Objective:To understand the risk factors of the prognosis of children with hand, foot and mouth disease(HFMD), and the threshold of related indexes.Methods:By retrospective analysis, 80 HFMD children admitted to Zhongshan County People's Hospital from September 2018 to November 2019 were selected. According to the prognosis, the children were divided into good prognosis group ( n=55) and poor prognosis group ( n=25). The general data, occurrence of related symptoms, laboratory indicators were compared between the two groups. ROC curve was used to determine the value of biochemical indicators in predicting the prognosis of HFMD children. Differential information was included in the Logistic regression model to identify the risk factors of poor prognosis of HFMD children. Results:The areas under the curve of lactate clearance, cardiac output and PaO 2/FiO 2 were 0.879, 0.767 and 0.675, respectively. Logistic regression analysis showed that lactate clearance rate < 25.655% ( OR=2.689, 95% CI: 1.467-4.929), cardiac output<2.465 L/min( OR=1.487, 95% CI: 1.078-2.051), PaO 2/FiO 2<271.645 mmHg (1 mmHg=0.133kPa) ( OR=3.689, 95% CI: 1.251-10.878), hyperglycemia >8.3 mmol/L ( OR=5.423, 95% CI: 1.389-21.173) and convulsion( OR=11.258, 95% CI: 1.201-105.531) were the risk factors for poor prognosis of HFMD. Conclusions:Early symptoms such as hyperglycemia and convulsion, lactate clearance rate < 25.655%, cardiac output < 2.465 L/min, PaO 2/FiO 2 <271.645 mmHg may cause poor prognosis in children with HFMD, and it requires timely attention of clinicians and intervention.

目的 总结超声对脑梗死患者颈动脉斑块声像特征观察情况.方法 回顾性分析80例脑梗死患者颈动脉超声检查结果,并分析总结斑块声像特征.结果 80例例患者均检出颈动脉粥样硬化斑块,斑块最常见的发病部位为颈动脉交叉处,稳定斑块15例,不稳定斑块65例.超声发现的颈动脉粥样硬化斑块类型与CT所检出的脑梗死病灶基本保持一致.结论 临床可通过判断颈动脉粥样硬化斑块性质,为临床预防及治疗脑梗死提供可参考依据.