目的 探讨基于患者自我报告结局(PROs)监测的远程管理在乳腺癌化疗患者中的应用效果.方法 2020年9月-2021年3月,采用便利抽样法选取郑州大学第一附属医院的134例乳腺癌化疗患者为研究对象,采用随机数字表法将其分为对照组和观察组,各67例.对照组给予常规护理,观察组在对照组基础上实施基于PROs监测的远程管理,为期3个月.比较两组生活质量和心理痛苦程度.结果 干预后,观察组生活质量各维度评分及总分均高于对照组,差异有统计学意义(P<0.05).干预后,观察组心理痛苦程度评分低于对照组,且心理痛苦程度评分>4分的患者例数少于对照组,差异有统计学意义(P<0.05).结论 基于PROs监测的远程管理可以改善患者的生活质量,缓解其心理痛苦程度,值得临床推广应用.
Objective:To investigate the influencing factors of second primary carcinoma (SPM) in patients with transitional cell carcinoma of bladder without distant metastasis.Methods:Patients diagnosed with transitional cell carcinoma of the bladder without distant metastasis were selected from the Surveillance, Epidemiology, and End Results (SEER) database from 1988 to 2016. The single factor analysis was conducted to select the factors influencing the occurrence of second primary cancer by using the cumulative incidence function (CIF) in the competitive risk model. Multivariate analysis was conducted by using the Fine-Gray model.Results:In total, 154 725 patients with transitional cell carcinoma of bladder without distant metastasis were identified. Multivariate analysis showed that marital status, age, race, gender, tumor invasion, radiotherapy, surgery and chemotherapy were the influencing factors of SPM ( P<0.05). Conclusions:Transitional cell carcinoma of bladder patients without distant metastasis should undergo risk screening for SPM to guide treatment, testing and follow-up plans.
目的 分析心理护理结合营养支持促进胃癌患者术后恢复效果.方法 入组我院收治的经病理学确诊并接受手术治疗的胃癌患者74例,随机均分为对照组、观察组,每组37例,分别实施术后常规护理、心理护理联合营养支持,比较不同护理模式对胃癌患者术后恢复的影响.结果 观察组肠鸣音恢复时间、首次排气时间、首次排便时间、总不良反应发生率均少于对照组,而汉密尔顿抑郁量表评分、汉密尔顿焦虑量表评分、生活质量评分(包括日常生活、健康、精神、支持、活动质量评分)均优于对照组(P均<0.05).结论 术后予以心理护理结合营养支持有利于胃癌患者术后早日恢复,并可改善患者生活质量,值得临床推广应用.