Objective To analyze the mumps vaccination situation and its influencing factors in medical students in colleges and secondary schools in our city,and to provide some references for the prevention and control of mumps.Methods From September,2016 to June,2018,1 724 college students were selected from three medical colleges in our city by stratified random sampling method,and were surveyed by questionnaire.Results Among the 1 724 medical students,1 002 were vaccinated against mumps,and the vaccination rate was 58.12％.Multivariate logistic regression analysis showed that the students with knowledge score ≥ 7 were more likely to receive mumps vaccination,while the students from technical secondary school and those living in rural areas were less likely to receive mumps vaccination.Conclusion The mumps vaccination rate of medical students in our city is not high.Education background,residence,and knowledge score of mumps are the main factors affecting mumps vaccination of medical students in our city.

目的:探讨综合性健康教育对乙型肝炎患者病情控制及知信行的影响情况.方法:分析收治的120例乙型肝炎患者的临床资料,依据干预方式不同进行分组,对照组(常规性健康教育)60例和观察组(综合性健康教育)60例,观察两组乙型肝炎患者HBV-DNA载量、HBeAg转阴率、HBe Ag血清学转换率情况,观察两组乙型肝炎患者干预前后知信行情况.结果:观察组乙型肝炎患者HBV-DNA载量低于对照组,HBeAg转阴率、HBeAg血清学转换率均高于对照组,观察组乙型肝炎患者疾病认知、健康信念、态度、自我护理能力、生活和饮食习惯、服药依从性均高于对照组,差异有统计学意义(P<0.05).结论:综合性健康教育应用于乙型肝炎患者,可以提高HBeAg转阴率、HBe Ag血清学转换率,利于患者获得良好的知信行,值得临床推广应用.

目的 掌握近年来院内感染发病特点及趋势,为控制感染提供依据.方法 回顾性分析2011-2016年住院病人院内感染监测资料.结果 2011-2016年6年来院内感染例次率为1.13％,院内感染率前3位的科室为ICU(7.62％)、外二科(1.90％)、中医康复科(1.66％);院内感染的部位以下呼吸道为主,占感染例次总数的55.44％.结论 系统了解院内感染特点和趋势后,通过成立三级院感防控网络,采取三网监控和目标性监测,将防控前移至临床一线,能有效降低院内感染发生率,提高医疗质量.

目的:研究并探讨肺功能正常吸烟者高迁移率族蛋白1(high mobility group box-1 protein,HMGB1)和可溶性糖基化终末产物受体(soluble receptor for advanced glycation end product,sRAGE)的表达水平及其临床意义.方法:.选取进行健康体检且肺功能正常的80例健康志愿者作为研究对象,根据体检者是否吸烟将其分为吸烟组40例、非吸烟组40例,收集两组体检者的一般资料,再对其进行肺通气功能检查,并对其血清HMGB1、sRAGE表达水平进行测定.采用皮尔逊相关系数分析法,分析血清HMGB1、sRAGE表达水平与肺功能的相关性.结果:吸烟组与非吸烟组的肺通气功能指标比较,差异无统计学意义(P＞0.05).吸烟组的血清HMGB1表达水平明显高于非吸烟组,其血清sRAGE表达水平明显低于非吸烟组,差异均有统计学意义(P＜0.05).经相关性分析得出,血清HMGB1、sRAGE表达水平与吸烟组的肺通气功能指标密切相关(P＜0.05),HMGB1呈负相关,sRAGE呈正相关;血清HMGB1、sRAGE表达水平与非吸烟组的肺通气功能指标均无线性相关(P＞0.05).结论:肺功能正常的吸烟者其血清HMGB1表达水平异常增高,其血清sRAGE表达水平异常下降,在吸烟者肺功能受损前,可将血清HMGB1、sRAGE作为评估其肺功能的重要指标,以便于及时发现其肺功能受损.