子宫内膜息肉(EP)是常见的妇科疾病之一,其发病机制目前尚不明确.近年来随着诊疗水平的提高、辅助检查技术的完善和广泛应用,EP患者越来越多见,且存在恶变的可能.目前EP的治疗多以手术治疗为主,但易复发,为降低EP的复发率,临床上常建议患者在经手术去除息肉后服用屈螺酮炔雌醇片或放置曼月乐环.但不论何种治疗方法都有其局限性,因此,对于EP发病机制的探究显得尤为重要,亟待找出更有效的方式治疗EP.本文就EP发病机制的研究进展进行综述.

目的:分析二甲双胍治疗多囊卵巢综合症的临床效果.方法:选取2015年1月至2017年3月本院门诊收治的60例多囊卵巢综合症患者作为研究对象,随机将患者分成两组,一组采用二甲双胍进行治疗,为观察组,另一组采用达因35及二甲双胍进行治疗,为对照组,对比分析两组患者的体征指标改善情况.结果:观察组患者治疗后LH水平为(5.6±1.2)U/L,FSH水平为(6.2±3.1)U/L,睾酮水平为(1.2±0.3)nmol/L,胰岛素水平为(8.2±2.2)mIU/L,各项指标与对照组相比具有统计学意义(P<0.05).结论:二甲双胍治疗多囊卵巢综合症效果明显,可有效恢复患者的各项临床指标,加快患者康复,本药可在多囊卵巢综合症的临床治疗中进一步推广使用.

Objective To investigate the relationship between fibrosis and M2 macrophages in endometriosis. Methods BALB/c mice model of endometriosis was established by intraperitoneal injection. The growth of ectopic lesions in mice was observed on the 7th,14th and 21th day after modeling. Masson staining was used to observe the degree of fibrosis and immunohistochemical method to detect the expression of CD206 and CD68 of mice. Image-Pro-Plus 6.0 was used for semi quantitative analysis of staining and the correlation between the degree of fibrosis and the expression of M2 macrophages was explored. Results The success rate of the establishment of endometriosis model by intraperitoneal injection was 100%. There was a positive correlation between fibrosis and the expression of M2 macrophages in endometriosis mice model. Conclusions The mice model of endometriosis can be established successfully by intraperitoneal injection and M2macrophages may promote fibrosis in endometriosis.

目的 将依托咪酯复合地佐辛和丙泊酚、丙泊酚复合芬太尼分别在无痛人流术中应用,分析及评价其应用价值.方法 2015年7月～2017年9月本院纳入的140例无痛人流患者收入此文分析资料,参考麻醉用药不同予以分组,丙泊酚复合芬太尼予以参照组患者(70例),依托咪酯复合地佐辛、丙泊酚予以实验组患者(70例),计算2组患者的麻醉起效用时、意识恢复用时、注射痛例数、恶心呕吐例数、肌阵挛例数,术中出血量.结果 实验组患者的意识恢复用时、注射痛例数、恶心呕吐例数、肌阵挛例数与参照组患者数值比较更优,差异有统计学意义(P<0.05),术中出血量差异无统计学意义.结论 无痛人流患者采取依托咪酯复合地佐辛和丙泊酚的麻醉效果对比丙泊酚复合芬太尼更优.

Objective To acquire the information on the osteoporosis knowledge related to gynecologist in soochow countryside community health service center.Methods Subject gynecologist Soochow countryside community health service center were inquired about the knowledge related to osteoporosis by questionnaire.Results There is limited understanding and misunderstanding about the knowledge related to osteoporosis.Conclusion Specialized osteoporosis health education should be recommended in gynecologist of countryside community health service center.

目的探讨丙泊酚联合芬太尼在无痛人工流产术中应用的临床疗效。方法对41例早孕妇女,在常规消毒的同时,静脉注射芬太尼1μg/kg,丙泊酚2.5mg/kg作为观察组,同期将40例早孕妇女术前用2%利多卡因宫颈旁神经阻滞作为对照组。观察比较两组的镇痛效果、宫口扩张、出血量及人流综合征的发生率。结果镇痛效果:观察组优良者占92.7%,显著高于对照组67.5%(P<0.05);宫颈扩张:观察组总有效率90.2%,高于对照组57.5%(P<0.05);人流综合征:观察组无一例发生,而对照组有10%的发生率(P<0.05);术中出血量:两组比较无显著差异(P<0.05)。结论丙泊酚联合芬太尼静脉注射,是一种安全、有效、方便的麻醉镇痛方法之一。在麻醉师的配合下,可应用于早孕妇女中无痛人流术。

目的探讨农村妇女子宫肌瘤的手术方式及求医状况。方法对2004年苏南农村和苏北农村子宫肌瘤病人的手术方法,求医状况和就医环境进行统计比较。结果两地妇女子宫肌瘤的发病率无明显差异。结论妇女病普查十分重要,及时针对肌瘤部位、个数,生育要求选择适当手术方法。