选取笔者所在医院2012年11月~2015年10月确诊治疗的溃疡性结肠炎患者124例作为结肠炎组，依据治疗疗效分为有效组和难治组，同期选取体检科健康人员30例作为健康组，采用 PCR 技术检测巨细胞病毒的表达，统计分析所有研究对象的巨细胞病毒感染情况。结果结肠炎组和健康组巨细胞病毒阳性率分别为，前者明显高于后者，差异有统计学意义(P<0.05)；有效组和难治组巨细胞病毒阳性率分别为，前者明显低于后者，差异有统计学意义(P<0.05)。巨细胞病毒感染与溃疡性结肠炎的发生发展有关，且难治性患者的阳性率较高，提示医师应重点关注受感染的患者，以确保临床疗效。

目的：探究胱抑素 C 与缺血性脑卒中相关性。方法我院2012-03-2014-03急诊留观或神经内科收治的50例缺血性脑卒中患者(研究组)以及在我院同期进行体检的50例正常人(对照组)为研究对象。分析2组患者的危险因素及血清胱抑素 C 水平；胱抑素 C 与其他相关危险因子的相关性,分析胱抑素 C 与上述危险因素是否存在正相关性,了解胱抑素C 与缺血性脑卒中的关系。结果2组患者的性别和三酰甘油差异无统计学意义(P >0.05)；年龄、升高、体质量、BMI、血压、血糖、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇和胱抑素 C 比较差异均有统计学意义(P <0.05)；研究组患者的性别、吸烟史、身高、体质量、BMI,总胆固醇、三酰甘油、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇等与胱抑素 C 无相关性(P >0.05)；患者收缩压、血糖水平以及年龄与胱抑素 C 存在相关性(P <0.05),且患者收缩压、血糖水平升高、年龄与胱抑素 C 呈正相关；对胱抑素 C 与缺血性脑卒中的相关性进行分析结果显示,胱抑素 C 与缺血性脑卒中有相关性且胱抑素 C 是影响患者患有缺血性脑卒中的独立因素(P <0.05)。结论胱抑素 C 与缺血性脑卒中有相关性,且与缺血性脑卒中的收缩压、血糖水平及年龄因素有正相关性,能够用于临床患者缺血性脑卒中的早期诊断,对预防、治疗具有重大意义,且具有一定的社会效益、经济效益,具有推广前景。

Objective:To observe the effect of Lidan Decoction treatment for postoperative gallbladder stones recurrence. Method:93 cases of patients with gallbladder stones were selected and randomly divided into observational group (n=47) and control group (n=46),patients on control group were given routine treatment,and the observational group were given Chinese medicine Lidan Decoction oral.Extraction time of T tube postoperatively,gallbladder contraction function,and rate of stone recurrence and recrudesce were compared between the two groups.Results:Extraction time of T tube postoperatively of observational group was significantly shorter than that of control group (P<0.05),and gallbladder contraction function was significantly better than that of control group (P<0.05);The rate of stone recurrence and recrudesce of observational group was significantly lower than that of control group (P<0.05).Conclusion:The application of Lidan Decoction can effectively prevent postoperative gallbladder stones recurrence and improve the contraction function of gallbladder.

Objective Clinical efficacy in patients with coronary heart disease tachyarrhythmia amiodarone therapy. Methods In our hospital from January 2012 to January 2014 were treated 60 cases of coronary heart disease complicated by tachyarrhythmias in patients of all emergency patients were given amiodarone therapy, and efficacy determination. Results The group of 60 patients after amiodarone total effective rate of 90.0%, adverse reactions were mild and no serious adverse events. Conclusions Amiodarone in the treatment of coronary artery disease in patients with tachyarrhythmia safe and effective.

Objective To investigate the relationship between Cys C and ischemic stroke. Methods 126 ischemic stroke patients who had treatment from November 2012 to November 2013 in our hospital were selected as experimental group.Among them, 105 cases had hypertension and 25 cases haddiabetes mellitus. 30 healthy persons with similar age and sex as experimental group were selectedas control group. And 20 cases Diabetes mellitus group, 40 cases hypertension patients and 20 cases coronary heart disease patients were also selected for this study.Cys C and ischemic stroke related measures such as blood pressure and blood sugar levels were determined in the two groups. The relationship between Cys C and ischemic stroke related measures was analyzed. Results Compared with control group,the Cys C level of experimental group at the onset of disease, after the onset of the disease and after treatment was increased significantly(P 0.05). Ischemic stroke patients with hypertension or diabetes had significant higher Cys C level than that of the patients with only high blood pressure, coronary heart disease or simple diabetes(P 0.05). Logistic regression analysis showed that hypertension and Cys C are independent risk factor of ischemic stroke. Cys C level in ischemic stroke patients was positively correlate with systolic blood pressure(r=0.593,P0.05), blood glucose level(r=0.534,P0.05)and the age(r=0.568,P0.05). Conclusions Cys C level can assist in the diagnosis of ischemic cerebral apoplexy. In patients with cerebral apoplexy. Therefore increase inblood pressure and blood glucose levels and together with the increase of Cys C level may alert for the occurrence of ischemic cerebral apoplexy.

Objective To investigate the predictive value of serum B-type natriuretic peptide(BNP) for the left ventricle function at early stage of chronic obstructive pulmonary disease(COPD).Methods Sixty patients with early COPD treated in our hospital between Jan 2013 and Feb 2014 were selected as observation group.Thirty normal healthy subjects of the same age were used as control group.Serum BNP levels of patients in the observation group were measured before and after treatment.The serum BNP level in the control group was also tested.The serum BNP levels,LVEF,FEV1,FVC and the relationship between the serum BNP levels and LVEF were compared.Results Compared with before treatment,the serum BNP levels in the observation group were significantly decreased.Compared with the control group,the serum BNP levels in the observation group were significantly increased(P 0.05).The differences in FEV1,FVC and LVEF between the two groups were also statistically significant(P 0.05).The area under the ROC curve of serum BNP was 0.806.With the increase of BNP levels of the patients in the observation group,LVEF was decreased.There was a significant correlation between the two parameters(r =-0.826,P 0.05).Conclusion At early stage of COPD,serum BNP level is increased while LVEF is decreased suggesting that heart function has been influenced.

目的 探讨呼吸机相关性肺炎(VAP)的危险因素及其病原菌的构成.方法 回顾性分析2010年1月到2013年10月进行机械通气的210例患者中115例VAP发生情况,相关因素以及病原菌培养结果.采用单因素分析和多因素logistic回归分析VAP的危险因素.结果 单因素分析结果显示,VAP的危险因素有机械通气时间、插管次数、住院时间、年龄和原发病等.多因素logistic回归分析结果显示,VAP的独立危险因素有插管次数(OR =2.219,P=0.040)、机械通气时间(OR =5.674,P=0.000)和住院时间(OR=2.014,P=0.030)等,其中机械通气时间与VAP的相关度最大.105例患者中共分离出225株病原菌,其中革兰阴性菌176株(78.22％),革兰阳性菌44株(19.56％),真菌5株(2.22％),前三类主要的病原菌为鲍氏不动杆菌、铜绿假单胞菌和肺炎克伯雷菌.结论 VAP的危险因素主要有机械通气时间、插管次数、住院时间、年龄和原发病等.引发VAP的病原菌主要有革兰阴性菌.

　　目的观察奥曲肽联合奥美拉唑在肝硬化上消化道出血中的作用以及临床疗效。方法对我院2010年1月至2012年1月间收住入院的93例肝硬化上消化道出血的病人进行回顾性调查研究，其中单用奥曲肽组45例、奥曲肽联合奥美拉唑组48例，观察两组药物的临床止血作用，并详细记录止血的时间以及副反应等观察指标。结果奥曲肽联合奥美拉唑组对肝硬化上消化道止血的有效率明显高于奥曲肽组（P＜0.05）。副作用方面，奥曲肽联合奥美拉唑组则明显低于奥曲肽组（P＜0.05）。结论奥曲肽联合奥美拉唑治疗肝硬化上消化道出血疗效确切，止血效果好，副反应少，值得临床推广。