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1Modelling of Diagnosis of Acute Salpingo-Oophoritis Based on the Most Informative Parameters of Cellular and Humoral Immunity on the Systemic Level

N.М. Аgarkov,E.N. Korovin,O.I. Оkhotnikov,А.V. Ivanov, Yu.А. Blinkov, А.V. Golikov,Т.I. Subbotina,А.S. Kulabukhov,I.V. Budnik

2019Voprosy ginekologii, akušerstva i perinatologii（2019）引用：1

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2Assessment of Treatment Efficacy in Patients with Genital Herpes in Terms of Electrical Properties of Tissues at Specific Acupuncture Points Using a Fuzzy Mathematical Model

N. A. Korenevskiy,M. I. Lukashov,V. V. Dmitrieva, E. V. Pis’mennaya,A. V. Ivanov,D. I. Kicha,T. I. Subbotina, A. I. Kolesnik

The classification of the stages of genital herpes is discussed on the basis of readings from acupuncture points P7 and VC7, which change their energy characteristics as the activity of genital herpes increases. Inclusion of reflex therapy methods to traditional treatment schemes was found to promote decreases in the duration of clinical episodes. A scheme for a standalone instrument based on a microcontroller with low energy consumption able to monitor the energy status of acupuncture points is described.

2018Biomedical Engineering（2018）

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3Дифференциальная Диагностика Хронического Сальпингоофорита И Рака Яичников На Основе Иммунологического И Дискриминантного Методов

Агарков Николай Михайлович,К Ф Макконен, В,П В Ткаченко, В А Иванов, А В Иванов,Т. И. Субботина

2017Клиническая лабораторная диагностика

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4[The Diagnostic Significance and Clustering of Parameters of Systemic Humoral Immunity under Acute Endometritis.]

N M Agarkov, V,A V Ivanov,V A Ivanov,D I Kicha,T I Subbotina

The acute endometritis is an actual medical problem in the structure of gynecological pathology and its complications result in incapacitation, infertility and lethality. The purpose of study is to ameliorate laboratory diagnostic of acute endometritis at the expense of selection of diagnostically significant and similar clusters of systemic humoral immunity. he analysis was carried out concerning parameters of systemichumoral immunity in 154 patients with post-natal acute endometritis and 103 patients with non-complicated post-natal period using the radial immunodiffusion technique. The selection of diagnostically significant parameters was implemented at the basis of indices of shifting, disintegration and cluster analysis method. The leading value for laboratory diagnostic of acute endometritis according indices of shifting, disintegration and cluster analysis among parameters of systemic humoral immunity keep content of IgA in blood, absolute number of SD20+ and circulating immune complexes. The selection of diagnostically significant and similar indices of humoral immunity permits to decrease number of detecting parameters at the diagnostic of acute endometritis.

2017Klinicheskaia laboratornaia diagnostika（2017）

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5[The Differentiated Diagnostic of Chronic Salpingoophoritis and Ovary Cancer on the Basis of Immunologic and Discriminant Techniquea.]

N M Agarkov,K F Makkonen, V,P V Tkachenko,V A Ivanov,A V Ivanov,T I Subbotina

The ovary cancer and chronic salpingoophoritis are among leading pathologies of female's sexual sphere and a main cause of morbidity and mortality of female population. The purpose of study was to select leading differential diagnostic indices of systemic cellular immunity and to carry out a differentiation of patients with ovary cancer and chronic salpingoophoritis using discriminant technique. The differentiated diagnostic of ovary cancer and chronic salpingoophoritis was applied to 92 and 87 patients correspondingly to indices of systemic cellular immunity and analyzed by flow cytometry technique. It is demonstrated that the main differential diagnostic indices of systemic cellular immunity in case of ovary cancer and chronic salpingoophoritis are decreasing of relative content of natural killers, absolute number of B-lymphocytes and T-helpers. The developed discriminant models permit to carry out in 91.8%-92.1% cases a faultless differentiated diagnostic of ovary cancer and chronic salpingoophoritis. The approach like that increases quality of differentiated diagnostic of ovary cancer and chronic salpingoophoritis.

2017PubMed引用：1

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