Journal of Pediatric Gastroenterology and NutritionVolume 39, Issue S1 p. S502-S502 ABSTRACTS: Poster Session Abstracts P1171 DO DIGESTIVE AND NUTRITIONAL TROUBLES CONSTITUTE PROBLEM FOR PAEDIATRICIAN ? RESULTS OF A SURVEY. L. D. Van Egroo, L. D. Van Egroo Medical Department, Nestle, NoisielSearch for more papers by this authorF. Huet, F. Huet Pediatric Department, CHU, DijonSearch for more papers by this authorC. Van Egroo, C. Van Egroo Medical Department, Clin Eval et Com, Clin Eval et Com, FranceSearch for more papers by this authorE. Lachambre, E. Lachambre Medical Department, Nestle, NoisielSearch for more papers by this author L. D. Van Egroo, L. D. Van Egroo Medical Department, Nestle, NoisielSearch for more papers by this authorF. Huet, F. Huet Pediatric Department, CHU, DijonSearch for more papers by this authorC. Van Egroo, C. Van Egroo Medical Department, Clin Eval et Com, Clin Eval et Com, FranceSearch for more papers by this authorE. Lachambre, E. Lachambre Medical Department, Nestle, NoisielSearch for more papers by this author First published: 01 June 2004 https://doi.org/10.1002/j.1536-4801.2004.tb13601.x Submitted by: [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume39, IssueS1June 2004Pages S502-S502 RelatedInformation
Journal of Pediatric Gastroenterology and NutritionVolume 39, Issue S1 p. S472-S472 ABSTRACTS: Poster Session Abstracts P1094 NEW BORN’S MANAGEMENT AFTER LEAVING MATERNITY: A FRENCH PAEDIATRICIAN POLL L. Van Egroo, L. Van Egroo Medical department, Nestlé France, Marne la vallée, CAENSearch for more papers by this authorG. De Schrevel, G. De Schrevel Paediatric department, CHU, CAENSearch for more papers by this authorC. Van Egroo, C. Van Egroo Medical department, Clin Eval et Com, Chaville, FranceSearch for more papers by this author L. Van Egroo, L. Van Egroo Medical department, Nestlé France, Marne la vallée, CAENSearch for more papers by this authorG. De Schrevel, G. De Schrevel Paediatric department, CHU, CAENSearch for more papers by this authorC. Van Egroo, C. Van Egroo Medical department, Clin Eval et Com, Chaville, FranceSearch for more papers by this author First published: 01 June 2004 https://doi.org/10.1002/j.1536-4801.2004.tb13524.x Submitted by: Louis-Dominique. [email protected] Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume39, IssueS1June 2004Pages S472-S472 RelatedInformation
Bilateral visual field constriction has been recently reported in patients treated with vigabatrin. It has been considered that vigabatrin, a GABA agonist antiepileptic drug, was specifically responsible for this visual field defect. We present four observations sharing the same characteristics of chronic tunnel vision. Three patients had had vigabatrin but the fourth one received other antiepileptic drugs, progabide, an agonist of post-synaptic GABA receptors, and phenobarbital which interferes with GABA-A receptors. It is thus possible to hypothesize a retinal toxicity triggered by chronically increased GABA transmission. If this is confirmed, an accurate incidence of symptomatic and asymptomatic visual field constriction with GABA-mimetic drugs should be established, as well as the patients' profiles which are more at risk. Patients currently under this type of treatment should be checked by both manual and automatic perimetry every six months to one year.
Bilateral visual field constriction has been recently reported in patients treated with vigabatrin. It has been considered that vigabatrin, a GABA agonist antiepileptic drug, was specifically responsible for this visual field defect. We present four observations sharing the same characteristics of chronic tunnel vision. Three patients had had vigabatrin but the fourth one received other antiepileptic drugs, progabide, an agonist of post-synaptic GABA receptors, and phenobarbital which interferes with GABA-A receptors. It is thus possible to hypothesize a retinal toxicity triggered by chronically increased GABA transmission. If this is confirmed, an accurate incidence of symptomatic and asymptomatic visual field constriction with GABA-mimetic drugs should be established, as well as the patients' profiles which are more at risk. Patients currently under this type of treatment should be checked by both manual and automatic perimetry every six months to one year.
