A case of chronic biliary fascioliasis is reported, which was confirmed by endoscopic retrograde cholangiography. After unsuccessful attempts of treatment with classic antiparasitic drugs, cure was obtained with triclabendazole the absorption of which was studied.

Endoscopic electrocoagulation or photocoagulation is now the method of choice for treating colonic angiodysplasia. Follow-up of such patients has not been extensive. The authors report 26 patients with typical and symptomatic lesions who have been treated endoscopically. Follow-up (mean duration, 29.3 months) revealed that 21 patients remained symptom-free after a single procedure. Two patients needed a second procedure before being considered cured. In two others, the need for transfusions was lessened considerably after treatment. The last patient died of terminal cardiac failure. No complications occurred during treatment. Endoscopic treatment is a safe and efficient method for treating bleeding colonic angiodysplasia.

La papillomatose des voies biliaires est une maladie rare, dont une trentaine de cas ont été rapportés dans la littérature. Bien que des formes localisées aient été décrites, l’affection est caractérisée par une tendance à la diffusion au niveau de l’ensemble des voies biliaires, avec un potentiel évolutif malin, qui fait considérer cette maladie par la plupart des auteurs comme une affection prénéoplasique. La symptomatologie, longtemps évolutive dans la majorité des cas, est caractérisée par une obstruction biliaire à répétition, souvent compliquée d’angiocholite consécutive à la croissance tumorale ou à sa sécrétion mucoïde abondante. Le traitement, difficile à codifier, doit être adapté au siège et à l’extension des lésions. La diffusion et le potentiel évolutif malin de la maladie rendent ce traitement très décevant, la plupart du temps limité à des gestes de décompression biliaire palliatifs et souvent itératifs.

The aim of this clinical trial was to compare the frequency of duodenal ulcer healing under omeprazole therapy, giving 30 mg/day or 60 mg/day.

Pour 6tre efficace, la communication scientifique doit respecter des r6gles rigoureuses mais pr6sent6es sans p6dantisme. La devise ~ plus jardinier que bo tan i s te , est rest6e constamment la ligne de mire des auteurs. Ainsi, pour rester pratique, chacun des chapitres commence par l'6nonc6 de r6gles simples, v6dtables d6calogue pour auteurs press6s ou d6butants. Cela n'emp6che pas, h la suite, des d6veloppements intitul6s ~( Pour en savoir un peu p l u s , qui, bien que ramass6s, peuvent satisfaire des curiosit6s suppl6mentaires.

Il est possible que dans un avenir très proche, le diagnostic de colite pseudomembraneuse secondaire aux antibiotiques soit bactériologique.

Les auteurs rapportent deux cas d'adénocarcinome œsophagien développé sur un épithélium de Barrett avec hernie hiatale. Ils discutent le résultat de la confrontation entre les données de l'endoscopie, des biopsies étagées multiples, et de l'examen de la pièce opératoire. Cette analyse conduit à adopter une attitude prospective en présence d'un endobrachyœsophage ou de lésions de métaplasie gastrique au niveau de l'œsophage.

This report on the macroscopic data yielded by fibergastroscopy and multiple sight controlled biopsies, in a series of 10 cases of gastric lymphomas, emphasizes the diagnostic value of the morphological characteristics observed on the lesion which, in all cases, had multiple localisations. In spite of repeated sample collection, the number of correct histological diagnoses is less than in gastric adenocarcinomas. Even if the authors' multiple gastric biopsies provide nearly as many accurate diagnoses as reached by other authors with the exfoliative cytology technique, this should not deter them from associating the two diagnostic methods.

Abstract. In the dog, as shown before in the human, the major plasma proteins in hepatic bile (albumin, orosomucoid, transferrin and immunoglobulin IgG), with the exception of immunoglobulin IgA, were found to be derived entirely from the plasma. Biliary IgA was shown to have two sources, the plasma and local biosynthesis. These conclusions were based on comparisons on specific radioactivities of different proteins in plasma and bile, after intravenous injection of canine plasma whose proteins had been labelled biosynthetically with tritium. — The transfer of plasma proteins from blood to bile was found to proceed along two parallel pathways, one involving bulk transfer of unmodified plasma, and one based on molecular sieving favouring the transfer of plasma proteins of low molecular weight. — From a comparative study of hepatic lymph and plasma, it was concluded that the molecular sieve process was completed by the time the plasma proteins reached the interstitial fluid. The sieving membrane was therefore assigned anatomically to the vascular walls, which were found to have the properties of an isoporous membrane with a pore radius of 102 Å. No further molecular sieving was found to take place during the crossing of the second barrier between blood and bile, viz. the epithelial sheet separating interstitial fluid from the bile.