Pericardial effusion (PE) is a common clinical condition that can develop as a result of systemic or cardiac diseases. Here, we report the results of cytology for patients who underwent pericardiocentesis for PE.

Background Pericardial effusion (PE) is a common clinical condition that can develop as a result of systemic or cardiac diseases. Here, we report the results of cytology for patients who underwent pericardiocentesis for PE. Methods The study comprised 283 patients who underwent primary percutaneous pericardiocentesis between 2007 and 2016. The mean age of the patients was 60.0 ± 16.6 years; 162 (57.2%) were male and 121 (42.8%) were female. The presence of reactive mesothelial cells, acute and chronic inflammatory cells, and/or blood without evidence of malignant cells was considered as benign. The presence of malignant cells with/without reactive mesothelial cells, inflammatory cells, and/or blood was considered as malignant. Results The vast majority of PE specimens (219 cases; 77.4%) were classified as benign. Only 20 cases (7.1%) were classified as atypical, and malignant cells were present in the PE specimens of 44 cases (15.5%). The most common diagnosis was benign PE. The most commonly encountered malignancy was lung cancer. The rate of malignancy was 1.9% in the serous group and 24% in the hemorrhagic group, which was statistically significant. Conclusion Benign PE was the most frequent cytological diagnosis in our study. Chronic nonspecific pericarditis was the most frequent type of pericarditis in the benign PE group, while lung adenocarcinoma was the most frequent malignancy in the malignant PE group. The rate of malignancy was significantly higher in the hemorrhagic group than in the serous group.

Ça­lış­ma­ pla­nı:­ Merkezimizde Mart 2011 Mart 2014 tarihleri arasında 822 hastadan (500 erkek, 322 kadın; ort. yaş 56±13 yıl; dağılım 16-83 yıl) edinilen 1700 endobronşiyal ultrasonografi eşliğinde transbronşiyal ince iğne aspirasyonu örneği retrospektif olarak analiz edildi. Tüm sitolojik materyaller ve işlem notları (lenf nodu veya lezyon boyutu, yerleşim yeri, iğne girişimi sayısı ve yayma preparat sayısı) gibi örnek yeterliliği ile ilişkili olabilecek değişkenler incelendi.