Objectives? To explore the effectiveness and safety of the health cloud headphones (HCH) in patients with mild and moderate generalized anxiety disorder (GAD). Methods? A total of 100 mild and moderate GAD outpatients who met the DSM-5 diagnostic criteria for GAD were recruited and randomly assigned into the experimental group and control group, with 50 cases in each group. The experimental group was treated using HCH while the control group was treated using duloxetine. All patients received an 8-week treatment. The effectiveness was evaluated by Hamilton Anxiety Rating Scale (HAMA) and the safety of treatment was assessed by Treatment Emergent Symptom Scale (TESS) before the treatment, 4 weeks into the treatment and at the end of the 8-week treatment. Results? Two-factor repeated measure analysis of variance showed that there was no significant difference in the effects of group and time interaction on the HAMA scales of psychotic anxiety factors, somatic anxiety factors and total scores (F=2.360,0.539,2.402,P>0.05). There was no significant difference in the main effect of group factors on the change of scale scores (F=0.033,1.111,0.482,P>0.05), while the main effect of time factors was statistically significant (F=133.260,52.091,121.092,P<0.001). Further comparison between the two groups showed that there were significant differences in the changes of psychotic anxiety factors, somatic anxiety factors and total scores between before the treatment and 4 weeks into the treatment (P<0.01). There were significant differences in the scores between the 4 weeks into the treatment and at the end of the treatment (P<0.05). There was no significant difference between the experimental group and the control group in terms of effectiveness rate (88.9% vs 92.9%) and marked effectiveness rate (53.3% vs 66.7%) (χ2=0.410, 1.606, P>0.05). The incidence of adverse reactions in the experimental group was lower than that in the control group (χ2=4.960, P<0.05). Conclusions? The effectiveness of HCH in treatment of patients with mild and moderate GAD was similar to duloxetine, while the HCH therapy can improve symptoms with higher safety.
目的 本文旨在研究辩证行为疗法(Dialectical Behavior Therapy,缩写为DBT)在治疗有自杀/自伤倾向的抑郁症患者的应用,并评估其疗效.方法 以2017年12月~2018年6月间在解放军第102医院心理咨询中心接受治疗的58例有自杀/自伤倾向的抑郁症患者作为研究对象;将这些患者随机均分为两组,即研究组与对照组,对他们进行药物治疗.其中,研究组在接受药物治疗后继续接受DBT.最后,采用Beck自杀意念量表对两组患者的自杀意念及抑郁症状进行评估和比较分析.结果 在接受6个和9个星期的治疗后,研究组的Beck自杀意念量表评分均低于治疗组(P<0.05).结论 辩证行为疗法可有效减轻有自杀倾向抑郁症患者的抑郁程度,降低他们的自杀意念.
In the treatment of post-traumatic stress disorder ( PTSD) , the theory modes and technical opera-tion of exposure therapy are relatively simple, easy to operate and generalize, and its therapeutic effect is supported by a large amount of empirical research;however, exposure therapy of PTSD is a kind of therapy with high-risk and high expulsion rate and triggers some ethical controversies. The supporters and opponents of PTSD exposure therapy argued from the perspective of professional ethics of psychological counselor, safety risks, technical opera-tion hidden dangers, humanistic care and human nature instinct and so on.