Objective To investigate the effect of specialized nursing intervention on maintenance hemodialysis patients with diabetic nephropathy（DN）. Methods 68 patients with DN maintenance hemodialysis admitted to Yancheng First People’s Hospital from January 2017 to October 2021 were selected as the study subjects, and were divided into control group and observation group according to random number table method, with 34 patients in each group. The control group used routine nursing, and the observation group adopted special nursing intervention on the basis of the control group. The effect of blood glucose control, complications of vascular access and nursing satisfaction were compared between the two groups. Results The complication rate of vascular access in the observation group（2.94%） was lower than that in the control group（23.53%）, and the nursing satisfaction rate（97.06%） was higher than that in the control group（70.59%）, the difference was statistically significant（P＜0.05）. After nursing, the blood glucose level of observation group was lower than that of control group, the difference was statistically significant（P＜0.05）. Conclusion Specialized nursing intervention can reduce the occurrence of vascular access complications in DN maintenance hemodialysis patients and improve the effect of blood glucose control.

目的:观察液压扩张法联合贝前列素钠片对动静脉内瘘成熟的影响.方法:选择2019年01月—2020年12月于我院肾内科行动静脉内瘘术的患者100例,随机分为对照组和联合干预组.对照组采用常规端侧吻合动静脉内瘘术,术后采用常规治疗方法及术后护理;联合干预组术中在常规端侧吻合动静脉内瘘术基础上加用液压扩张法,术后口服贝前列素钠片,每次1片,每日3次,共服药8周.观察两组术后8周患者吻合管内径及血流量、动静脉内瘘成熟不良发生率、术后并发症发生率及超敏C反应蛋白水平的变化.结果:8周后,综合干预组吻合管径及内瘘血流量明显高于对照组(P<0.01),综合干预组内瘘成熟不良发生率及并发症发生率明显低于对照组(P<0.01),超敏C反应蛋白水平亦明显低于对照组(P<0.01).结论:液压扩张法联合贝前列素钠口服对于促进患者内瘘成熟具有良好的作用,值得临床推广.