目的 系统评价中国儿童抽动障碍预后的影响因素.方法 计算机检索PubMed、EM base、T he Cochrane Library、Web of Science、CBM、维普、万方以及中国知网数据库,全面收集中国儿童抽动障碍预后影响因素的观察性研究,检索时限均为从建库至2022年4月.由两名研究员独立进行文献筛选、资料提取,并选用纽卡斯尔-渥太华量表(NOS)进行纳入文献的质量评价.采用RevMan 5.4软件进行Meta分析.结果 检索文献共3572篇,最终纳入10篇,包含2项病例对照研究和8项队列研究,共包含1699例中国抽动障碍患儿.Meta分析结果显示,精神、神经疾病家族史[OR=3.17,95％CI(1.51,6.66)]、共患病[OR=2.55,95％CI(1.68,3.87)]、病情反复频数[OR=3.65,95％CI(2.06,6.48)]、病情严重程度[OR=1.52,95％CI(1.19,1.94)]、反复呼吸道感染[OR=1.33,95％CI(1.22,1.44)]、家庭环境[OR=3.00,95％CI(1.50,5.99)]是影响中国儿童抽动障碍预后的危险因素.结论 精神、神经疾病家族史、共患病、病情反复频数、病情严重程度、反复呼吸道感染、家庭环境与中国儿童抽动障碍预后不佳相关.
新型冠状病毒(简称"新冠")感染自爆发以来,各国经济发展和社会稳定均受到不同程度的影响.新冠感染患儿少见危重症,无症状感染者比例高,多数患儿临床症状轻、预后好.中医药在新冠疫情中充分发挥整体审查、辨证论治和三因制宜的独特优势,在疫情防控中扮演了重要角色.该文从儿童新冠感染的中医认识、中医治疗及预防3个方面对儿童新冠感染的中医药防治研究进展进行综述.
Review question / Objective: P:Children under the age of 18 with tic disorders, no restrictions on gender or ethnicity of participants.I:Presence of a certain factor affecting prognosis C:Absence of a certain factor affecting prognosis
Review question / Objective: Patients who meet the clinical diagnostic criteria of Gilles de la Tourette syndrome (DSM-IV/DSM-V) are included, regardless of race, sex, age, etc. Deep brain electrical stimulation for the treatment of Tourette's syndrome, with no limit on the specific procedure and duration of stimulation. Randomized controlled trials were selected, the language was limited to Chinese and English, and there were no restrictions on race, age, sex and so on. The main outcome indicators were the Yale Global tic severity scale score. Other outcome indicators included the Modified Rush Video Rating Scale score, Beck's Depression Inventory score, State-Trait Anxiety Inventory score, Gilles de la Tourette Syndrome-Quality of Life Scale score and Yale Brown Obsessive Compulsive Scale score. Information sources: The Cochrane Library, Embase, Web of Science, MEDLINE and four Chinese electronic databases: China Biomedical Literature Database (CBM), China knowledge Network (CNKI), VIP Chinese Technical Journals Database (VIP), Wanfang Digital Database.The search time limit is from the self-built database to July 03, 2022.
