Primary lymphoma of the heart (non-Hodgkin's lymphoma primarily of B-cells affecting first the heart and pericardium) is a rare disease which accounts for 1.3-2.0% of all primary tumors of the heart. A case is reported of a 43-year-old male patient with a cardioverter-defibrillator implanted at the age of 38 years for management of ventricular tachycardia paroxysms and AB-block of the second-third degree. The patient also had hypertrophic cardiomyopathy, moderate pressure gradient on the pulmonary artery valve and pericardial effusion. Later he had two cardiac tamponades (serous punctuate). From the age of 42 years breathlessness, right ventricular wall thickness, right heart pressure and pulmonary artery pressure aggravated. The patient has undergone ballon plastic surgery of the pulmonary artery valve. At the age of 43 computed tomography detected massive tumor of the heart and mediastinum first diagnosed as sarcoma but later specified as lymphoma. Endobronchial biopsy specimens contained the tissue of diffuse large B-cell lymphoma, the liver and lymph nodes were also involved. After the first course of effective polychemotherapy (CHOP) the patient died of mesenterial thrombosis. Diagnostic difficulties and problems of treatment policy are discussed.

The data of examination and treatment were given for a 20-year-old patient with the long history of syncope, in whom the short QT interval syndrome was observed and ventricular fibrillation was induced in the course of endocardial electrophysiological study during the programmed pacing, which was an indication to implantation of cardioverter-defibrillator.

It has been conducted retrospective analysis of antiarrhythmic drugs efficacy in patients with non-coronarogenic ventricular arrhythmias after performing electrophysiological study and in some patients – radiofrequency catheter ablation, taking into account nosology and the mechanism of arrhythmia, and initial characteristics of heart rate variability.

In 1977, Fontaine et al. were the first to report on arrhythmogenic right ventricle dysplasia as one of the cardiopathy types that affects mainly the right ventricle [1]. This pathology is characterized by adipose myocardium dysplasia of the apex and of the right ventricular outflow tract (RVOT). Ventricular tachycardia (VT) with the morphology of left His bundle block and of left His bundle anterior branch block is caused by this pathology. It has been frequently observed in young patients and poses a risk for sudden death. The efficiency of radiofrequency ablation (RFA) to treat VT associated with right ventricle arrhythmogenic dysplasia remains unclear. Accordingly, we present a case report of an effective "cooled" RFA in an RVOT tachycardia patient.