Complications after implantation are noted at different follow-up periods [5, 6, 28, 33, 36, 38, 43]. It is known that the frequency of implant rejection varies, on average, from 3% to 35%, and an unoccupied inflammatory process leads to the loss of a dental implant [12].Currently, the development of peri-implantitis is more studied. However, as a result of clinical cases, the development of the inflammatory process from 6 months to 3 years after implantation was revealed. It has been established that during surgical procedures it is necessary to carry out a complex of prophylactic measures that make it possible to prevent the possibilities of inflammation developing [32].Reasonable and clinical application of the treatment-and-prophylactic rehabilitation complex in patients, taking into account individual characteristics in each clinical case, is relevant. So, the task of developing and justifying a complex of therapeutic measures, which allows to obtain a large number of complications during dental implantation, is not only medical, but also social.

We studied the stress-strain state of the bone tissue and maxillary full-arch fixed implantretained denture. Load was applied to the anterior (150 N) and posterior (250 N) parts of the denture supported by 6 or 4 implants, including zygomatic ones and placed by on-all-4 treatment technology. The obtained stress values in the bone tissue, implants, and denture show a large strength margin of structural materials. At the same time, the bone strength values were low, especially around the zygomatic and distal implants of all-on-4-implants-supported dentures when the posterior part of the denture was under load.

For evaluation of the efficiency of bone substitute, nanostructurized Gamalant-paste-FORTEPlus was placed into a mandibular defect in rats. Bone tissue reparation was evaluated after 30 days by histological methods under a microscope. Use of bone substitute in experimental mandibular defect ensured more complete and rapid restructuring of the bone tissue in comparison with the control (natural healing).

The results of the complex treatment of patients with generalized chronic periodontitis, including photodynamic therapy and microcurrent electrical stimulation are presented. Analysis of the immediate and long-term results showed the effectiveness of the impact of this treatment on cerebral hemodynamics and autonomic balance in these patients.

The authors describe a new method for the rehabilitation of the patients in the early postoperative period following dental implantation in the mandible that was accompanied by the development of traumatic mandibular nerve neuropathy. All the patients were treated using standard therapy. Those in the study group underwent in addition electrical stimulation based on the ciliary reflex system with the application of bipolar pulsed currents generated in a Miomodel-10 device. The electrical stimulation based on the ciliary reflex system is designed to influence extracranially the peripheral component and the nuclear apparatus of the trigeminal nerve. The reflex arc of the ciliary reflex involves afferents of the trigeminal nerve, efferents of the facial nerve, nuclei of these cranial nerves, and neurons of reticular formation of the brain stem. Electrical stimulation based on the ciliary reflex system includes symmetric application of bipolar pulsed currents to the region of projection of the trigeminal nerve I, II, and III branches and Gasseri ganglion that gives rise to the first sensitive neurons whose peripheral dendrites form three major branches of the trigeminal nerve, viz. ophthalmic nerve (n. ophthalmicus), maxillary nerve (n. maxillaris), and mandibular nerve (n. mandibularis). In other words, electrical stimulation based on the ciliary reflex system acts extracranially over a large area, eliminates pain syndrome by acting through neural conductors, improves blood circulation in these regions, and thereby facilitates the recovery of conductance through the nervous fibers of the mandibular nerve. These findings indicate that the application of bipolar pulsed currents by the local method and by electrical stimulation based on the ciliary reflex system promotes normalization of the functional activity of the mandibular nerve, activates microcirculation and neuroplastic processes, exerts analgesic, anti-inflammatory, regenerative, and neurotrophic actions.