The article deals with the pathogenetic role of desynchronosis in the development of cerebrovascular disease. The results of national and foreign studies of desynchronosis are discussed. It is necessary to proceed with investigation of incidence and structure of desynchronosis in patients with cerebrovascular disease. Chronodiagnosis and chronotherapy of cerebrovascular disease should be introduced into clinical practice
To reduce arm spasticity, 28 patients received injections of botulinum toxin A (Xeomin) in early rehabilitation phase of hemispheric ischemic stroke. The efficacy and safety of treatment was assessed at baseline and 2, 4, 8, 12, 16 weeks after injection. Xeomin significantly reduced muscle tonus in patients with post stroke spasticity of different severity (p