The arterial hypertension complicated by development of a brain stroke is one of the main reasons of population disability. In the article there are presented features of circadian blood pressure profile and arterial stiffness at patients with an ischemic stroke with uncorrected arterial hypertension. It is established that the increased variability of arterial pressure, pulse wave velocity and central aortal pressure are starting factors of ischemic stroke development and these parameters may be used as predictive indicators of a functional outcome of acute ischemic stroke.

Strokes are major health and social problem due to their high share in the structure of morbidity and mortality, as well as significant indicators of temporary work loss and primary disability. In connection with that regional centers, specialized sanatoriums (including the Kursk region) are established to treat strokes. Particularly relevant is the study of endothelial function in cases of patients with ischemic stroke, as the main pathogenetic mechanisms of hypertension and atherosclerosis, since the insufficient study of the problem. The aim of our study is to determine the dynamics of ultrasound signs of endothelial dysfunction in patients with ischemic stroke against the background of the ischemic heart disease and high blood pressure in the acute period, and at the stage of rehabilitation in the sanatorium. In our paper we present the prospects of an easy affordable ultrasonic cuff test to assess endothelial dysfunction in cases of patients with ischemic stroke. In the analysis of the sample over time there is a tendency to an improvement of endothelial dysfunction, which, however, is not sufficient, that is the rea son to use modern medical therapy and rehabilitation measures to improve endothelial function.