Objective To discuss the feasibility and effect of immediate breast reconstruction with pedicled greater omentum and gel prosthesis following nipple and areola complex sparing mastectomy. Methods From August 2013 to September 2015, after mastectomy with conservation of nipple and areola, twenty-three patients with stage 0,Ⅰ,Ⅱbreast cancer accepted immediate breast reconstruction with pedicled greater omentum and gel prosthesis. Results All the pedicled greater omentum was successfully inserted, and no prosthesis migration and rupture occurred 3 to 25 months after operations. The reconstructed breast was good in shape and with soft feeling. Nipple ischemia occurred in two patients with ductal carcinoma in situ, while skin necrosis was not found within 3 months. There was no recurrence of breast cancer during follow-up period. Conclusion Immediate breast reconstruction with pedicled greater omentum and gel prosthesis after mastectomy with conservation of nipple and areola is an effective and safe procedure.

Objective: To compare the impacts between breast-conserving surgery and modified radical treatment on clinical efficacy and quality of life in patients with early breast cancer. Methods: The clinical data of 95 patients with early breast cancer undergoing breast-conserving therapy(breast-conserving group) between July 2004 and July 2007 were analyzed,and were compared with those of 95 matched patients over the same period undergoing modified radical mastectomy(modified radical group). Results: There were no significant differences between the two group in recurrence,metastasis and survival rate(all P0.05).The rate of aesthetically excellent breast shape in breast-conserving group and modified radical group was 93.7% and 0,respectively(P0.05).The quality-of-life score of the 5-year survival patients in breast-conserving group was significantly higher than that in modified radical group(83.66±3.70 vs.73.07±4.85)(P0.05). Conclusion: In early breast cancer patients,breast-conserving surgery can achieve the same therapeutic efficacy as modified radical mastectomy,and meanwhile significantly improve their quality of life.Strict observation of the indications,standardized surgical resection and individualized,comprehensive postoperative management are critical to success of breast-conserving treatment.