Objective To retrospectively analyze the efficacy and prognostic factors of surgery in patients with epilepsy secondary to ganglioglioma. Methods Retrospective analysis was conducted on the clinical data of patients epilepsy secondary to ganglioglioma who underwent surgery and pathologically confirmed to be ganglioglioma in Kunming Sanbo Brain Hospital from January 2014 to August 2020. Regular follow-up was performed. The risk factors affecting the prognosis of epilepsy were predicted by statistical analyzing the patient’s medical history, imaging manifestations, surgical resection scope, etc. Results There were 35 patients who underwent surgery and confirmed as ganglioglioma by postoperative pathology.The mean follow-up was 46.67 months. Among them, 28 patients achieved Engle Ⅰ class outcome, and 7 patients achieved Engle Ⅱ-Ⅲ class outcome.There was no recurrence of tumor after surgery. The clinical characteristics of 35 patients were analyzed by multivariate statistics. The disease course was statistically significant for the prognosis of epilepsy. Conclusion Ganglioglioma is prone to induce secondary epilepsy. Early diagnosis and early surgery are required for good prognosis. The disease course is an independent risk factor for the prognosis of secondary epilepsy to ganglioglioma.

脑深部电刺激(DBS)是治疗药物难治性震颤的主要手术方式，丘脑腹中间核(VIM)是手术首选靶点。近年来，丘脑底核后部(PSA)也逐渐应用于临床，并被认为是一个有潜力的靶点。2020年6—10月昆明三博脑科医院神经外科通过双侧单电极双靶点电刺激即VIM联合PSA-DBS对2例震颤患者进行了手术治疗，术后效果良好，证实了该手术的可行性，通过程控发现，PSA对震颤控制更理想。

目的 探讨脑膜血管瘤病(MA)致难治性癫痫的手术疗效.方法 回顾性分析2例经病理证实为MA患者的临床资料.病例1患者间歇期脑电图为正常脑电图,但患者存在明确临床发作;病例2患者同时并发灰质异位;二者均在术中皮层脑电监测下行病灶切除.结果 手术过程顺利,术后恢复良好,术后随访1年为Engle Ⅰ级,生活质量较前提高.结论 手术治疗MA引起的难治性癫痫有确定疗效.