The Authors report a case of Wilkie's syndrome recently observed. This unusual observation is suitable for some clinical and therapeutic considerations. X-ray examination and abdominal CT played a decisive role for the diagnosis. Among the large number of operations till now proposed for the management of this syndrome, the Authors preferred the latero-terminal duodeno-jejunum anastomosis. Such intervention, in fact, is easy and quick and allows to preserve a physiological intestinal function.