目的:了解重症急性胰腺炎的病因、药物治疗方案的设计以及药学监护计划的实施.方法:对1例患者的发病原因、药物治疗方案的选择、药学监护计划的实施以及用药指导进行分析.结果:发现对重症急性胰腺炎患者抗感染治疗应采取广覆盖、降阶梯的治疗原则.结论:临床药师参与重症患者的药物治疗方案设计有积极地作用.

目的:了解重症急性胰腺炎的病因、药物治疗方案的设计以及药学监护计划的实施.方法:对1例急性胰腺炎的临床资料、治疗方案等进行分析.结果:发现本例重症胰腺炎患者经过16日的治疗好转出院.结论:临床药师参与本例重症急性胰腺炎的治疗药学监护具有很大的临床意义.

Objective To investigate the extent of pancreatic and liver function damage of acute necrotizing pancreatitis (ANP) rats under altitude hypoxia environment,and to provide a reference for better diagnosis and treatment of severe acute pancreatitis (SAP) in the plateau region.Methods Ninety-six specific pathogen free (SPF) Wistar male rats were involved in 1 500 meters,3 300 meters and 4 300 meters altitude.The model of ANP was established by using pancreatic capsule injection of sodium taurocholate (NaTc).In the sham operation group,the rats' belly was opened and closed after only flipping its pancreas several times.Rats in sham group were sacrificed at 6 h,and ANP group were sacrificed at 6,12,24 h after modeling.Serum amylase activity was measured,and pancreas and liver tissue were harvested for pathological examination and score.Results Serum amylase activity in sham operation group rats was not remarkably changed,and pathological changes of pancreas and liver were not obvious.At same altitude,serum amylase activity,pancreas and liver pathology score of ANP rats at each time point were significantly higher than those in the sham operation group;and serum amylase activity,pancreas and liver pathology scores of ANP 12,24 h group rats were significantly higher than those of ANP 6h group;and the difference was statistically significant (P ＜ 0.05).At 3 300 meters,4 300 meters altitude,the pancreas and liver pathology scores of ANP rats at each time point were significantly higher than those at 1 500 meters altitude,and the differences were statistically significant (P ＜ 0.05),but the difference in serum amylase activity was not statistically significant.Conclusions With the increase of altitude,pancreatic and liver pathological damage of ANP rats shows continuing aggravation.

目的:了解男性节育技术现状及进展,为今后开展男性避孕节育技术提供科学依据.方法:通过对近年来国内计划生育期刊中部分男性避孕节育技术文献资料归类整理,全面了解男性节育技术的现状和进展情况.结果:目前临床可选择的男性避孕节育技术仅有避孕套和输精管结扎术两种安全有效的成熟方法,而输精管堵塞术、输精管内安装节育器、免疫避孕法、药物避孕法等新兴的男性避孕节育方法其安全性及有效性还有待进一步论证、商榷和研究.结论:在我国计划生育政策中,男性共同承担与生殖行为相关事务的责任,对改善妇女健康是必不可少的,男性的态度和行为决定着计划生育和生殖健康的进一步发展.因此,维持我国当前的低生育水平,进一步控制人口增长,加快开发和推广男性节育的新技术、新方法,也是计划生育工作的重要内容.

OBJECTIVE:To investigate the drug use in the outpatient and emergency department so as to reduce the incidence of adverse drug reactions and promote rational use of drugs. METHODS: 400 outpatient & emergency prescriptions collected monthly ( 4 800 prescriptions in total ) were reviewed in accordance with to the “Management Practices on Hospital Prescription Review( Trial)”. RESULTS:248 outpatient prescriptions were unqualified, and the irrational use of drugs manifested as incompatibility between drug use and the clinical diagnosis, inappropriate in usage& dosage or drug combination, incompatibility and improper use of solvents etc. CONCLUSIONS: Regular review on prescriptions and analysis of the problems in clinical drug use and timely intervention can help improve clinicians?level in rational use of drugs.