目的:探讨儿童维生素A水平与儿童反复呼吸道感染关系的相关性.方法:选取我院2017年10～2021年10月间儿科收治的425例反复呼吸道感染患者作为观察组,同期来我院参加健康体检的健康儿童426例作为对照组,总共851例.测定两组儿童血清中维生素A的水平,分析反复呼吸道感染和体内维生素A水平高低的相关性.结果:观察组反复呼吸道感染患者的维生素A水平显著低于对照组(P＜0.05);观察组患儿维生素A缺乏概率显著高于对照组正常儿童(P＜0.05).结论:反复呼吸道感染发病与儿童体内维生素A水平的高低有重要的相

目的 考察甘孜藏族自治州0～6岁儿童血清维生素A(VitA)水平,为预防VitA相关疾病的发生提供参考依据.方法 2017年4月-2019年4月在甘孜州乡城县和稻城县对2122名藏族儿童进行体格检查,并采用高效液相色谱法检测血清VitA的含量.结果 2122名0～6岁儿童血清VitA平均水平为(1.05±0.27)μmol/L,亚临床缺乏率为8.15％,可疑亚临床缺乏率为45.99％.婴儿组VitA平均水平为(0.94±0.26)μmo1/L,低于幼儿组[(1.09±0.28)μmol/L]和学龄前儿童组[(1.05±0.27)μmol/L](F=15.308),海拔4km以上VitA平均水平为(0.96±0.19)μmol/L,低于海拔2～3 km[(0.99±0.26)μmol/L]和3～4km[(1.12 ±0.27)pmol/L](F= 61.735),夏季VitA 平均水平高于其他季节(F=52.194),差异均有统计学意义(P＜0.001).此外0～1岁组亚临床缺乏率为23.97％,高于其他年龄段(x2=43.503,P＜0.001).Logistic回归分析结果显示海拔高度、季节和年龄对亚临床缺乏和可疑亚临床缺乏均有影响,其中随着海拔升高亚临床缺乏和可疑亚临床缺乏发生几率增大.结论 甘孜藏族自治州0～6岁儿童VitA平均水平较低,以可疑亚临床缺乏为主,VitA的缺乏与年龄、海拔、季节相关,不同年龄阶段儿童应根据当地海拔高度、不同季节补充VitA及富含VitA的食物,以预防VitA缺乏及相关疾病的发生.

Objective:To detect serum levels of vitamin A (Vit A), vitamin D(Vit D)25-hydroxy vitamin D[25-(OH)D] and vitamin E(Vit E) in children aged 0-6 years in Tibetan Plateau of Garzi Prefecture, thus providing references for physical examinations and prevention of 4 key diseases (rickets, malnutrition anemia, pneumonia and diarrhea) in children in plateau areas by relevant government departments.Methods:A total of 2 122 children who participated in physical examination in 12 townships of Xiangcheng County and 14 townships of Daocheng County, Garzi Tibetan Autonomous Prefecture, Sichuan Province from April 2017 to April 2019 with 0-6 years old were recruited for surveying physical measurements and collection of venous blood.Serum Vit A and Vit E levels were detected by high performance liquid chromatography.Serum levels of 25-(OH)D were detected by high performance liquid chromatography tandem mass spectrometry.The relationship between Vit A, Vit E and 25-(OH)D levels with the gender, age, seasonal change and altitude was analyzed.Results:The serum Vit A level, subclinical Vit A deficiency rate and marginal vitamin A deficiency rate were(1.05±0.27) μmol/L, 8.15%(173/2 122 cases) and 45.99%(976/2 122 cases), respectively in 2 122 children with 0-6 years old.There were significant differences in the serum Vit A level, the subclinical Vit A deficiency rate and the marginal vitamin A deficiency rate in children with different ages, seasons and altitudes (all P<0.05). The serum level of 25-(OH)D and 25-(OH)D deficiency rate insufficient rate were (24.65±6.45) ng/L, 6.03%(128/2 122 cases) and 16.59%(352/2 122 cases), respectively.There were significant differences in the serum level of 25-(OH)D, 25-(OH)D deficiency rate and 25-(OH)D insufficient rate in children with different ages and seasons (all P<0.05). The mean serum Vit E level, Vit E deficiency rate and Vit E insufficient rate were (7.81±1.74) mg/L, 2.78%(59/2 122 cases) and 29.59%(628/2 122 cases), respectively.There were significant differences in serum Vit E level, Vit E deficiency rate and Vit E insufficient rate in children with different ages and seasons (all P<0.05). The mean serum levels of Vit A and Vit D remained the lowest before the age of 1 year, and their deficiencies at this age were the most significant.The mean serum level of Vit E remained the lowest in >1-2 years old, and its deficiency and insufficient at this age were the most significant.Vit A, D and E levels were significantly affected by seasonal changes, which were significantly higher in the summer than in the spring, autumn and winter.In addition, Vit A and 25-(OH)D were significantly affected by the altitude, which were the lowest above 4 km altitude. Conclusions:The overall serum levels of Vit A, 25-(OH) D and E in children with 0-6 years old in Tibetan Plateau areas of Ganzi Prefecture are lower than those in plain areas.Vit A, 25-(OH) D and Vit E levels significantly differed in the age, season and altitude, which are related to the lack of local resources, insufficient maternal nutrition during pregnancy and insufficient intake after birth, as well as temperature and light caused by changes in local seasons and altitude.Therefore, it is necessary to make reasonable supplements during pregnancy to prevent vitamin deficiency.

目的:探讨四川省甘孜藏族自治州（以下简称甘孜州）高原地区3～7岁儿童维生素D[25-（OH）D]营养状况与龋齿发病率的关系。方法:2017年11月至2018年4月,选取四川省甘孜藏族自治州乡城县、稻城县3～7岁藏区儿童810名,检测血清25-（OH）D水平,调查儿童龋齿发生情况。结果:＞6～7岁组龋齿发病率为57.44%,明显高于3～4岁组、＞4～5岁组（P＜0.05）;＞5～6岁组、＞4～5岁组龋齿发病率为52.03%和43.68%,明显高于3～4岁组（P＜0.05）;＞6～7岁组儿童血清25-（OH）D为（22.92±5.15） ng/mL,明显低于3～4岁组、＞4～5岁组（P＜0.05）;＞6～7岁组25-（OH）D缺乏或不足儿童龋齿发病率为62.34%,明显高于3～4岁组（P＜0.05）;＞5～6岁组25-（OH）D缺乏或不足龋齿发病率为58.93%,明显高于3～4岁组（P＜0.05）。结论:甘孜州高原地区3～7岁儿童龋齿、25-（OH）D缺乏或不足的比例较高,其中龋齿发生与25-（OH）D缺乏或不足有一定关系。

子宫肌瘤是妇科常见的一种盆腔良性肿瘤,属于女性特有疾病,20岁以下的女性较少见,30-50岁的女性较多见.有调查发现,目前我国患有子宫肌瘤的女性约占所有女性的20％-50％,不仅影响到了女性朋友的身体健康,还给女性朋友们带来了较大的心理负担,降低了生活质量.而且由于缺乏对子宫肌瘤疾病的知识普及,也导致许多朋友对子宫肌瘤这一疾病还存在许多不了解的地方,所以今天咱们就来给大家科普一下有关子宫肌瘤的相关知识.

高血压是一种老年常见病,其给老年人的生活带来较大不便.作为高血压病症的重要形式,单纯收缩期高血压的发病概率较高,而且发病原因较为复杂,对老年人的危害性更大.生活中,一旦老年人患单纯收缩期高血压,就应严格按照医生的嘱咐,进行降压预防控制和治疗.

小儿腹泻是一种世界性的疾病,而全球大约每年至少十亿人次发生腹泻.根据世界卫生组织的调查,每天约有一万人死于腹泻.在我国腹泻病一样是儿童的常见病,据相关资料显示,我国五岁以下儿童的腹泻年发病率在201% ,而平均每年每个儿童的年发病次数在三点五次,死亡率在百分之零点五一.所以对于小儿的腹泻防治,是非常重要的,腹泻病的种类有急性腹泻病、迁延性腹泻病、慢性腹泻病.那么孩子腹泻的病因与症状有哪些? 是否可以给孩子补锌呢? 就让我们一起来了解一些吧.