Aim. To investigate the relationship of soluble ST2 (sST2) to acute heart failure (AHF) and compare the predictive value of sST2 and brain natriuretic peptide in patients with ST-elevation myocardial infarction (STEMI).Material and methods. In 136 STEMI patients, the serum sST2 concentration was determined during the first 24 hours of hospitalization. We assessed levels of sST2, N-terminal pro-brain natriuretic peptide (NT-proBNP), incidence of Killip class II-IV AHF during hospitalization, myocardial necrosis biomarkers, parameters of complete blood count and biochemical blood tests, the incidence of cardiovascular diseases and risk factors. The predictive value of sST2 for AHF development was assessed using logistic regression. ROC analysis was performed. The areas under the ROC curve were compared for sST2 and NT-proBNP. The cut-off sST2 value was determined for predicting AHF.Results. The mean sST2 level was 43,4 (33,6-73,9) ng/ml. During the followup period, AHF was diagnosed in 54 people (39,7%). The prevalence of AHF in the 1st, 2nd and 3rd tertiles of sST2 was 15,6%, 33,3% and 69,7%, respectively. The NT-proBNP levels were 319 (128-1072) pg/ml, 430 (147-1140) pg/ml and 1317 (533-2386) pg/ml. The predictive value of 3rd sST2 tertile was retained adjusted for age, sex, NT-proBNP, troponin T, creatine phosphokinase-MB, high-sensitivity C-reactive protein, hemoglobin, blood glucose, left ventricular ejection fraction. The areas under the ROC curves for sST2 and NT-proBNP were comparable (0,828 and 0,733, respectively; p=0,056). The cut-off sST2 value was 64 ng/ml, above which the odds ratio of AHF was 11,1 (95% confidence interval, 4,7-26,1.Conclusion. An increase in blood sST2 is associated with an increase in AHF (Killip II-IV) prevalence in hospitalized patients with acute STEMI. Soluble ST2 has an independent predictive value for AHF in STEMI, comparable in strength and predictive model quality to NT-proBNP. The cut-off sST2 value for AHF (>64 ng/ ml) was calculated, which provides an optimal balance of sensitivity, specificity and accuracy of the prognostic model. These data support the potential value of sST2 as a biomarker of AHF in STEMI.

The article describes the demographic situation, the status of neonatal, children cardiological and cardiosurgery cares in the Buryat Republic. The information gathered by main non-staff experts of appropriate specializations proves the necessity of cardiosurgical care to the children population, identifies the structure of heart defects, the volume of cardiosurgical care provided to patients with congenital heart diseases in the region and outside of the region during from 2013 to 2015, preoperative and postoperative mortality. In addition, the article represents diagnostic capabilities of one of the largest medical institutions of the Buryat Republic as a potential station for delivery of cardiosurgical care for patients with congenital anomalies of cardiovascular system and suggests ways to optimize the care of children with congenital heart disease.

The article presents the results of the analysis of gender differences in patients hospitalized with diagnosis "acute coronary syndrome". The most common risk factor of acute coronary syndrome among men was smoking. The most common risk factors of acute coronary syndrome among women were general obesity, abdominal obesity, arterial hypertension and diabetes. Men significantly more frequently had multiform coronary disease with predominantly proximal level of the pathological process in comparison with women. Men are more often subjected to invasive treatment of acute coronary syndrome.

Summary. ? e aim of the study was the comparative analysis of the clinical status of men and women who underwent coronary artery bypass surgery. It is shown that among women with coronary heart disease overweight, obesity, diabetes mellitus and hypertrophy of the leD ventricle were revealed more oD en, than among men. Also the features of coronary atherosclerosis in women were the presence of three vascular lesions of coronary arteries with the degree of stenosis up to 50%. Key words: ischemic heart disease, coronary artery bypass graD ing, women.G‚†“†‘‚Ÿ‰S†‚µ ƒ‰‹„• ‘†„Ÿˆ„ ‡€ˆŒ’ SŽ„‰ ƒ‰S‹„ Ž ’‰-Ÿ‰ˆ‚‚ …„’–ˆsž ‚›‰ƒ‚Ÿ‰S†„µ …„’‰‡ˆ–œ S‰†•N€ ("&s). ¾„‹ “—‰ …„’‰‰ 30 ’‰‹ €„†‹„†„†„ˆ€†ˆ„‰ ›“ˆ‹‚†„Ž€ˆ‚‰ (°*+) ŒŽ’Œ‰‹SŒ ˆ€‚…„’‰‰ Ÿ€S‹„ Žs‘„’ˆŒ‰ƒ„µ ž‚†“†‘‚-Ÿ‰S†„µ „‘‰†€N‚‰µ Ž„ ƒˆ„‘‚ž †’‚ˆ‚†€ž ”„SS‚‚ ‚ ‡€ †“-…‰—„ƒ [6]. °ˆ€’‚‡ †‰‡“’–‹€‹„Ž ‘„†€‡sŽ€‰‹, Ÿ‹„ Ž€—ˆ„µ „…’€S‹–œ ‚SS’‰•„Ž€ˆ‚µ ŒŽ’Œ‰‹SŒ „‘†‰•‰’‰ˆ‚‰ ‹€†‹‚†‚ ’‰Ÿ‰ˆ‚Œ ˆ‰†„‹„†sž †€‹‰‘„†‚µ ‘€N‚‰ˆ‹„Ž, † Ÿ‚S’“ †„-‹„†sž „‹ˆ„SŒ‹SŒ —‰ˆO‚ˆs [1]. #S‹– ƒˆ‰ˆ‚‰, Ÿ‹„ “ —‰ˆ-O‚ˆ ‘„ S†€Žˆ‰ˆ‚œ S ƒ“—Ÿ‚ˆ€ƒ‚ …„’‰‰ Žs†€—‰ˆ€ S‚ƒ-‘‹„ƒ€‹‚†€ ‡€…„’‰Ž€ˆ‚Œ ‘†‚ €ˆ€’„‘‚Ÿˆsž ‚‡ƒ‰ˆ‰ˆ‚Œž Ž †„†„ˆ€†ˆsž €†‹‰†‚Œž [7]. ”€ˆ‰‰ ‘†„Ž‰•‰ˆˆs‰ ‚SS’‰•„-Ž€ˆ‚Œ ‘„†€‡€’‚, Ÿ‹„ ‘†‚ˆ€•’‰—ˆ„S‹– † —‰ˆS†„ƒ“ ‘„’“ ŒŽ’Œ‰‹SŒ ˆ‰‡€Ž‚S‚ƒsƒ €€†‹„†„ƒ †‚S†€ …„’‰‰ ŽsS„†„µ ‘„S‘‚‹€’–ˆ„µ ’‰‹€’–ˆ„S‹‚ ‚ Ÿ€S‹sž „S’„—ˆ‰ˆ‚µ ‘„S’‰ †„†„ˆ€†ˆ„‘„ ›“ˆ‹‚†„Ž€ˆ‚Œ [8]. •‰ƒ ˆ‰ ƒ‰ˆ‰‰ Ž ‘„S’‰•-ˆ‚‰ ‘„•s „‹ƒ‰Ÿ€‰‹SŒ †„S‹ †„’‚Ÿ‰S‹Ž€ —‰ˆO‚ˆ, ‘‰†‰ˆ‰S-›‚ž „‘‰†€N‚‚ †„†„ˆ€†ˆ„‘„ ›“ˆ‹‚†„Ž€ˆ‚Œ. "‡Ž‰S‹ˆ„, Ÿ‹„ Ž †€‡ˆsž ’‰Ÿ‰…ˆsž “Ÿ†‰—•‰ˆ‚Œž S“O‰S‹Ž“œ‹ ‡ˆ€Ÿ‚-‹‰’–ˆs‰ †€‡’‚Ÿ‚Œ Ž ‘„•ž„•‰ † ž‚†“†‘‚Ÿ‰S†„ƒ“ ’‰Ÿ‰ˆ‚œ —‰ˆO‚ˆ, S‹†€•€œO‚ž "&s [1]. “•ˆ€†„ ‘†‚ ŽS‰ƒ ƒˆ„‘„-„…†€‡‚‚ Ž„‘†„S„Ž, Ž„‡ˆ‚†€œO‚ž ‘†‚ †‰›‰ˆ‚‚ A‹„µ ‘†„…’‰ƒs, S„Ž†‰ƒ‰ˆˆ€Œ ‘„‡‚N‚Œ S‘‰N‚€’‚S‹„Ž Ž †„†„-ˆ€†ˆ„µ ž‚†“†‘‚‚ ‹€†„Ž€, Ÿ‹„ —‰ˆS†‚µ ‘„’ ˆ‰ •„’—‰ˆ S’“—‚‹– ‘„Ž„•„ƒ •’Œ „‹†€‡€ „‹ „‘‰†€N‚‚, ‰S’‚ ‚ƒ‰œ‹SŒ ‘„†€‡€ˆ‚Œ † †‰Ž€S†“’Œ†‚‡€N‚‚ ƒ‚„†€†•€.¾ ”‰S‘“…’‚†‰ &“†Œ‹‚Œ „‘‰†€N‚‚ †„†„ˆ€†ˆ„‘„ ›“ˆ‹‚-†„Ž€ˆ‚Œ ˆ€Ÿ€’‚ Žs‘„’ˆŒ‹–SŒ S 2006 ‘„•€. %„•€Ž’ŒœO‰‰ …„’–›‚ˆS‹Ž„ ‘€N‚‰ˆ‹„Ž ‘†‰•S‹€Ž’‰ˆ„ ƒ“—Ÿ‚ˆ€ƒ‚, „•ˆ€†„ Ž ‘„S’‰•ˆ‚‰ ‘„•s „‹ƒ‰Ÿ€‰‹SŒ “Ž‰’‚Ÿ‰ˆ‚‰ Ÿ‚S’€ G€†€†‹‰†‚S‹‚†€ …„’–ˆsž ‘„ ˆ€’‚Ÿ‚œ €€†‹„†„Ž †‚S†€ "&s ‚ ‘€N‚‰ˆ‹„Ž-—‰ˆO‚ˆ. "SS’‰•„Ž€ˆ‚µ A€€‰†‹‚Žˆ„S‹‚ †„-†„ˆ€†ˆ„‘„ ›“ˆ‹‚†„Ž€ˆ‚Œ “ —‰ˆO‚ˆ S "&s Ž S†€Žˆ‰ˆ‚‚ S ƒ“—Ÿ‚ˆ€ƒ‚ Ž &“†Œ‹‚‚ ˆ‰ ‘†„Ž„•‚’„S–, Ÿ‹„ ŒŽ‚’„S– „Sˆ„Ž€ˆ‚‰ƒ •’Œ ‘†„Ž‰•‰ˆ‚Œ ˆ€S‹„ŒO‰‘„ ‚SS’‰•„Ž€ˆ‚Œ.

The purpose of research was the comparative analysis of spreading renal disease and its association with factors of cardiovascular risk in 205 patients of mongoloid and european races, suff ering from hypertonic disease. It has been shown that among patients of mongoloid race increased level of creatinine and rate of glomerular fi ltration 30-59 ml / min/1,73m2 were noted more rarely. Th e interethnic diff erence in correlation of chronic renal disease and factors of cardiovascular risk has been obtained.

The authors consider surgical revasculization to be the method of treatment contributing to significant increase of tolerance to physical load in patients with coronary heart disease

In the article the brief review of literature devoted to coronaryangiography is given. The own data about guantity of executed coronaryangiography, the struck of coronary arteries and complications are submitted

The authors studied risk factors and clinical-anatomic peculiarities of combined atherosclerotic lesion of coronary and main arteries of lower extremities