The treatment of lover limb erysipelas rests on antibiotic therapy directed against streptococci, but the necessity of prescribing a concomitant anticoagulant treatment has not yet been established. The incidence of deep vein thrombosis in patients with erysipelas of the leg in unknown. In a prospective study of 40 patients presenting with this type of skin disease, we looked for deep vein thrombosis, using systematically pulsed Doppler vein exploration combined with ultrasonography and, if necessary, a second Doppler examination and a phlebography. Six cases of deep vein thrombosis were diagnosed. This complication was observed in 5 patients at high risk for deep venous thrombosis; it had never been foreseen at clinical examination.

Les auteurs rapportent un cas de sclérodermie systémique associée à un adénocarcinome bronchopulmonaire primitif: cette association a déjà été rapportée au cours de sclérodermies anciennes compliquées de fibrose pulmonaire importante, cette dernière ayant un rôle supposé de lésion précancéreuse. L'observation rapportée est particulière par l'absence de fibrose pulmonaire.

Focal dermal hypoplasia is a rare genetic disorder characterized by diffuse and specific cutaneous lesions. Multiple visceral abnormalities are frequently associated. A minimal form of the disease (only cutaneous and localized to one thigh) is reported in the father of a woman who had typical focal dermal hypoplasia.

The authors report a case of systemic sclerosis associated with primary lung adenocarcinoma. This association has previously been reported in patients with old scleroderma complicated by extensive fibrosis of the lungs allegedly regarded as a precancerous lesion. The case reported here is of interest owing to the absence of pulmonary fibrosis.

The authors report a case of systemic sclerosis associated with primary lung adenocarcinoma. This association has previously been reported in patients with old scleroderma complicated by extensive fibrosis of the lungs allegedly regarded as a precancerous lesion. The case reported here is of interest owing to the absence of pulmonary fibrosis.

Kaposi's sarcoma frequently develops in patients with immune deficiency which may be drug-induced (corticosteroids, immunodepressants). We report a case of Kaposi's sarcoma in a 75-year old man who had been taking oral prednisone continually for 7 years as treatment of severe asthma. Data from the literature clearly show that corticosteroid therapy may trigger the development of Kaposi's sarcoma in patients who usually possess several other pathogenetic factors of that disease, such as pre-existing immune deficiency, environmental (viruses) or genetic factors. In some cases, withdrawing corticosteroids may result in complete remission of the cutaneous lesions.

Le développement d'un sarcome de Kaposi est sourvent associé à un état d'immunodéficience qui peut être iatrogène, dû à un traitement corticoïde et/ou immunosuppresseur. L'observation que nous rapportons est celle d'un patient de 75 ans, traité par prednisone de façon ininterrompue depuis 7 ans pour un asthme sévère. Les données de la littérature montrent bien le rôle de la corticothérapie comme facteur déclenchant d'un sarcome de Kaposi chez des patients possédant habituellement plusieurs autres facteurs pathogéniques de la maladie: déficit immunitaire préexistant, facteurs environmentaux (virus), facteurs génétiques. L'arrêt de la corticothérapie peut conduire parfois à une régression complète des lésions cutanées.

Congenital mesoblastic nephroma is a benign neoplasm of the kidney which is usually diagnosed during the first three months of life. We report herein a case of mesoblastic nephroma in a 69 year-old man. At this age, diagnosis can only be made by histopathologic examination of the operative specimen. This was the case for our patient and the five other cases reported in the literature. Histogenesis of mesoblastic nephroma is open to debate: mesenchymal origin for some authors, tumor of the blastema for most of the others.

A 65 year old woman had a minimal changes nephrotic syndrome (MCNS) with steroid-induced remission. An underlying malignancy was discovered at the time of relapse of proteinuria: it was a retroperitoneal chordoid sarcoma. Even though the tumor could not be excised, complete remission was again observed with corticosteroids. There was no second relapse when prednisone was discontinued and during the seven months before the patient died. This is a new unusual case of MCNS associated with carcinoma. The response of nephrotic syndrome steroid therapy is further suggestive evidence that deficiency in T-cell function may be involved.