OBJECTIVE: This study’s objective was to compare the effectiveness of the delirium prediction model (pre-deliric) and the early prediction model (E-pre-deliric) in delirium prediction in an intensive care unit (ICU) according to the Intensive Care Delirium Screening Checklist (ICDSC). Our aim was to determine these models’ usability and cut-off values for ICU patients. PATIENTS AND METHODS: We classified the studied patients based on their highest ICDSC scores (tested twice daily) during ICU hospitalization. ICDSC scores of 4 or higher indicated positive results for delirium, whereas a score of 0 represented a negative result. We recorded the patients’ demographic and clinical details and characteristics and calculated their E-pre-deliric and pre-deliric version 1 and version 2 scores. To evaluate the effectiveness of the models, we used receiver operating characteristic (ROC) curve analysis. RESULTS: Two hundred fifty patients (55.6% males, mean age 60.6±18.7 years) participated in this study. Their mean Acute Physiology and Chronic Health Evaluation II (APACHE-II) score was 17.0±9.1. Delirium was more common in men, patients of older ages, those with high APACHE-II scores, those who had undergone urgent admissions, those with histories of trauma, those with high urea or creatinine values and those who had undergone sedation or mechanical ventilation. Compared to patients who did not develop delirium, those who did had longer ICU stays and hospital stays, as well as greater mortality risk. The cutoff values for the patients’ pre-deliric version 1, pre-deliric version 2 and E-pre-deliric scores were 38% [area under ROC (AUROC)=1], 22% (AUROC=1) and 28% (AUROC=1), respectively. CONCLUSIONS: This study is the first to compare the pre-deliric and E-pre-deliric prediction models. These models’ validity and reliability were acceptable. They were clinically useful, and we identified their cut-off values. These models provide options for early detection of delirium and are easily applicable in the ICU.
Objective: Technological advances increased prolonged life expectancy of the terminal patients, who had end-stage diseases. End-of-life care in intensive care units (ICU) has increased with the rise in admissions of terminal patients to ICU. Our aims in this study were to determine the prevalence of terminal patients, and to find the reasons for potentially inappropriate treatments in ICUs. Materials and Methods: It was nationwide, multicenter, point prevalence and observational study. All adult patients, who stayed more than 48 h in the ICU, were enrolled. All patients were recorded on an electronic case record form, consisting of data on patient demographics, treatments, family participation and mini survey for physicians. The study was conducted on October 15, 2018 with a follow-up for 30 days. Results: Of 1127 patients 286 (25%) ICU patients were diagnosed as terminal patients by ICU physicians depending on primary physician statement. Terminal patients relatives requests and physicians legal concerns reduced end-of-life care quality. Terminal patients had significantly increased usage of mechanical ventilation, inotropic drugs, and poor end-of-life care quality (p<0.001). Fifty-four percent of the terminal patients didn’t have any end-of-life decisions at discharge. Half of the terminal patient relatives requested the full code. Without legal concerns, most of the physicians would apply do not resuscitate (86%), withhold (77%) and withdraw (53%) to terminal patients at the end-of-life. Conclusion: Terminal patients occupy an important place in the ICU. To increase the quality of terminal patients’ end-of-life care in the ICU, advanced care planning and legal arrangements should be conducted properly.
OBJECTIVE:Prone positioning has been found to improve oxygenation in most patients with acute respiratory distress syndrome (ARDS). The study aimed to investigate the effectiveness of the prone position in patients with ARDS. PATIENTS AND METHODS:The prone position is one of the ventilator techniques included in recent guidelines for acute respiratory distress syndrome. This study was a retrospective evaluation of the records of 100 ARDS patients who were administered prone position mechanical ventilation in our intensive care unit. All patients were placed in the prone position for a total of 12 hours per day at 4-hour intervals (supine-prone) while admitted to the intensive care unit. RESULTS:This study included 100 participants. These patients were divided into two groups as survivors [(n=38, 16 females, 22 males, median age: 60 (24-86)] and non-survivors [(n=62, 19 females, 43 males, median age: 64 (21-93)], according to their intensive care follow-ups. Acute physiology and chronic health evaluation (APACHE) II score, the sequential organ failure assessment score (SOFA), and inflammation markers were statistically significantly higher in the non-survivor group. Between the two groups, there was no statistically significant difference in terms of fundamental characteristics. In the sub-group evaluation of the subjects in patients with ARDS with and without novel coronavirus disease 2019 (COVID-19) groups, the patients in the COVID-19 (+) group were older, had shorter hospital stays, had higher APACHE II and SOFA scores, and higher rates of cardiovascular disease and sepsis. CONCLUSIONS:Applying prone-position mechanical ventilation in the cohorts of our patients with ARDS resulted in a demonstrable significant improvement in the oxygenation levels of our patients.
The apnea test is used for the diagnosis of brain death. Various complications have been reported to have developed during the apnea test. A 44-year-old woman was hospitalized in the intensive care unit due to unconsciousness due to a posterior inferior carotid artery aneurysm. On the forty-ninth day of her hospitalization in the intensive care unit, the patient had no motor response and all brain stem reflexes were negative. Brain death was considered in the patient, but subcutaneous emphysema and bilateral pneumothorax developed within minutes during the apnea test. The patient underwent bilateral tube thoracostomy. The patient could not be diagnosed with brain death and died on the fiftieth day of her hospitalization. This report emphasizes that multiple complications can be observed during the apnea test and underlying mechanisms and therapeutic approaches are discussed.
Increased intraabdominal pressure (IAP) has deleterious effects on intracranial pressure. In this study, we intended to investigate the effects of intraabdominal pressure values on intracranial pressure (ICP) measured by ultrasound-assisted optic nerve sheath diameter (ONSD) measurement in patients who underwent major surgery. Observational study. All patients’ age, gender, weight, types of surgeries, comorbidities, Acute Physiology and Chronic Health Evaluation (APACHE) score, Sequential Organ Failure Assessment (SOFA) score, operation time, and amount of fluid administered during the operation were all recorded. Intraabdominal pressure and optic nerve sheath diameter measurements were measured. The patients were separated into 3 groups: group I, intraabdominal pressure 0–11 mmHg; group II, intraabdominal pressure 12–19 mmHg; and group III, intraabdominal pressure 20 mmHg and above. Intensive care unit (ICU) stay and prognosis were all recorded. Intraabdominal pressure, left optic nerve sheath diameter, right optic nerve sheath diameter, and heart rate (HR) measurements were meaningfully higher in group II and group III compared to group I ( p < 0.001 for each), and group III was significantly higher compared to group I ( p < 0.001). In patients with high intraabdominal pressure, optic nerve sheath diameter follow-up with ultrasonography gains great importance. We recommend that attention should be paid to this situation.
Mucormycosis; is a rapidly progressive fungal infection due to filamentous fungi of the mucoraceae family. In this case report, we aimed to present the diagnosis and treatment modalities of a patient who developed rhinoorbital mucormycosis. A 54-year-old patient with a history of hypertension applied to the emergency department with a complaint of wound in the mouth that started four days ago. In the examinations performed here, the patient was diagnosed with diabetic ketoacidosis. In the examination of the patient, it was found that there was a necrotic wound on the left hard palate, a necrotic wound extending from the left inferior turbinate to the nasopharynx, and hyphae in the nasal passage. The patient underwent an aggressive debridement operation on the third day, due to the growth in the fungal culture. In the following clinical examination of the patient, ketone in the urine became negative, and his acidosis status improved. On the same day, the patient was treated with a positive coronavirus disease-2019 (COVID-19) polymerase chain reaction. After 15 days of treatment, the patient died due to COVID-19 pneumonia. Mucormycosis should be doubtful in patients presenting with uncontrolled diabetes mellitus and severe sino-orbital infection. All physicians following diabetic ketoacidosis should be vigilant against this rapidly progressing disease with high mortality.
Background and aims: Malnutrition is frequently detected in septic patients and is important cause of mortality. Methods: Numerical rating Scale 2002, Nutrition risk in the critically ill score and adductor pollicis thickness measurement are used to determine malnutrition in 287 septic patients. Results: The mean age was 66,57 +/- 16,31 years. The mean APACHE II score was 16,19 +/- 8,20 while the mean SOFA score was 5,89 +/- 3,49. To NRS 2002 test 171 was accepted as high malnutrition risk while 116 patients was accepted as low malnutrition risk. According to Nutric test, the risk of malnutrition was found to be low in 144 patients and found to be high in 143 patients. The mean APTM was detected as 20,20 +/- 2,21 mm. The cuff-off point for APTM was found as <= 21 mm. Conclusions: high risk of malnutrition was frequently observed in patients with sepsis and mortality was higher in high risk patients. Higher sensitivity was achieved when the tests were combined with each other. As a result, we recommend the use of malnutrition screening tests in patients with sepsis and combining the tests with each other.
Delirium is an organic dysfunction including the brain's inflammatory response to injury, hormonal effects and changes in neurotransmission and neural network. Delirium is one of the major causes of weaning difficulty in intensive care unit (ICU) patients. In this case report, we tried to explain the successful weaning procedure in a patient using quetiapine after trying all treatment options due to delirium in the ICU. This report emphasizes that second-generation antipsychotics should be kept in mind in patients who cannot be disconnected from the mechanical ventilator due to delirium.
Tracheal ruptures are one of the life-threatening situations in critical care unit and can be formed after trauma, intubation, tracheotomy, bronchoscopy or spontaneously. Significant risk factors for tracheal rupture include urgent intubation, use of stilet, high cuff pressure, recurrent intubation attempts, double lumen endotracheal tubes, very thick endotracheal tubes, female gender, short height, older age, tracheomalacia, tracheal stenosis, congenital tracheal abnormalities and chronic steroid therapy. Among these risk factors, corticosteroids can cause rupture by inhibiting collagen synthesis and reducing connective tissue stability. In this case report, a case with spontaneous recurrent tracheal rupture was defined and the underlying mechanisms and therapeutic approach to this complication that could be seen in patients using chronic steroids were discussed.
Objective: As a result of advanced mechanical ventilation and hemodynamic support applications, the duration of intensive care stay is prolonged.Investigation of effective causes of prolonged ICU stay is important in terms of effective use of intensive care units.Materials and Methods: Patients who were hospitalized for more than 24 hours in the ICU during one year were included into the study.Age, gender, Body Mass index, hospitalization, location (emergency, operating room, service), presence of operation, presence of emergency / elective operation, need for vasopressor, Glaskow coma score (GCS), Full Outline of Unresponsiveness score (FOUR), Acute Physiology and Chronic Health Evaluation score, simplified acute physiology (SAPS III) score, hemogram profile, biochemical profile and coagulation profile values were recorded.All patients were classified as stay in the intensive care unit for shorter than 14 days and 14 days and more.We tried to investigate factors affecting prolonged admission by comparing these values.Results: Advanced age, high urea value, low GCS, low FOUR score, high SAPS III value, need for MV and need for vasoactive agent were found to be effective factors in prolonged intensive care hospitalization. Conclusion:We think that extensive studies should be done in this area as more effective use of intensive care units may be possible as a result of trying to reveal the factors affecting prolonged intensive care.
Objective: As a result of advanced mechanical ventilation and hemodynamic support applications, the duration of intensive care stay is prolonged.Investigation of effective causes of prolonged ICU stay is important in terms of effective use of intensive care units.Materials and Methods: Patients who were hospitalized for more than 24 hours in the ICU during one year were included into the study.Age, gender, Body Mass index, hospitalization, location (emergency, operating room, service), presence of operation, presence of emergency / elective operation, need for vasopressor, Glaskow coma score (GCS), Full Outline of Unresponsiveness score (FOUR), Acute Physiology and Chronic Health Evaluation score, simplified acute physiology (SAPS III) score, hemogram profile, biochemical profile and coagulation profile values were recorded.All patients were classified as stay in the intensive care unit for shorter than 14 days and 14 days and more.We tried to investigate factors affecting prolonged admission by comparing these values.Results: Advanced age, high urea value, low GCS, low FOUR score, high SAPS III value, need for MV and need for vasoactive agent were found to be effective factors in prolonged intensive care hospitalization. Conclusion:We think that extensive studies should be done in this area as more effective use of intensive care units may be possible as a result of trying to reveal the factors affecting prolonged intensive care.
Takotsubo cardiomyopathy (TC) is a disease mimicking Acute Coronary syndrome with electrocardiographic changes as well as temporary, reversible regional wall motion defect in the apical and middle segments of the left ventricle. It may be associated with emotional and physical stress caused by serious medical discomfort or surgical stress. Although it is more common in postmenopausal women, it is thought that stress-induced catecholamine discharge causes TC. Intensive care patients are at high risk for emotional and physical stress due to various factors such as multisystem diseases and problems due to prolonged hospitalization. In this case report, we aimed to present the characteristics of TC following long-term intensive care follow-up of our patient who was paraplegic due to cervical trauma and conscious, and to discuss the differential diagnosis and evaluate the literature.
A pneumoperitoneum during laparoscopic procedures has deleterious effects on cerebral perfusion and oxygenation. Our aim was to assess the effects of different insufflation pressures on cerebral oxygen saturation (rSO2) using a noninvasive INVOS Cerebral Oximeter (Somanetics Corporation, USA) system. One hundred patients scheduled for laparoscopic cholecystectomy were included and divided into two groups: a 10 mmHg pneumoperitoneum group (group I) and a 14 mmHg pneumoperitoneum group (group II). The rSO2 measurements were obtained preinsufflation, after insufflation, every 15 min after insufflation, and 10 min after desufflation. Hemodynamic variables and anesthesia and surgery times were recorded. Between the two groups, there were no statistically significant differences in terms of age, sex, weight, anesthesia times, or surgery times (p > 0.05). The hemodynamic variables were similar in the two groups (p > 0.05). The rSO2 value changed over time, with a statistically significant between-group difference (p = 0.001). The preinsufflation rSO2 value was 70.07 ± 7.73 in group I and 72.21 ± 6.58 in group II, with no significant between-group difference (p > 0.05). After insufflation, the rSO2 value decreased to 69.60 ± 7.74 in group I and 64.41 ± 6.48 in group II, and the distinction was statistically significant (p < 0.001). A high-pressure pneumoperitoneum was associated with a greater decrease in rSO2 as compared to a low-pressure pneumoperitoneum. Thus, we suggest the use of a low-pressure pneumoperitoneum in patients with central nervous system pathologies.
Posterior reversible encephalopathy (PRES) syndrome is a clinical-radiological condition characterized by headache, changes in consciousness, epilepsy and visual disturbances, and usually occurs in the posterior parietal and occipital regions with vasogenic edema due to different etiologic factors. Risk factors include preeclampsia/eclampsia as well as hypertension, human immunodeficiency virus infection, organ transplantation, immunosuppressive and cytotoxic therapy, and analgesics. Treatment is usually aimed at correcting the cause of PRES. The aim of this case report was to present the characteristics of PRES, which was secondary to eclampsia in two cases, to discuss the differential diagnosis and to review the literature.
Objective: Elevated intraabdominal pressure (IAP) is an important factor that increases morbidity and mortality in intensive care unit patients. In this study, it was aimed to investigate the risk factors related to IAP increase in intensive care unit patients. Materials and Methods: One hundred twenty five patients who stayed more than 24 hours in surgical and reanimation intensive care unit were included into the study. All patiens age, sex, body mass index, APACHE II and SOFA scores were recorded. IAP measurements were performed during the intensive care unit stay, intraabdominal hypertension (IAH) was approved by a sustained or repeated pathological elevation in IAP >= 12 mmHg. Abdominal compartment syndrome (ACS) was accepted as a sustained IAP >20 mmHg that is associated with new organ dysfunction. All patients' duration of mechanical ventilator, intensive care unit stay and prognosis were determined. Risk factors for IAP such as trauma, sepsis, multiple blood transfusions, ileus, acidosis and pneumonia were all recorded. Result: In the study 45 patients were diagnosed with IAP and 5 patients with ACS. There was no difference in terms of IAH and ACS according to gender and age of the patients. Patients with high body mass index, multiple transfusions, sepsis and pneumonia, were found to have higher IAH (p<0.05) and no difference was found in terms of ACS. There was no significant difference in terms of IAH and ACS in patients with trauma. IAH and ACS were found significantly higher in patients with ileus (p<0.05). Significant difference was determined in terms of ACS for acidosis in patients who participate to the study (p<0.05). Patients who had IAH had higher APACHE II and SOFA scores, longer intensive care and mechanical ventilation (p<0.05). Conclusion: High body mass index, sepsis, multiple transfusion, ileus, acidosis and pneumonia are important risk factors for development of IAH and ACS, we recommend that patients should be monitored more carefully in the presence of these risk factors.
Objective: Delirium is frequently seen in intensive care patients and causes prolongation of mechanical ventilation and intensive care stay. In intensive care patients, the pre-delirium score is a test used to detect delirium. We aimed to determine the prognostic value of the pre-delirium score in patients who stayed more than 24 hours in our intensive care unit. Materials and Methods: Between January 1, 2016 and December 31, 2016, pre-delirium scores were calculated for all patients stayed more than 24 hours in surgery, reanimation and internal medicine intensive care units. Pre-delirium score >= 50 was accepted as group 1 and <50 was accepted as group 2. The groups were compared with each other in terms of gender, age, Acute Physiology and Chronic Health Evaluation (APACHE II) scores, duration of hospitalization and mortality rates. Results: While a high pre-delirium score was determined in 196 patients (39.2%), a low pre-delirium score was determined in 304 cases (60.8%) (group 2). In group 1, the mean age was 68.47 +/- 15.83 years and the mean APACHE II score was 22.47 +/- 7.75; in group 2 the mean age was 59.18 +/- 18.48 years and the mean APACHE II score was 15.71 +/- 7.87, which was found significantly higher than group 1 (p<0.05). In group 1, the duration of hospitalization was 19.93 +/- 23.46 days and the mortality rate was 65.3%; in group 2, the duration of hospitalization was 13.02 +/- 20.01 days and the mortality rate was 40.5%. Significant difference determined in terms of duration of hospitalization and mortality (p<0.05). Conclusion: Early recognition and treatment of delirium will lead to significant improvements in the prognosis of intensive care unit patients. We think that the predelirium score can also be used as an important prognostic test in intensive care unit patients.
Background: Pregnancy-induced anatomical and physiological changes in the airway make airway management difficult in obstetric patients; thus, preoperative evaluation of the airway is important for obstetric patients. Aims: To determine the effectiveness of the modified Mallampati test; the interincisor, sternomental and thyromental distances and the upper limb bite test. The second aim was to assess the effectiveness of the combination of the upper limb bite test with the other tests in obstetric patients. Study Design: Cross-sectional study. Methods: Pregnant women (n=250) scheduled for caesarean section were analysed. The patients’ ages, heights and weights were collected. Preoperative airway evaluation was done by using a modified version of the Mallampati test. The interincisor, sternomental and thyromental distances were measured, and the upper limb bite test was performed. The laryngoscopy difficulty was evaluated by using Cormack-Lehane classification. Results: No statistically significant differences were found between groups in age, height or weight (p>0.05). The modified Mallampati test and interincisor, sternomental and thyromental distances revealed a lower number of easy intubations than that determined by the Cormack-Lehane classification and a higher number of difficult intubations than the actual number of cases (p<0.05). The sensitivity and specificity of the modified Mallampati test, the upper limb bite test, the interincisor distance test and the sternomental and thyromental distance tests were found to be 73.08, 57.69, 84.62, 80.77 and 88.46 and 90.62, 99.11, 83.04, 84.37 and 87.05, respectively. When the combinations were examined, the sensitivity and specificity of the combination of the upper limb bite test with the modified Mallampati test were found to be 57.69 and 100, respectively. When the upper limb bite test was combined with the interincisor distance, the sensitivity and specificity were 46.15 and 100, respectively. We found a sensitivity and specificity of 93.75 and 95.30, respectively, for the combination of the upper limb bite test with the thyromental distance test. The sensitivity and specificity of the combination of the upper limb bite test with the modified Mallampati test and interincisor distance test were found to be 46.15 and 100, respectively. For combination of all the tests, the sensitivity and specificity was 42.31 and 100, respectively. Conclusion: When all combinations are evaluated in the decision of difficult intubation, the combination of the upper limb bite test and thyromental distance test is superior to the use of other methods alone to predict difficult intubation in pregnant women.
Apesar dos novos avanços em reanimação cardiopulmonar (RCP), o dano cerebral muitas vezes ocorre após a reanimação. Avaliar o valor prognóstico de medir a saturação de oxigênio cerebral (rSO2) para estimar o prognóstico em pacientes após a reanimação cardiopulmonar. Análise retrospectiva. Foram avaliados após RCP 25 pacientes (12 do sexo feminino e 13 do masculino). Todos os pacientes foram submetidos à hipotermia (temperatura alvo de 33‐34 °C). As mensurações da Escala de Coma de Glascow (GCS), dos reflexos corneanos (RC), dos reflexos pupilares (RP) e do excesso de base (EB) e rSO2 foram feitas na admissão. Na hipertermia, as mensurações de GCS, RC, RP, EB e rSO2 foram feitas depois que a temperatura atingiu 36 °C. Em sobreviventes, o valor basal de rSO2 foi de 67,5 (46‐70) e a diferença percentual entre o valor basal e a hipertermia de rSO2 foi de 0,03 (0,014‐0,435). Em não sobreviventes, o valor basal de rSO2 foi de 30 (25‐65) e a diferença percentual entre o valor basal de hipotermia de rSO2 foi de 0,031 (‐0,08‐20). Não houve diferença estatística nas variações percentuais entre os valores da rSO2 na fase basal e de reaquecimento. Uma diferença estatisticamente significativa foi observada entre os valores da GCS na fase basal e de reaquecimento dos grupos (p = 0,004). Não houve diferença estatisticamente significativa entre GCS, RC, RP, EB e rSO2 para determinar o prognóstico. Embora os valores da rSO2 tenham sido mais elevados em sobreviventes do que em não sobreviventes, não observamos uma diferença estatisticamente significativa dos valores da rSO2 entre os grupos na fase basal e de reaquecimento. Como a mensuração é simples, e não afetada por hipotensão e hipotermia, a rSO2 pode ser um indicador útil para determinar o prognóstico após a RCP. Despite new improvements on cardiopulmonary resuscitation (CPR), brain damage is very often after resuscitation. To assess the prognostic value of cerebral oxygen saturation measurement (rSO2) for assessing prognosis on patients after cardiopulmonary resuscitation. Retrospective analysis. We analyzed 25 post‐CPR patients (12 female and 13 male). All the patients were cooled to a target temperature of 33–34 °C. The Glascow Coma Scale (GCS), Corneal Reflexes (CR), Pupillary Reflexes (PR), arterial Base Excess (BE) and rSO2 measurements were taken on admission. The rewarming GCS, CR, PR, BE and rSO2 measurements were made after the patient's temperature reached 36 °C. In survivors, the baseline rSO2 value was 67.5 (46–70) and the percent difference between baseline and rewarming rSO2 value was 0.03 (0.014–0.435). In non‐survivors, the baseline rSO2 value was 30 (25–65) and the percent difference between baseline and rewarming rSO2 value was 0.031 (−0.08 to −20). No statistical difference was detected on percent changes between baseline and rewarming values of rSO2. Statistically significant difference was detected between baseline and rewarming GCS groups (p = 0.004). No statistical difference was detected between GCS, CR, PR, BE and rSO2 to determine the prognosis. Despite higher values of rSO2 on survivors than non‐survivors, we found no statistically considerable difference between groups on baseline and the rewarming rSO2 values. Since the measurement is simple, and not affected by hypotension and hypothermia, the rSO2 may be a useful predictor for determining the prognosis after CPR.
Introduction. Dynamic tests for predicting fluid responsiveness have generated increased interest in recent years. One of these tests, pulse pressure variation (PPV), is a parameter calculated from respiratory variations of pulse pressure. Another test, pleth variability index (PVI), is based on respiratory variations of the perfusion index and can be measured non-invasively by pulse oximeter. Previous studies have shown that both tests are valuable in determining fluid responsiveness. Methods. In this observational prospective study, our aim was to compare the PVI and PPV in order to identify a convenient tool for determining fluid responsiveness. Our study was performed in a surgical and reanimation intensive care unit. We enrolled one hundred mechanically ventilated adult patients diagnosed with sepsis. Exclusion criteria included brain death, spontaneous breathing, cardiac arrhythmia, and impaired peripheral circulation. We measured the PPV by arterial monitorization and the PVI by using Masimo Radical 7 in the 45 degrees semi-recumbent position (SP) and then 15 degrees Trendelenbug position (TP). We performed correlation and ROC analysis using a >13% fluid responsiveness cut-off value for the PPV and >14% for the PVI. Results. Between the SP and the TP, we did not observe significant decreases in PPV (from 14.17 +/- 10.57 to 12.66 +/- 9.64; p > 0.05), while we did observe significant decreases in PVI (from 21.91 +/- 13.99 to 20.46 +/- 14.12; p < 0.05). The PPV fluid responsiveness cut-off value in the SP and TP was 20% (78.95% sensitivity, 77.05% specificity) and 18% (76.67% sensitivity, 72.46% specificity), respectively. The PVI fluid responsiveness cut-off value in the SP and TP was 20% (80.49% sensitivity, 81.03% specificity) and 16% (81.25% sensitivity, 62.69% specificity), respectively. The area under the ROC of the PPV and PVI was 0.843 and 0.858 in the SP, respectively, and 0.760 and 0.747 in the TP, respectively. The PPV and PVI were correlated in the SP (r = 0.578; p = 0.001) and the TP (r = 0.517; p = 0.001). Conclusions. Our results showed that the PPV and PVI were correlated independent of position change in sepsis patients. Both tests appear to be equivalently reliable. However, the ability of the PPV and PVI to predict fluid responsiveness decreased in the TP in our study.