帕金森病的冻结事件严重降低患者的生活质量,增加致残率。可穿戴设备的兴起在帕金森病等慢性病领域开拓了广泛的应用前景。本文对可穿戴设备在帕金森病冻结步态领域的应用进行综述,为探讨冻结步态可能的运动学机制,量化冻结步态评估,完善冻结步态的管理提供有力的依据。
脑卒中是神经内科的常见病、多发病,具有高发病率、高患病率、高病死率、高致残率的特点,目前已成为全球第二大死亡原因,成为世界性的健康问题.目前,急性缺血性卒中的临床治疗策略主要有静脉溶栓和机械取栓疗法.然而这些策略并不能使患者免受缺血性损伤和功能障碍.因此,治疗上应进一步关注提高缺血区周围神经元的存活率和神经功能的恢复.本文回顾了缺血性脑卒中的发病机制及缺血性脑卒中后神经功能恢复药物的研究进展.
Parkinson's disease (PD) decreases the quality of life of the affected individuals. The incidence of PD is expected to increase given the growing aging population. Motor symptoms associated with PD render the patients unable to self-care and function properly. Given that several drugs have been developed to control motor symptoms, highly sensitive scales for clinical evaluation of drug efficacy are needed. Among such scales, the objective and continuous evaluation of wearable devices is increasingly utilized by clinicians and patients. Several electronic technologies have revolutionized the clinical monitoring of PD development, especially its motor symptoms. Here, we review and discuss the recent advances in the development of wearable devices for bradykinesia, tremor, gait, and myotonia. Our aim is to capture the experiences of patients and clinicians, as well as expand our understanding on the application of wearable technology. In so-doing, we lay the foundation for further research into the use of wearable technology in the management of PD.