In order to provide a reference for clinical applications, effects of Low Intensity Laser Irradiation(LILI) with combination of 635/808nm on cutaneous wound healings are evaluated. Non-surgical treatment of 60 patients with malignant tumors, the test group and control group of 30 cases is randomly selected. The incision site of patients has been irradiated with laser, which generated two lasers. One was red laser with wavelength at 635 ± 5nm and power density at 1~6.5 mW/cm^2; the other was infrared laser with wavelength at 808 ± 5nm and power density at 11~32 mW/cm^2. Laser treatment was started 24 hours after the end of surgery, each Days once every 15 minutes exposure to treatment endpoint. He-Ne laser treatment began 24 hours after the end of surgery, day 1, each exposure 15 minutes, until the end of treatment (hospital or wound healing stitches). The result shows that LILI with the combination of 635/808 nm could improve cutaneous wound healings of patients significantly rather than using He-Ne laser.

<正>目的:探讨光动力疗法对肝癌细胞SMMC-7721凋亡的影响。方法:以血卟啉单甲醚(HMME)为光敏剂,波长635nm激光为激发光源的光动力疗法作用于肝癌SMMC-7721细胞。细胞分别与浓度5、10、20、30μg/ml的光敏剂孵育4h后,用不同能量密度的激光照射。MTT法检测HMME的暗毒性以及光动力疗法作用24h后的细胞活性。Hoechst细胞

探讨弱激光对糖尿病大鼠皮肤创伤愈合过程的影响.32只糖尿病大鼠背部皮肤全层创口随机分为4组,分别为:功率密度5、10和15 mW/cm2的630nm半导体激光照射组及空白对照组.弱激光照射能明显加速创面收缩,减轻炎症反应,加快成纤维细胞的增殖和胶原蛋白的合成,促进上皮细胞和毛细血管再生,促进创伤愈合.其中功率密度15 mW/cm2的弱激光治疗组疗效最为明显.实验前后各组大鼠血糖水平均无显著差异.弱激光对糖尿病大鼠皮肤创伤愈合确实存在促进作用,且疗效存在光学参数依赖性.