OBJECTIVE To compare the clinical efficacy of distal radius T-plate combined with suture anchor and distal clavicle anatomical locking plate combined with suture anchor in the treatment of Neer Ⅱb distal clavicle fracture. METHODS From June 2014 to June 2018, 42 patients with Neer Ⅱb distal clavicle fractures were retrospectively analyzed. According to different surgical methods, they were divided into the observation group (T-shaped plate combined with suture anchor) and the control group (anatomical locking plate combined with suture anchor). There were 22 patients in the observation group and 20 patients in the control group. In the observation group, there were 13 males and 9 females, aged from 22 to 70 (45.78± 14.44) years old, 12 cases on the left side and 10 cases on the right side, 8 cases of traffic accident injury and 14 cases of fall. In the control group, there were 12 males and 8 females, aged from 24 to 66 (44.17±15.58) years, 13 cases on the left side and 7 cases on the right side, 6 cases of traffic accident injuryand 14 cases of fall. The operation time, intraoperative blood loss and fracture healing time were compared between the two groups, and Constant Murley score was used to evaluate shoulder joint function. RESULTS The patients in both groups were followed up for 18 to 24 (20.96±2.02) months. The incisions of both groups were healed at stageⅠ. The fracture ends of both groups were bony healed at the last follow up. There was no significant difference in operation time, intraoperative blood loss and fracture healing time between two groups (P>0.05);there was no significant difference in shoulder joint function between two groups at 3 months after operation (P>0.05). CONCLUSION The two methods can obtain satisfactory results in the treatment of Neer Ⅱb distal clavicle fractures, especially suitable for patients with comminuted distal clavicle fractures or osteoporosis; the clinical effect of the treatment of NeerⅡb distal clavicle fractures with T type distal radius plate combined with suture anchor is satisfactory, which provides another feasible treatment scheme for clinic.

Osteosarcoma is a malignant tumor that occurs in children and adolescents. Although treatments for osteosarcoma have improved, the likelihood of survival remains low for most patients with metastasis and recurrence. Elucidating the mechanism underlying the development of osteosarcoma and chemotherapy resistance will be important to improve diagnosis and treatment. Long non-coding RNAs (lncRNAs), which are longer than 200 nucleotides in length and do not encode for proteins, have been shown to play a regulatory role in the occurrence and development of osteosarcoma, and are expected to serve as biomarkers and molecular targets. This review discusses the progress in the study of the role of lncRNAs in osteosarcoma, and highlights the recent developments in this field.

目的:观察腓骨远端解剖钢板治疗旋后-内收型Ⅱ度内踝骨折的临床疗效.方法:自2010年3月至2017年8月,对28例旋后-内收型Ⅱ度踝关节骨折患者,采用腓骨远端解剖钢板固定内踝骨折,术后评估其临床疗效.结果:本组28例患者均获得6～24个月随访,平均随访时间14个月.所有患者伤口均I期愈合,术后1,3,6及12个月复查踝关节X线片,28例患者骨折均获得愈合,平均愈合时间16.8周.根据AOFAS踝-后足评分系统评价:术后评分75～94分,优16例,良9例,可3例.结论:采用腓骨远端解剖钢板治疗旋后-内收型Ⅱ度内踝骨折,固定坚固,对软组织损伤较小,并发症少,临床效果满意.

目的:分析超声辅助下闭合复位克氏针固定治疗儿童肱骨髁上骨折的临床研究.方法:将40例儿童肱骨髁上骨折患者选为研究对象,为其选取超声辅助下闭合复位克氏针固定进行治疗,评估并探讨其治疗效果.结果:40例患者伤口均在Ⅰ期愈合,无感染、神经损伤、并发症发生,患者骨折均对位对线良好、固定坚强、获得愈合,愈合时间10～24周,平均为(12.8±6.5)周.结论:超声辅助下闭合复位克氏针固定治疗儿童肱骨髁上骨折的临床效果显著,具有较高的安全性,值得推荐.