目的 了解抑郁障碍青少年非自杀性自伤(NSSI)行为的特征以及其与生活事件、情绪症状的关系.方法 以112例青少年抑郁障碍患者为研究对象.使用青少年自我伤害问卷评估入组者NSSI情况并将其分为自伤组和无自伤组,使用自杀意念自评量表(SIOSS)评估自伤组自杀意念并将其分为伴自杀意念自伤组和不伴自杀意念自伤组.使用自制的一般情况调查表、青少年生活事件量表(ASLEC)、焦虑自评量表(SAS)、抑郁自评量表(SDS)对各组进行信息采集.结果 在入组的112名抑郁障碍青少年中,NSSI检出率为83.0％,其中,伴自杀意念的NSSI和不伴自杀意念的NSSI占比分别为88.2％和11.8％.自伤组SAS、SDS评分以及ASLEC总分及人际关系因子分均高于无自伤组(P<0.05),伴自杀意念自伤组ASLEC人际关系因子分及SAS、SDS评分均高于不伴自杀意念自伤组(P<0.05).结论 抑郁障碍青少年NSSI检出率高,NSSI的发生与负性生活事件及焦虑、抑郁情绪有关.

Objective To investigate the prevalence of behavioral problems and explore their relevant factors in children aged 6 ～ 11 years in Shandong province. Methods A total of 2 635 children aged 6 ～ 11 years from 16 cities of Shandong province were investigated by multi-stage stratified random sampling and assessed with Achenbach Child Behavior Checklist (CBCL) . Results The prevalence of behavior problems was 11. 1％ in children,and there was no statistically significant difference between 10. 8％ in boys and 11. 8％ in girls (P > 0. 05) . However,the differences of behavior problem prevalences among ages were significant (P < 0. 05) . Logistic regression revealed that father's hobby,family income,father's health,number of friends and quality of companion relationship might contribute to the behavior problems in children (P < 0. 05) . Conclusion The prevalence of behavioral problems in children is at a high level,which may be correlated with many factors with family factors as an important one.

Objective To explore the differences of clinical medications between children and adults with schizophrenia.Methods A total of 165 children and adolescents with schizophrenia and 165 adults with schizophrenia were selected and analyzed with medications and efficacv.Results There were risperidone,olanzapine,amisulpride,quetiapine and aripiprazole for the top 5 kinds of antipsychotic drugs as the single antipsychotics of medications in two groups.The dose of olanzapine in children and adolescents was significantly higher than that in adults (P ＜ 0.05).The ratio of combination of antipsychotics in children and adolescents was significantly higher than that in adults (P ＜ 0.05).The equivalent dose of risperidone combined with olanzapine in children and adolescents was significantly higher than that in adults (P ＜ 0.05).There was no difference for the outcomes of efficacy between two groups(P ＞ 0.05);and there was no difference for the outcomes of efficacy among different medication regimens between two groups(P ＞ 0.05).Conclusion It's similar for the status of antipsychotics between children and adults with schizophrenia and it is common for the combination of antipsychotics in the children.