Free radicals have taken a firm place among the explanatory principles of the onset and development of tumors. Unambiguous ideas about the role of these highly active agents in carcinogenesis have not yet been obtained. The experimental results are contradictory, often the opposite. The field of study of the value of the activity of antioxidant systems based on the results obtained is no less controversial. In this regard, the urgent problem is the need to prescribe antioxidants in oncology. Antitumor effects of antioxidants are being questioned in many works, which brings to the forefront the appropriateness and adequacy of their appointment. The ambiguous role of free radicals in carcinogenesis determines the development of therapeutic strategies based on the precise modulation of oxidative processes.

The article presents the results of an experiment aimed to determine the antioxidant activity of bee products, such as alcoholic extracts of propolis and large wax moth larvae, as well as water extraction from a pharmaceutical form suppositories – containing these extracts. The results give evidence of preservation of the antioxidant activity of the components in their joint entry in the drug.

Many diseases and influence of environmental negative factors create favorable conditions for the violation of the free-radical oxidation. There is a need for the use of antioxidants with preventive and therapeutic purposes to maintain the velocity of the free-radical oxidation at an optimal level. In this connection there is an active search for antioxidants among herbal medicines and apiculture products.

The article presents the results of Coenzyme Q and L-carnitine therapy of 129 men from infertile couples. The antioxidant status was assessed by registration of chemiluminescence and by colorimetric method according to changes in the color of ABTS chromogen. The antioxidant activity of drugs in model systems in vitro and in vivo has been established.

Before and after administration of L-Carnitine Tartrate to patients with idiopathic patospermia, the analysis of the spermograms has been made and prooxidant as well as antioxidant status of the ejaculate has been evaluated. It is established that the use of LCarnitine Tartrate is accompanied by normalization of balance of oxidation and antioxidation processes in sperm and its fertilizing ability.