Objective To know the present iodine nutritive condition. Methods Salt iodine and urine iodine were tested by national standard methods. IRMA was used to examine newborn's whole blood (umbilical cord blood). Results (1) The qualified rate of iodine salt was within the national standard. (2) Three periods (phase, midterm, later period) urine sample of pregnant women's were collected, and the median of urine iodine was 231.40,212.44,192.25 μg/L, respectively, the late period's median was on a low side obviously; among the 3 111 urine samples, there were 516 samples with median of urine iodine 100 μg/L, which means some pregnant women and fetus were in the state of serious iodine deficiency; 728 women were sampled of their urine iodine in pregnant women,and the iodine level was highly related with TSH in newborns(r = 0.65, P 0.01). Conclusions The education of eliminating iodine deficiency disorders should be strongly increased, and it should focus on instruct pregnant women complementing iodine nutrition in late period of pregnancy, to insure the newborn's health.
[目的]为了2000年郑州市完成消除碘缺乏病阶段目标.[方法]采用<实现消除碘缺乏病阶段目标评估方案>规定的方法进行.[结果]碘盐生产(批发)单位、销售点、居民户三级碘盐合格率分别为99.0%、99.0%、96.71%;尿8-10岁儿童甲状腺肿大率,触诊为3.48%、B超法为4.15%;8-10岁儿童尿碘中位数282.1μgg/L;健康教育测试,五年级学生及家庭主妇知识及格率为99.33%、98.07%,行为正确率为84.67%、100%.[结论]郑州市2000年达到消除碘缺乏病阶段目标.
尽管治疗方法不断改进,如今对百日咳的控制还主要依赖于菌苗预防[1],目前世界各地除日本外均在使用全细胞百日咳菌苗,该菌苗能够提供保护水平的免疫力,在百日咳的预防方面起到了很大的作用,但由于接种后毒性反应较重,异常反应的发生率较高,特别对极少数儿童可诱发严重的神经系统反应,其安全性引起了人们的普遍关注.