Objective To observe the effects of neuromuscular exercise(NEMEX)training combined with semiconductor la-ser therapy on patients with knee osteoarthritis(KOA).Methods A total of 60 patients with knee osteoarthritis who were treated in the Rehabilitation Medicine Department of the First Affiliated Hospital of Bengbu Medical University from August 2023 to March 2024 were selected and randomly divided into control group and observation group using a random number table method,with 30 cases in each group.The control group received conventional rehabilitation treatments,including joint mobilization and medium-fre-quency electrical stimulation,along with semiconductor laser therapy at a wavelength of 808 nm and an irradiation power of 400-800 mW,continuous irradiation,20 minutes per session,once daily,five times weekly for a total of four weeks.The observation group received NEMEX training in addition,including 10 minutes of warm-up exercise;40 minutes of NEMEX training(stability,posture orientation,lower limb muscle strength training,and functional exercises);and a 10-minute cool-down exercise(involving gait adjustment and stretching),once daily,five times weekly for four weeks.Before and after treatment,Visual Analog Scale(VAS)was used to assess the degree of pain;Western Ontario and McMaster University Osteoarthritis Index(WOMAC)and Lysholm Knee Score were used to assess knee joint function;Berg Balance Scale(BBS)was used to assess balance function;the surface electromy-ography system was used to record the root mean square(RMS)of surface electromyography(sEMG)signals of the quadriceps and hamstring muscles during the squatting and standing of the affected knee joint,and the co-contraction rate(CR)was calculated;the adverse events during the treatment process of the two groups were compared.Results(1)VAS,WOMAC,Lysholm,and BBS scores:compared with those before treatment,VAS and WOMAC scores in both groups after treatment decreased significantly(P<0.05),while Lysholm and BBS scores increased significantly,and the differences were statistically significant(P<0.05).Compared with the control group,VAS and WOMAC scores in the observation group after treatment decreased significantly(P<0.05),while Lysholm and BBS scores were significantly higher,and the differences were statistically significant(P<0.05).(2)CR:compared with that before treatment,CR in the observation group after treatment decreased statistically,and the difference was statistically sig-nificant(P<0.05),while there was no statistically significant difference in CR in the control group after treatment(P>0.05).Com-pared with the control group,CR in the observation group after treatment was lower,and the differences was statistically significant(P<0.05).(3)Safety:no adverse events were observed in either group during treatment,and patients exhibited good compliance,in-dicating a high level of safety.Conclusion NEMEX training combined with semiconductor laser therapy can effectively improve pain,knee joint function,balance function,and muscle coordination and control around the knee joint of patients with KOA,which is worthy of clinical application.

Abstract Background To observe the effect of 10.6μm CO2 laser moxibustion (LM) on the fastest 15-meter walking time of patients with knee osteoarthritis (KOA). Methods 392 patients with KOA who met the inclusion criteria were randomized into the LM treatment group and sham LM control group (ratio 1:1). LM or sham LM was used to treat the affected part of the knee joint, 3 times a week for 4 weeks. Results In the LM group, the fastest walking time of 15 meters at Week 4 and Week 12 was shorter than that before treatment (all P < 0.05); In the sham LM group, there was no significant difference in the fastest walking time of 15 meters after treatment (all P > 0.05); The fastest walking time of 15 meters in CO2 LM group was shorter than that in sham LM group at Week 4and Week 12 (all P < 0.05). Conclusion CO2 LM can significantly improve the fastest 15-meter walking time of patients with knee osteoarthritis, and its curative effect can last for at least 8 weeks after treatment. The fastest 15-meter walking time can reflect changes in the walking ability of patients with knee osteoarthritis.

近年来,低强度激光针灸被广泛应用于治疗膝骨关节炎,其临床疗效与激光的各种参数以及治疗方法有关.通过检索中国知网、万方、维普、pubmed等中外文数据库,对近5年低强度激光照射治疗膝骨关节炎的临床研究进行综述.临床常被用作激光针灸照射治疗的低强度激光主要有半导体激光、氦氖激光以及二氧化碳激光.对不同研究中使用的的低强度激光的主要参数如波长、功率、功率密度以及研究方法如照射时间、疗程、选穴等归纳整理,为今后临床应用低强度激光治疗膝骨关节炎提供依据.