者作为研究对象,按照是否转为无创或气管插管分为HFNC成功组(43例)和HFNC失败组(37例).比较两组一般资料、预后、呼吸循环指标和肺部超声指标,并分析相应影响因素.结果 HFNC成功组肺部超声评分(LUS)低于HFNC失败组,膈肌活动度(DE)高于HFNC失败组,差异有统计学意义(P＜0.05).HFNC成功组呼吸频率(RR)、平均动脉压(MAP)水平低于HFNC失败组,心率(HR)、ROX指数高于HFNC失败组,差异有统计学意义(P＜0.05).logistic回归分析结果显示,RR、MAP、LUS升高是HFNC治疗失败的独立危险因素(OR＞1,P＜0.05);DE、HR、ROX指数升高是HFNC治疗失败的保护因素(OR＜1,P＜0.05).结论 HFNC治疗失败的患者的肺部超声、呼吸循环相关指标较差,RR、MAP、LUS升高是HFNC治疗失败的危险因素,DE、HR、ROX指数升高是保护因素.
目的 比较腹腔镜下完全腹膜外疝修补术(TEP)与经腹腔腹膜前疝修补术(TAPP)治疗成人单侧初发腹股沟疝的临床效果.方法 选取 2019年5月至 2021年 6月江苏省太仓市中医医院收治的 82例单侧初发腹股沟疝患者为研究对象,采用随机数字表法将其分为TEP组(给予TEP治疗)和TAPP组(给予TAPP治疗),每组 41例.比较两组手术相关指标、住院费用、血气变化指标[手术前后动脉血二氧化碳分压差值(ΔPaCO2)、术中经皮二氧化碳分压监测(TcCO2)最大值与术前TcCO2 的差值(ΔTcCO2)、达到TcCO2 最大值的时间(Tmax)]、术后疼痛情况、术后并发症及术后6个月复发情况.结果 TEP组手术时间、Tmax短于TAPP组,住院费用低于TAPP组,ΔPaCO2、ΔTcCO2 均高于TAPP组,差异有统计学意义(P＜0.05).两组术中失血量、住院时间、疼痛持续时间、术后 24h视觉模拟评分法评分、术后并发症总发生率、术后 6 个月复发率比较,差异无统计学意义(P＞0.05).结论 成人单侧初发腹股沟疝采用TEP在手术时间、住院费用方面优于TAPP,在减少手术中体内二氧化碳方面TAPP具有优势,两种手术方式治疗成人单侧初发腹股沟疝术后疼痛情况相近,且均安全、有效.
目的 探讨低频重复经颅磁刺激对脑卒中偏瘫患者下肢痉挛及平衡步态的影响.方法 选取2021年4月至2022年4月中国医科大学第一附属医院收治的176例脑卒中偏瘫患者,采用随机数字表法将其分为对照组、观察组,各88例.对照组以常规康复+核心肌力训练干预,观察组在对照组的基础上增加低频重复经颅磁刺激.2周为1个疗程,两组均连续治疗3个疗程.比较两组临床疗效及治疗前后的症状评分、平衡步态参数,评价治疗安全性.结果 观察组临床疗效优于对照组(P＜0.05).治疗后,两组临床痉挛指数(CSI)均低于治疗前,Berg平衡量表(BBS)、Fugl-Meyer运动功能量表下肢评估(FMA-LE)评分均高于治疗前,且观察组CSI低于对照组,BBS、FMA-LE评分高于对照组(P＜0.05).治疗后,两组屈髋峰值、屈膝峰值、步幅、步频、步速均高于治疗前,且观察组高于对照组(P＜0.05).治疗期间两组不良反应总发生率比较,差异无统计学意义(P＞0.05).结论 低频重复经颅磁刺激对脑卒中偏瘫下肢痉挛的治疗效果良好,能提高患者下肢功能、平衡功能和步行功能,且安全性较好.
目的 探讨小剂量吗啡椎管内镇痛在老年患者下肢骨科手术中的应用效果及对术后认知功能障碍(POCD)发生的影响.方法 选取2020年7月至2021年7月江苏省张家港市第二人民医院收治的82例拟行手术治疗的老年下肢骨折患者,依据随机数字表法将其分为对照组(41例)和研究组(41例).两组均实施腰硬联合麻醉,手术结束后,研究组于硬膜外腔注入1.5 mg吗啡.比较两组手术时间及右美托咪定术中、术后使用量;比较两组术后1、2周POCD发生率;比较两组术前及术后1周简易智力状态检查量表(MMSE)评分;比较两组术前及术后6、48h视觉模拟评分法(VAS)评分;观察两组不良反应发生情况.结果 两组手术时间及右美托咪定术中、术后使用量比较,差异无统计学意义(P＞0.05).两组组内不同时间点VAS评分比较,差异有统计学意义(P＜0.05);术后6、48 h,研究组VAS评分低于对照组,差异有统计学意义(P＜0.05).术后1、2周,研究组POCD发生率低于对照组,差异有统计学意义(P＜0.05).术后1周,两组MMSE评分低于术前,研究组高于对照组,差异有统计学意义(P＜0.05).两组不良反应总发生率比较,差异无统计学意义(P＞0.05).结论 小剂量吗啡椎管内镇痛应用于老年患者下肢骨科手术,可减少右美托咪定术中、术后使用量,降低POCD发生率,改善认知功能,缓解疼痛.
Objective To observe application effect of EEG combined with EMG biofeedback training combined with resistance training in the treatment of spastic cerebral palsy（SCP）. Methods A prospective randomized controlled trial was conducted in this study, 107 children with SCP who were admitted to Aviation General Hospital of China Medical University from July 2015 to July 2021 were selected. They were divided into observation group（54 cases） and control group（53 cases）by random number table method. Control group received routine rehabilitation training+EEG combined with EMG biofeedback training, while observation group combined with resistance training on the basis of control group, the intervention lasted for three months. The gross motor function measure（GMFM） score, gastrocnemius and soleus modified ashworth scale（MAS） scores, 6, 10 min walking test, and physiological consumption index（PCI） were compared between two groups before intervention and three months after intervention. Results Three months after intervention, GMFM scores were higher in both groups than those before intervention, and observation group was higher than control group, with astatistical significant differences（P＜0.05）; MAS scores of gastrocnemius and soleus were lower than those before intervention, and observation group was lower than control group, with statistical significant differences（P＜0.05）; the 6, 10 min walking tests in both groups were higher than those before intervention, and PCI was lower than that before intervention, and the 6,10 min walking tests in observation group were higher than those in control group, PCI was lower than that in control group, with statistical significant differences（P＜0.05）. Conclusion EEG combined with EMG biofeedback training combined with resistance training can more effectively improve children’s SCP motor function and muscle tension, significantly improve their walking endurance, and reduce energy consumption during exercise.
目的 了解北京市医院内镜室清洗消毒现状.方法 于2021年3月至8月采用方便抽样的问卷调查方法,对北京市42所三级医院内镜中心(室)的布局设施、制度建设、培训、职业安全防护、清洗消毒(灭菌)流程、监测和记录等全流程进行调查.结果 回收调查问卷42份,有效回收率为100％.42所医院中,10所机构没有配备办公用房,12所机构没有设置麻醉恢复室,6所机构应急预案的制订欠缺,培训还存在较大的差距.清洗消毒槽全部配备,动力泵、超声波清洗器的配备分别是76.2％和 69.0％,内镜自动清洗机73.8％配置.环氧乙烷、低温甲醛、过氧化氢低温等离子灭菌器分别有30.9％、9.5％和 59.5％的医院配备.消毒剂邻苯二甲醛59.5％医院使用,40.5％医院使用复方含氯消毒剂.42所医院都为消毒人员提供了防护用品.15所医院(35.7％)消毒室采用自然通风,27所医院(64.3％)安装了机械通风,安装的位置有5所(18.5％)在天花板,不符合规范的要求.在内镜用后的预处理、测漏等要求上还有一定的差距.结论 所有医疗机构能够遵循规范清洗消毒的基本要求.但在设施设备的配置,清洗消毒细节的落实上还存在一定的差距.医疗机构要对照新规范不断改进,降低医院感染发生.
静脉血栓栓塞症(VTE)已成为全球第三大血管疾病,筛选出相关危险因素,进而筛查出高危人群是临床工作中的关键.现已经有多种VTE风险评估模型(RAM)用于临床实践,Caprini RAM主要用于外科,Padua预测评分主要用于内科,而Khorana RAM主要用于肿瘤患者.在不同的临床应用场景中,这些模型仍有一定的局限性,因此设计出个性化的预测模型已成为研究的主要方向.本文旨在对经典的VTE风险评估模型及其在临床应用中的进展进行综述.
颈源性头痛(CEH)是一种源于颈部结构的继发性头痛,其发病机制存在争议,诊断上缺少如影像学的客观诊断标准,误诊率高,治疗方案的选择存在主观差异.研究发现,CEH主要由生理曲度、关节结构、颈部肌群、筋膜韧带及硬脑膜等结构异常引起的疼痛.物理疗法在CEH临床应用最广,物理疗法(手法治疗、运动疗法、针刺等)可通过多靶点作用改善CEH患者的症状、颈椎活动度、生活质量、炎症指标等.本文就CEH的病因、物理疗法的治疗进展做一综述,以期为今后CEH的研究提供参考.
Objective To analyze Professor Liu Yanqiao's prescription medication rules in the treatment of polycystic ovary syndrome(PCOS)based on data mining analysis.Methods The PCOS medical cases treated by Professor Liu Yanqiao from the Second Affiliated Hospital of Xi'an Jiaotong University from October 2019 to February 2023 were screened,and input into Excel to establish a database,prescription drug frequency,efficacy classification,flavor and meridian tropism were counted;R language and SPSS Statistics software were used for association rules and cluster analysis.Results A total of 131 prescriptions were collected,including 115 flavors of traditional Chinese medicine,and 20 flavors were used more than 40 times,the highest frequency was Shanyao and Xiangfu 90 times,most of which belonged to tonifying deficiency drugs and promoting blood circulation and removing blood stasis drugs,with sweet and bitter tastes,mainly warm and cold drugs,and most of them were attributed to liver(gallbladder)channel.Association rule analysis showed that there were 13 common drug pairs,and the support of angelica-Chuanxiong was the highest,and there were 13 kinds of three kinds of medicine combination,and the support of Xiangfu-angelica-Chuanxiong was the highest.Based on cluster analysis,three groups of cluster prescriptions were obtained,corresponding to kidney deficiency and blood stasis type,phlegm stasis block type,and spleen deficiency and phlegm dampness type respectively.Conclusion In the treatment of PCOS,Professor Liu Yanqiao combines with promoting blood circulation and resolving stasis,dispelling dampness and resolving phlegm,etc.on the basis of tonifying the kidney,strengthening the spleen,and soothing the liver,in order to comply with the physiological process of follicle growth,development,and excretion.
Objective To provide a theoretical basis and decision-making reference for formulating,implementing,and adjusting policies of evaluation study of health financial policy.Methods This study used a policy modeling consistency(PMC)index model to conduct an empirical study of 15 selected health financial policies at the central level.Results Based on text mining,content analysis,expert argumentation,and relevant policy research results,this study constructed a PMC index model consisting of nine primary indicators and 40 secondary indicators.The empirical study found that the evaluation results of health financial policies were generally good,including 10 excellent and five qualified.Conclusion The health financial policies of China take into account various elements needed in the policy formulation process,including a rich variety of policy types,the use of multiple policy tools,and a high degree of policy standardization.However,there is still room for optimization.Therefore,this study puts forward relevant recommendations for the subsequent development and implementation of policies in China to be more scientific and effective.
Objective To develop a scientific and feasible self-reported outcome scale for patients with cervical spondylotic radiculopathy and test its reliability and validity.Methods The concept structure was defined based on the theory of dyspeptic symptoms,the item pool was constructed through literature review and semi-structured interview,and the initial scale was formed after two rounds of expert correspondence.From October 2021 to June 2022,a total of 172 patients with cervical spondylotic radiculopathy were conveniently selected for formal investigation to test the reliability and validity of the scale.Results There were 24 items in three dimensions in the self-reported outcome scale of cervical spondylotic radiculopathy patients.Three common factors were extracted by exploratory factor analysis,and the cumulative variance contribution rate was 61.380%.The content validity of the items was 0.812-1.000,and the content validity of the scale was 0.964.The Cronbach's α coefficient of the total volume table was 0.890,and the retest reliability was 0.832.Conclusion The self-reported outcome scale of cervical spondylotic radiculopathy patients has good reliability and validity,and can provide reference for the evaluation tool of this population.
Objective To observe the clinical effect of acupoint stimulation combined with breast massage on improving postpartum breast deficiency in caesarean section parturients.Methods From January 2019 to December 2020,150 parturients who received caesarean section delivery in the Department of Obstetrics,Zibo First Hospital of were included in the study.According to the random number table method,they were divided into the observation group and the control group,with 75 cases in each group.The control group adopted routine postpartum care,while the observation group adopted acupoint stimulation combined with breast massage on the basis of the control group.The scores of milk secretion,traditional Chinese medicine score,and serum prolactin level were compared between the two groups before and after nursing.Neonatal breastfeeding rates and Newcastle nursing satisfaction scale(N SNS)scores were compared between the two groups after discharge.Results Intra-group comparison:there was statistical significance in the score of milk secretion between the two groups at each time point(P＜0.05).Inter-group comparison:one,two and three days after intervention,the scores of maternal milk secretion in observation group were higher than those in control group(P＜0.05).The scores of breast filling degree,milk siltation degree,and milk viscosity degree in two groups were lower than before intervention,and those in the observation group were lower than control group(P＜0.05).After discharge,the neonatal breastfeeding rate in the observation group was higher than that in the control group(P＜0.05).After intervention,the maternal NSNS score in observation group was higher than that in control group(P＜0.05).Conclusion Acupoint stimulation combined with breast massage can effectively improve the symptoms of breast deficiency of parturients after cesarean section,improve their breast filling and viscosity,reduce the degree of milk stasis,and improve the rate of breast feeding of newborns.
