Based on a combination of modeling and structural analysis methods with immunoinformatic algorithms for digital prediction, structural elements, i.e., subdomains, also called antigenic domains, enriched in B- and T-cell antigenic determinants (epitopes), of the surface ectodomain of glycoprotein B (EctoGB) of human herpes simplex virus type 2 are found and their immunogenicity, allergenicity, and toxicity are predicted. It is established that the proximal β-ribbon domain of EctoGB (subP) adjacent to the viral envelope has the maximum immunogenic potential, which corresponds to the results of an experimental analysis carried out on the EctoGB model of human herpes virus type 5. Further studies of subP will contribute to the development of a new antiherpetic vaccine, and the proposed methodology can be used to search for antigenic domains of viruses of various families.

This review is devoted to analyzing the different aspects of the application of nanobiotechnologies in the health care industry. An assessment of the socio-humanitarian risks that arise in contrast to the invaluable contribution of nanobiotechnologies in improving the health and quality of life of the population is carried out. A principle for the identification and systematization of emerging risks is proposed, taking into account prospects for the development of the transhumanistic strategy of human enhancement using nanotechnologies, which is increasingly popular abroad, together with other convergent technologies. The main factors explaining the lag in the formation of the regulatory framework for applying nanobiotechnologies compared to the pace of scientific and technological development of this area are identified.

Today, a significant part of the world’s population lives in urban agglomerations. A high building density, a large number of vehicles, and industrial enterprises negatively affect both the air quality in the city itself and the climate in general, releasing a significant amount of carbon dioxide. In this regard, there is a need not only to revise the structure of urban developments and strategies for their greening, but also to propose new technologies that radically change the ecological situation. In this paper, solutions using phototrophic microorganisms are considered as such a technology. It is shown that photobioreactors for their cultivation can be successfully integrated into urban systems, while in addition to air purification, the problem of surface wastewater treatment for their further use can also be solved. A wide range of products obtained from the biomass of phototrophic microorganisms significantly increases the economic attractiveness of this approach. Modern technologies in the field of the Internet of Things make it possible to successfully integrate photobioreactors into the urban digital environment.

The processes of producing motor fuels from biomass are considered. The quality of the biofuel is compared. It is suggested that the most promising method for the production of liquid biofuels is a two-stage process that includes hydrothermal carbonization of the biomass followed by hydrogenation of the resulting biochar.