To investigate the docetaxel for locally advanced non small cell lung cancer survival,curative effect and side reaction. Methods 40 patients with locally advanced non small cell lung cancer were randomized into test group,and combined group,two cases were with IMRT plan,irradiation dose of 60GY,2GY /,5 times /week,combined with docetaxel group,40mg,D1,8,15,22 days.Results in the combined group and B group total effective rate were 80% and 50%,there were significant differences (P <0.05):a median overall survival of 15 months,only put the median overall survival of 12 months,the joint group of 18 months,two groups of side effects,patients can tolerance.Conclusion docetaxel combined with three dimensional conformal radiotherapy with radiotherapy for locally advanced non small cell lung cancer is high,longer survival time,does not increase the adverse reaction.

目的：研究胸腺五肽联合吉西他滨联合卡铂方案化疗治疗晚期肺鳞癌的临床效果。方法56肺鳞癌随机分为两组,治疗组：吉西他滨+卡铂方案+胸腺五肽。双氟胞苷(健择)1250 mg/m静脉滴注,第1、8天,卡铂250~300 mg/m,静脉滴注,第1天。化疗后第3天每日静脉滴注胸腺五肽1mg,连续7 d。对照组：单化疗,用吉西他滨+卡铂方案,剂量、用法同上。结果治疗后，治疗组在CD4与NK细胞活性、治疗有效率、1年生存率等方面都比本组化疗前以及对照组化疗后水平效果好，差异无显著性(P<0.05)。结论胸腺五肽联合化疗能提高肺癌化疗患者机体的免疫功能,改善患者生存质量。