According to previous studies, gastroesophageal reflux disease is associated with a high risk of cardiac arrhythmias. In addition, the drugs used to treat the disease, according to the literature, may promote arrhythmias. In this connection, the article gives the heart rate variability indexes obtained from the analysis of Holter monitoring data taken from 71 patients experiencing gastroesophageal reflux disease, estimates the correlation of these indicators with the indicators of the state of the pH in the esophagus.

The article gives the heart rate variability indexes obtained from the analysis of Holter monitoring data taken from 57 patients experiencing Gastroesophageal Reflux Disease, estimates the correlation of the indexes with the age, sex and the presence of the signs of of esophageal mucosa alteration or the heart rhythm disorder.

The question of the combination of the gastro esophageal reflux disease (GERD) with the coronary heart disease of the same patient has the particular applicability. The study includes 235 patients aged 43-86 having the chronic form of the coronary heart disease. During the study it was found out that 14,9% of the coronary heart disease have the signs of the GERD. It is noted that the combination of the GERD and coronary heart disease causes the mutual increase of the clinical manifestations of the diseases and their transformation. It is importaint to consider this fact when such patients are being examined and treated

The results of study of the prevalence of gastroesophageal reflux disease are presented. Revealed its high prevalence among the residents of Saransk. A comparative analysis of symptoms by sex and age of the respondents was conducted.

In the article are shown the results of the study being the first of the detailed population-based study of the prevalence of gastroesophageal reflux disease in Russia based on the reflux questionnaire (Mayo Clinic). The high prevalence of gastroesophageal reflux disease was determined among the inhabitants of Saransk. We made the comparative analysis of the symptoms of the disease with regard for sex and age of the respondents.