The results of the morphological histochemical analysis of the mirror carp underyearling liver, grown in aquaculture facilities of two different types are described in the article. In series of aquarium experiments on Barbus tetrazona, the fish farming conditions in intensive aquaculture type are simulated, free-radical mechanism of the hepatic cell sublethal and lethal damage by the development of fish liver fatty degeneration is identified.

This paper evaluated the antioxidant effect of prolangirovanny Thiophane as part of an artificial seed feed for carp. The article deals with morphological and functional characteristics and biochemical status of the digestive system of juvenile carp rearing larvae in the transition to exogenous feeding artificial food starting with antioxidant Thiophane in an uncertain hydrochemical regime of nursery ponds. The main etiological factor damaging the tissue cells of various digestive organs authors considered the activation of free radical peroxidation of lipids during hypoxia. Found that after four months after the end of rearing on artificial diet with the introduction of an antioxidant Thiophane content of primary and secondary products of lipid peroxidation was significantly lower and the level of activity of antioxidant enzymes was significantly higher than in fish reared without the technology of antiradical protection.

There has been a comparative quantitative analysis of carotenoids in fish fertilized eggs of Altai mirror carp (Cyprinus carpio), bred by using the traditional technology of aquaculture with the use multi-functional sulfur antioxidant new generation Thiophane. The research resulted in found of antioxidant compounds in the degumming fertilized eggs has a protective effect on the cells of embryos and larvae, reduces the intensity of oxidation processes and provides an efficient use of trophic substances of yolk sac. It has been proved that irrational use of carotenoids in fish eggs under conditions of adaptation to hypoxia through the mechanism of lipid peroxidation affects the formation of bodies and the different physiological systems, as well as of reduction growth and development of embryos and larvae.

The intensity of the free radical lipid peroxidation in the embryos of mirror carp by methods of biochemical and morphological analysis with traditional and new technologies of aquaculture is studied in the article. The effect of oxidative stress on the rate of cleavage and gastrulation in the embryos of fish has been established. The technology of free radical processes control in fish early ontogenesis using a new generation anti-oxidant Thiophane is suggested.