Цель исследования. Установить границы и степени ускоренных и замедленных вариантов старения мужчин и женщин г. Красноярска и Красноярского края с целью использования данного показателя, как маркера в оценке физического здоровья. Материалы и методы. На основе антропометрических данных определена скорость старения по методике А.Г. Горелкина и Б.Б. Пинхасова (2008). Для разбиения выборки на интервалы, соответствующие различным вариантам скорости старения, использован центильный анализ по А.А. Ушакову (2008). Результаты. Использование центильного анализа позволило определить границы нормальных значений коэффициента скорости старения для жителей Красноярского края от 0,980 до 1,199 у женщин и от 0,960 до 1,209 у мужчин. Значения данного коэффициента, выходящие за границы нормальных значений, разбиты на центили, характеризующие первую, вторую и третью степени замедленного и ускоренного вариантов старения. Заключение. Коэффициент скорости старения, характеризующий биологический возраст человека, как у женщин, так и у мужчин имеет высокую вариабельность значений, что показывает необходимость ранжирования значений данного коэффициента на степени. Данный показатель, отражающий все биологические процессы, происходящие в организме, в совокупности с другими параметрами может быть использован для оценки физического здоровья населения.

The aim of the research. To identify ethnic features kefalometric parameters and head shape of the contemporary women of Eastern Siberia compared to the similar data of the European part of Russia. Materials and methods. The study involved 239 women Europeoids and 406 women Mongoloids. Was conducted kefalometria followed by determination of the cephalic index and head shape. Results. Larger head size is typical for the Mongoloid population compared to Europeoids. In the temporal aspect (300 years) the decrease of cephalic index in Europids is typical. Conclusion. Our results support the view of T.I. Alexeeva about common for the entire Russian population anthropological type on cephalic index mezokefalia.

Aim. To develop a methodology for individual, group, regional and population health estimation. Methods. Offered methodology includes physical health assessment and assessment of morphologic and functional condition of organ systems in a healthy human. Physical health assessment was performed in 808 young males aged 17-21 years in the city of Krasnoyarsk. Anthropometry, body mass index calculation, Tanner maturation index, ageing speed coefficient calculation by B.B. Gorelkin and A.G. Pinhasov, bioelectrical impedance analysis and statistical analysis were performed. Results. Youth males had a height of 176.87±0.26 sm, body weight of 69.23±0.45 kg. According to calculated body mass index, healthy weight was found in 71.41% males, 12.75% were overweight, 3.96% were obese, 11.88% were underweight. Shoulders and pelvis diameters were assessed as 37.01±0,11 and 27.72±0.09 sm respectively. Tanner maturation index calculation has shown that 54.83±1.20% males were andromorphous, the others had different types of gender inversions: 18.69±0.94% were hynecomorphous, 26.49±1.07% were mesomorphous. Ageing speed coefficient calculation has revealed the discrepancy of calendar and biologic age (the latter was higher) in all hynecomorphous young males, meaning that hynecomorphism can be estimated as a predictor of early ageing and can be used in complex health assessment. The core of the offered methodology for population health estimation is the health assessment on all stages of ontogenesis, including all levels from organism to molecular, that would allow to develop the standards for health assessment and assessment of morphologic and functional condition of organ systems. Conclusion. The listed methods would allow to estimate organism’s morphologic and functional condition, and revealed physical development abnormalities would allow to correct them timely before the clinical onset of any diseases.

The purpose of the research is to study diameters of vertebrobasilar system arteries at patients with neoplasms of cerebellopontine angle 56 women with tumors of this localization are surveyed with usage of spiral computer tomography with angiographic program. It is revealed that the augmentation of diameters of vertebral and all cerebellar arteries on the tumor part is characteristic for these patients. The large sizes of basilar artery, vertebral, back and anteroinferior cerebellar arteries on the lesion part are registered at patients with vestibular schwannomas. The augmentation of diameters of basilar and anteroinferior cerebellar arteries on the tumor part became perceptible at women with meningiomas.

We investigated 56 patients with vestibular schwannomas. We researched the cerebral blood flow velocity in the vertebral and basilar arteries. We evaluated the reactivity of cerebral blood flow with use the hypercapnic and hypocapnic functional tests. The average hypercapnic reactivity in patients with vestibular schwannomas in the vertebral artery amounted to 16,73%, in the basilar artery — 21,59%. 35 (62,5%) patients with vestibular schwannomas had the hyporeactivity and 5 (8,92%) patients had areactivity of vertebral artery. The data obtained showed the risk of development of pathological cerebrovascular reactions and ischemic disorders.

Anthropometric examination of 306 patients with chronic urethrogenic prostatitis aged from 21 year till 35 years is conducted. It is statistically authentically established (р

Based on the analysis of the results to assess the physical status of the Eastern Siberia population from the common list of indicators were identified the biomarkers that we evaluated as indicators of physical health. It is presented a list of biomarkers for assessing the physical status of the person depending on the period of its ontogenetic development cycle. It was developed the classification of biomarkers for their subsequent use in the studies.

In modern medical science the studying of human health is reoriented on individual principle. The severe need in knowledge of individually-typological features of organism is demanded by the clinical anthropology which purpose is revealing and studying of the constitutionally determined patterns of manifestation. In connection with the purpose of the present research was the definition of constitutional peculiarity of women with hyperplastic diseases of endometrium, hysteromyoma, during in perimenopause period. During work 157 women of II period of mature age are surveyed. Complex anthopometrical investigation of women with hyperplastic processes of endometrium and hysteromyoma is conducted. Constitutional peculiarity of women of II period of mature age with hyperplastic processes endometrium, hysteromyoma are presented.

There was described a way of risk level prognosing of fibrosis development in epidural space after surgical resection of lumbar intervertebral disks, including microdisectomy for each patient with diskogenic compression syndromes at pre-surgery period.