肌肉退变是人口老龄化过程的主要特征之一，是老龄化社会的一个常见问题。2010年，欧洲肌少症工作组（EWGSOP）首先发表了肌少症共识，定义肌少症为一种增龄相关的肌肉量减少、肌肉力量下降和（或）躯体功能减退的老年综合征 [1] 。长久以来，脊柱椎旁肌肉维持脊柱稳定性的作用一直得到认可。腰椎椎旁肌肉如多裂肌和竖脊肌的特征与多种脊柱疾病的病理过程相匹配，如下腰痛、腰椎间盘突出症、腰椎活脱及脊柱畸形等 [2-5] 。

分化型甲状腺癌占甲状腺癌的90％,10年生存率可达98％,骨转移可达2％-13％[1],发生骨转移后10年生存率下降至14％-21％.隐匿型甲状腺癌(OCT)是分化型甲状腺癌的一个亚型.由于其无特殊症状且体积小,易发生漏诊,多见于尸检或其他原因导致的甲状腺切除而做的病理检查[2].本文报道1例收治的多发骨转移无原发灶的隐匿型甲状腺癌患者.

目的研究苏木乙醇提取物(SME)对坐骨神经损伤小鼠免疫功能的影响。方法选取成年雄性Balb/c小鼠60只,随机分为SME高中低剂量组和空白对照组,行右侧坐骨神经离断吻合术,分别于术后3、5、7、14、28d以MTT法测定淋巴细胞增殖转化能力,ELISA法测定血清循环免疫复合物(CIC)浓度。结果各时间点小鼠淋巴细胞增殖转化能力及血清CIC浓度与SME剂量呈明确的量效关系。结论SME能够影响坐骨神经损伤小鼠的细胞及体液免疫功能,且与用药剂量存在明确量效关系。

Objective To explore the effect of Caesalpinia sappan ethanol extract on the myelin basic protein in blood serum and the nerve function in mouse after sciatic nerve injury.Methods Adult male Balb/c mouse were randomly divided into the normal control-group and the experimental-group with high middle or low dose of Caesalpinia sappan ethanol extract,the right sciatic nerve was transected and inosculated.The mouse survived for 3,5days and 1,2,4,8,12weeks after operation.The MBP was detected by ELISA and the nerve function was detected by electromyography.Results The concentration of MBP in blood serum and the resules of electromyography had dose-effect relationship with SME.Conclusion Caesalpinia sappan ethanol extract could effect the regeneration of nerve in mouse after sciatic nerve injury,there is dose-effect relationship between SME and the effection.

放射性臂丛神经损伤是乳腺癌根治术后的常见并发症,放疗后到出现症状的潜伏期可短至数月, 长可达20年.放射治疗的同时应用化学治疗使臂丛神经损伤的发生率更高[1].本文拟探讨神经肌电图对乳癌根治术后臂丛神经损伤的诊断意义及单纯化学治疗能否作为乳癌根治术后臂丛神经损伤的原因之一.