Total mesorectal excision (TME) is the gold standard for surgical treatment of rectal cancer. In contrast, whether to add lateral lymph node dissection (LLND) is still controversial worldwide. By reviewing the research literature related to lateral lymph node dissection for rectal cancer in recent years, this paper summarizes the current research status, controversies, surgical techniques and approaches of lateral lymph node dissection, in order to comprehensively discuss the application status of lateral lymph node dissection in rectal cancer, and the research worth in the future. To provide theoretical support and literature reference for the accurate application of lateral lymph node dissection in rectal cancer.
背景:透明质酸钠注射已用于许多肌肉骨骼疾病,包括膝关节骨性关节炎、肩周炎、类风湿性关节炎和其他肌腱软组织疼痛.目的:评价透明质酸钠与皮质类固醇治疗足底筋膜炎的效果.方法:65例足底筋膜炎患者随机分为2组,透明质酸钠组32例、皮质类固醇组33例.两组患者分别在超声引导下注射透明质酸钠2.5 mL(25 mg/2.5 mL)和复方倍他米松(二丙酸倍他米松5 mg,倍他米松磷酸钠2 mg),治疗间隔7d,共2次.分别在治疗前、治疗后1,3个月测量目测类比评分、足底筋膜厚度及AOFAS踝-后足功能评分.研究方案经青岛市市立医院伦理委员会批准,患者对治疗完全知情同意,并自愿完成治疗前后的评估、测试及随访.结果与结论:①治疗后1个月时与治疗前比较,两组目测类比评分、足底筋膜厚度下降,AOFAS踝-后足功能评分升高(P<0.05),其中皮质类固醇组目测类比评分显著低于透明质酸钠组(P<0.05);治疗后3个月与治疗后1个月时比较,两组治疗效果显著改善(P<0.05),两组之间评价指标差异无显著性意义(P>0.05);②皮质类固醇和透明质酸钠都能有效治疗足底筋膜炎,但短期1个月内皮质类固醇治疗效果更佳;为避免皮质类固醇治疗的潜在风险,透明质酸钠可以替代皮质类固醇治疗.