The article presents the results of study of arterial stiffness, ankle-brachial index and pulse pressure in adult population of Tomsk in the framework of the project ESSAY RF (Epidemiology of Cardiovascular diseases in the Regions of the Russian Federation). 1379 men and women of 24-64 y.o. were studied by using volumetric sphygmography (VaSera VS-1500, Fukuda Denshi, Japan).The optimal values of CAVI (cardio-ankle vascular index), as a marker of arterial stiffness, were considered in group of relatively healthy persons in russian population. CAVI values in whole studied population were analyzed in comparison with data of other researchers and in association with CVD and CVD risk factors.

В работе представлен анализ связи уровня фибриногена и Д-димера со степенью тяжести АГ в популяции взрослого неорганизованного населения Томска, выполненный в рамках проекта ЭССЕ-РФ — 2012. Показано, что уже у больных с АГ 1-й степени тяжести уровень фибриногена достоверно выше, чем у лиц с нормальным АД. Среди больных, принимавших гипотензивные препараты, целевые уровни АД были достигнуты только у 38,8%. Уровень фибриногена в этой подгруппе был достоверно ниже, чем у лиц, не достигавших целевого значения АД. По уровню Д-димера достоверно от лиц с нормальным АД отличались только больные с АГ 3-й степени тяжести. Достоверных различий в содержании Д-димера в группах, сформированных в зависимости от достижения целевых значений АД, не выявлено.

Modern data on the prevalence of carotid atherosclerosis (CAS) in the general population are very limited both in Russia and abroad. In this study we investigated the prevalence of CAS using screening ultrasound examination in a random sample of spontaneous population aged 25-64 years in urbanized city of Western Siberia as part of a multicenter observational study ESSE-RF (epidemiology of cardiovascular diseases in different regions of the Russian Federation).The CAS prevalence was 36,4% in males and 24,4% in women in the examined population. We determined large variation of atherosclerotic plaques prevalence, depending on the age and gender. The CAS prevalence in creased more intense in males up to 50 years and in women 50 up to 59 years. Men were twice as likely to had been diagnosed CAS than women. The prevalence of CAS associated with amount of narrowing less than 25 and 50% or more in the examined population was 68,5%, and less than 1%, respectively. According to the results of the study we shouldpay great attention to the processes, leading to intensive development of CAS in the population aged 35-44 years, especially in men. The development of effective approaches to the control of modifiable risk factors for cardiovascular diseases in this age group could be a very appropriate measure for preventing the rapid development of the CAS in the population.

The present article analizes the prevalence of arterial hypertension, features of distribution of the various BP levels, efficiency of its medicamental control in the adult unorganized population of 25–64 years old of the Western Siberian city during one-stage epidemiological research carried out within the framework of the ESSAY Russian Federation-2012 (Epidemiology of Cardio Vascular diseases in regions of the Russian Federation). The unfavorable epidemiological situation was established concerning arterial hypertension in the surveyed population. The received results prove expediency of population strategy of arterial hypertension prevention in the studied group of the population.

Tobacco smoking is one of the modifiable behavioural risk-factors, keeping of which under control correlates with significant improvement of the quality and expectancy of life in population. This review paper aims to highlight the main scientific facts underlying the up-to-date perception of the problem and elaboration of efficient approaches to tobacco control. Issues of prevalence of smoking and impact of different kinds of smoking on cardio-vascular system are presented for discussion.