No AccessJournal of UrologyLetter to the Editor/Errata1 Nov 2010Re: A Novel Drug Eluting Ureteral Stent: A Prospective, Randomized, Multicenter Clinical Trial to Evaluate the Safety and Effectiveness of a Ketorolac Loaded Ureteral StentA. E. Krambeck, R. S. Walsh, J. D. Denstedt, G. M. Preminger, J. Li, J. C. Evans and J. E. Lingeman J Urol 2010; 183: 1037–1043 H.B. Joshi, F.X. Keeley, and A.G. Timoney H.B. JoshiH.B. Joshi University Hospital of Wales, Cardiff, United Kingdom More articles by this author , F.X. KeeleyF.X. Keeley Bristol Urological Institute, Bristol, United Kingdom More articles by this author , and A.G. TimoneyA.G. Timoney Bristol Urological Institute, Bristol, United Kingdom More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.06.124AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: A Novel Drug Eluting Ureteral Stent: A Prospective, Randomized, Multicenter Clinical Trial to Evaluate the Safety and Effectiveness of a Ketorolac Loaded Ureteral Stent." The Journal of Urology, 184(5), pp. 2217–2218 References 1 : Ureteral stent symptom questionnaire: development and validation of a multidimensional quality of life measure. J Urol2003; 169: 1060. Link, Google Scholar 2 : Randomized evaluation of ureteral stents using validated symptom questionnaire. J Endourol2005; 19: 990. Google Scholar 3 : Assessing the impact of ureteral stent design on patient comfort. J Urol2009; 181: 2581. Link, Google Scholar © 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 184Issue 5November 2010Page: 2217-2218 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.MetricsAuthor Information H.B. Joshi University Hospital of Wales, Cardiff, United Kingdom More articles by this author F.X. Keeley Bristol Urological Institute, Bristol, United Kingdom More articles by this author A.G. Timoney Bristol Urological Institute, Bristol, United Kingdom More articles by this author Expand All Advertisement Loading ...

To assess the histologic changes in the prostate and the clinical outcome in men with symptomatic benign prostatic hyperplasia (BPH) following transurethral fulguration of the prostate (TUFP) with the roller ball.The study was conducted in two phases. In the first phase of the study, histologic changes in the prostate following fulguration with the roller ball were studied in 10 men with BPH who were already scheduled for transurethral resection of the prostate (TURP). In the second phase of the study, 20 male patients with symptomatic BPH underwent TUFP with the roller ball. All patients had preoperative assessment with history and physical examination, urinalysis, uroflow, transrectal ultrasound of the prostate, serum prostatespecific antigen, serum hemoglobin and electrolytes, and cystoscopy. The procedure was performed under general or spinal anesthesia using standard equipment and 3-mm roller ball. The patients were seen in follow-up at 1, 3, 6, 9, and 12 months.The results of the first phase of the study indicate that the coagulating current results in thermal destruction of prostatic tissue in the form of coagulative necrosis with minimal if any vaporization. The cutting current results in tissue vaporization with minimal coagulative necrosis. Twenty men have enrolled in the second phase of the study. Their mean age is 63.2 ± 7.5 years and their mean follow-up is 4.6 months (range, 1 to 12). Their mean American Urological Association (AUA) symptom score declined from 22.9 ± 4.2 preoperatively to 6.4 ± 4.9, 5.3 ± 3.2, 4.3 ± 1.9, 6 ± 2.9, and 9 at 1, 3, 6, 9, and 12 months, respectively. The mean maximum flow rate (Qmax) increased from 8.9 ± 3.4 mL/s preoperatively to 24.3 ± 1.9 mL/s at 3 months, 22 ± 4.4 mL/s at 6 months, 17.6 + 5 mL/s at 9 months, and 21 mL/s at 12 months postoperatively. The mean prostate volume was 31.9 ± 10 mL and the mean operative time was 44.9 ± 10 minutes. No significant changes were seen in serum hemoglobin and serum sodium. The mean hospital stay was 0.7 day (0 to 2). Nineteen patients had their catheters removed within 24 hours and 1 patient had his catheter removed 48 hours postoperatively. No patient experienced impotence, incontinence, urethral stricture, post-transurethral resection syndrome, or required blood transfusion. In 1 patient (5%) bladder neck stenosis developed at 9 months and 1 patient required TURP for residual apical adenoma at 3 months.The nature and the degree of tissue changes in the prostate following fulguration with the roller ball are well controlled and predictable. When the cutting current is used, prostatic tissue can be removed safely and effectively. The clinical outcome after TUFP with the roller ball demonstrates significant improvement in subjective (AUA symptom score) and objective (Qmax) parameters, with reduced morbidity and short hospital stay. These early results compare favorably with those seen after TURP and laser ablation of the prostate. Larger series with longer follow-up are necessary to establish the long-term efficacy of TUFP in the treatment of BPH.

To compare operative times between retrograde and antegrade ureteric stenting as part of laparoscopic pyeloplasty.

To report and compare the data obtained from the BAUS UK national laparoscopic nephrectomy audit over the past 3 years.

BJU InternationalVolume 97, Issue 5 p. 902-903 Laparoscopic urological surgery: mentor matters ALOYSIUS A. OKEKE, ALOYSIUS A. OKEKE Departments of Urology, Gloucester Royal Hospital, Gloucester, Gloucestershire, Southmead Hospital, andSearch for more papers by this authorANTHONY G. TIMONEY, ANTHONY G. TIMONEY Departments of Urology, Gloucester Royal Hospital, Gloucester, Gloucestershire, Southmead Hospital, andSearch for more papers by this authorMARK P.J. WRIGHT, MARK P.J. WRIGHT Bristol Royal Infirmary, Bristol, Avon, UKSearch for more papers by this author ALOYSIUS A. OKEKE, ALOYSIUS A. OKEKE Departments of Urology, Gloucester Royal Hospital, Gloucester, Gloucestershire, Southmead Hospital, andSearch for more papers by this authorANTHONY G. TIMONEY, ANTHONY G. TIMONEY Departments of Urology, Gloucester Royal Hospital, Gloucester, Gloucestershire, Southmead Hospital, andSearch for more papers by this authorMARK P.J. WRIGHT, MARK P.J. WRIGHT Bristol Royal Infirmary, Bristol, Avon, UKSearch for more papers by this author First published: 06 April 2006 https://doi.org/10.1111/j.1464-410X.2006.06122.x Aloysius A Okeke, Department of Urology, Gloucestershire Hospitals NHS Foundation Trust, Tower 4B, Gloucester Royal Hospital, Great Western Road, Gloucester GL1 3NN, UK. e-mail: Aloysius.Okeke@Glos.nhs.uk Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume97, Issue5May 2006Pages 902-903 RelatedInformation

OBJECTIVETo examine changes in the pathophysiology and frequency of the transurethral resection (TUR) syndrome with two irrigation fluids, as variable amounts of irrigation fluid are absorbed during TUR of the prostate (TURP), and although polar solutes are required to prevent an effect on diathermy, the solutes may have effects when absorbed.PATIENTS AND METHODSBetween December 2001 and March 2003, 250 patients were included in a prospective randomized trial comparing glycine 1.5% with 5% glucose irrigation fluids. We measured blood loss, fluid absorption, temperature change, biochemistry including a glycine assay, and peri‐operative symptoms. Blood samples were taken immediately before and immediately, 5 and 24 h after TURP. Irrigating fluid absorption during TURP was measured with 1% ethanol as a marker and breath ethanol measurements. Operative details were recorded, including the type of anaesthesia (with or with no sedation), resection time and weight of resected tissue. Peri‐operative symptoms were documented prospectively. TUR syndrome was defined as a serum sodium level of ≤ 125 mmol/L with two or more associated symptoms or signs of TUR syndrome.RESULTSFive (2%) patients had TUR syndrome; all five were irrigated with glycine, although this difference was not statistically significant (P = 0.06). Of the five men, three had hypotension, four were tired, one was nauseous, two had parasthesia, two had ‘uneasiness’, one had blurred vision and two were confused; none had chest pain. There was a large variation between the groups in the level of glycine assayed immediately after TURP; a high glycine level was associated with the TUR syndrome (P = 0.01). There was no difference between the groups in levels of sodium, potassium, urea, creatinine, osmolality, calcium, haematocrit, albumin serum levels or peri‐operative blood loss (defined as a change from before to after TURP in haemoglobin level, accounting for transfusions).CONCLUSIONSAn increase in serum glycine was associated with TUR syndrome; there were large variations in the amounts of glycine absorbed, reaching levels many times the upper limit of normal. In other studies, glycine was reportedly toxic, and that the levels recorded were many times the upper limit of normal may have both immediate and long‐term effects.