Journal of Food ScienceVolume 28, Issue 1 p. 64-64 Pectin Content of Raisins M. ALICE BROWN, M. ALICE BROWN Western Regional Research Laboratory Agricultural Research Service, U.S. Department of Agriculture, Albany, CaliforniaSearch for more papers by this authorJAMES R. WOODWARD, JAMES R. WOODWARD Western Regional Research Laboratory Agricultural Research Service, U.S. Department of Agriculture, Albany, CaliforniaSearch for more papers by this authorFLOYD DeEDS, FLOYD DeEDS Western Regional Research Laboratory Agricultural Research Service, U.S. Department of Agriculture, Albany, CaliforniaSearch for more papers by this author M. ALICE BROWN, M. ALICE BROWN Western Regional Research Laboratory Agricultural Research Service, U.S. Department of Agriculture, Albany, CaliforniaSearch for more papers by this authorJAMES R. WOODWARD, JAMES R. WOODWARD Western Regional Research Laboratory Agricultural Research Service, U.S. Department of Agriculture, Albany, CaliforniaSearch for more papers by this authorFLOYD DeEDS, FLOYD DeEDS Western Regional Research Laboratory Agricultural Research Service, U.S. Department of Agriculture, Albany, CaliforniaSearch for more papers by this author First published: January 1963 https://doi.org/10.1111/j.1365-2621.1963.tb00160.xCitations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES Kertesz, Z. I., 1951. “ The Pectic Substances.” p. 302. Interscience Publishers, New York . McComb, E. A., and R. M. McCready, 1952. Calorimetric determination of pectic substances. Anal. Chem 24, 1630. McCready, R. M., and E. A. McComb, 1952. Extraction and determination of total pectic materials in fruits. Anal. Chem 24, 1986. Citing Literature Volume28, Issue1January 1963Pages 64-64 ReferencesRelatedInformation

The phenomenon of passive cutaneous anaphylaxis in guinea pigs was shown to be applicable in the laboratory determination of residual antigenicity in fractionated and chemically treated castor-seed proteins. Six protein fractions obtained by paper-strip electrophoresis of castorseed protein were shown to be antigenic.

Rats fed a low-methionine, low-choline diet containing 1% of gallic acid developed fatty livers. Added choline or methionine prevented the increased liver fat. Pyrogallol, in contrast, did not cause fatty livers. These results are in agreement with the metabolism studies in that gallic acid, but not pyrogallol, is O-methylated in the animal body.

Rats ingesting diets containing 0.5% biphenyl developed nephrotoxic effects including focal tubular dilation in approximately 60 days. Rats returned to control diet for 60 days after ingesting a dietary level of 0.5% biphenyl for 165 days showed a regression of kidney lesions with scar formation. A more sensitive criterion of the renal effects of biphenyl was polyuria, which is probably a defense mechanism response to the irritant action caused by the insoluble biphenyl metabolites passing through the kidney. No evidence of either polyuria or histopathologic damage was observed from the ingestion of 0.1% biphenyl in the diet for 120 days.

The castor seed antigen CB-1A, prepared by the basic lead acetate method of Spieset al., has been subjected to column chromatography on diethylaminoethyl cellulose. Antigenic differences between fractions were found by the, Schultz-Dale technique, which indicated the possible existence of six antigenic or allergenic components.

A water-soluble, heat-stable protein component of castor seed meal was subjected to paper-strip electrophoresis in buffers of different chemical composition, pH values, and ionic strengths. It was shown that phosphate buffer at pH 7.4 to 8.0 and an ionic strength of approximately 0.05 gave a sharp resolution of castor seed proteins into bands which would bind bromophenol blue. Spies' Allergen CB-1A was shown to be resolved into six or more components at pH 8.0. Each major component band was found to be antigenic by passive cutaneous anaphylaxis in guinea pigs that were sensitized with rabbit antiserum to the crude castor seed protein preparation. Five bands were shown to be allergenic to humans.

Journal of Food ScienceVolume 25, Issue 3 p. 328-336 A TOXICOLOGICAL STUDY OF BIPHENYL, A CITRUS FUNGISTAT ANTHONY M. AMBROSE, ANTHONY M. AMBROSE Western Regional Research Laboratory, b Albany, California U. S. Army Environmental Health Laboratory of the Army Medical Service, Army Chemical Center, Md.Search for more papers by this authorALBERT N. BOOTH, ALBERT N. BOOTH Western Regional Research Laboratory, b Albany, CaliforniaSearch for more papers by this authorFLOYD DEEDS, FLOYD DEEDS Western Regional Research Laboratory, b Albany, CaliforniaSearch for more papers by this authorALVIN J. COX JR., ALVIN J. COX JR. Department of Pathology, Stanford University School of Medicine, San Francisco, Calif.Search for more papers by this author ANTHONY M. AMBROSE, ANTHONY M. AMBROSE Western Regional Research Laboratory, b Albany, California U. S. Army Environmental Health Laboratory of the Army Medical Service, Army Chemical Center, Md.Search for more papers by this authorALBERT N. BOOTH, ALBERT N. BOOTH Western Regional Research Laboratory, b Albany, CaliforniaSearch for more papers by this authorFLOYD DEEDS, FLOYD DEEDS Western Regional Research Laboratory, b Albany, CaliforniaSearch for more papers by this authorALVIN J. COX JR., ALVIN J. COX JR. Department of Pathology, Stanford University School of Medicine, San Francisco, Calif.Search for more papers by this author First published: May 1960 https://doi.org/10.1111/j.1365-2621.1960.tb00338.xCitations: 44 A laboratory of the Western Utilization Research and Development Division, Agric. Research Service, U.S. Department of Agriculture. The results of this investigation are summarized and commented upon with the kind permission of the Stanford Research Institute and the Crown Zellerbach Corporation. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume25, Issue3May 1960Pages 328-336 RelatedInformation

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFeedstuffs Antioxidants, Toxicity Studies on the Antioxidant 6-Ethoxy-1,2-dihydro-2,2,4-trimethylquinolineR. H. Wilson and Floyd DeEdsCite this: J. Agric. Food Chem. 1959, 7, 3, 203–206Publication Date (Print):March 1, 1959Publication History Published online1 May 2002Published inissue 1 March 1959https://pubs.acs.org/doi/10.1021/jf60097a008https://doi.org/10.1021/jf60097a008research-articleACS PublicationsRequest reuse permissionsArticle Views52Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Journal of Food ScienceVolume 23, Issue 5 p. 550-553 EFFECT OF ACETOSTEARIN ON REPRODUCTION IN ALBINO RATS ANTHONY M. AMBROSE, ANTHONY M. AMBROSE Western Regional Research and Development Division Agricultural Research Service U. S. Department of Agriculture Albany 10, California U. S. Army Environmental Health Laboratory of the Army Medical Service, Army Chemical Center, Maryland.Search for more papers by this authorDOROTHY J. ROBBINS, DOROTHY J. ROBBINS Western Regional Research and Development Division Agricultural Research Service U. S. Department of Agriculture Albany 10, CaliforniaSearch for more papers by this authorFLOYD DeEDS, FLOYD DeEDS Western Regional Research and Development Division Agricultural Research Service U. S. Department of Agriculture Albany 10, CaliforniaSearch for more papers by this author ANTHONY M. AMBROSE, ANTHONY M. AMBROSE Western Regional Research and Development Division Agricultural Research Service U. S. Department of Agriculture Albany 10, California U. S. Army Environmental Health Laboratory of the Army Medical Service, Army Chemical Center, Maryland.Search for more papers by this authorDOROTHY J. ROBBINS, DOROTHY J. ROBBINS Western Regional Research and Development Division Agricultural Research Service U. S. Department of Agriculture Albany 10, CaliforniaSearch for more papers by this authorFLOYD DeEDS, FLOYD DeEDS Western Regional Research and Development Division Agricultural Research Service U. S. Department of Agriculture Albany 10, CaliforniaSearch for more papers by this author First published: September 1958 https://doi.org/10.1111/j.1365-2621.1958.tb17602.xCitations: 2 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume23, Issue5September 1958Pages 550-553 RelatedInformation

Dihydroquercetin, which is closely related to quercetin in chemical structure, has been shown to be nontoxic when fed to albino rats at a dietary level of 1 per cent for long periods of time. Chromatographic examination of the urine of two human volunteers before and after the ingestion of 2 grams of dihydroquercetin demonstrated the conversion of the compound to 3,4-dihydroxyphenyl-acetic, m-hydroxyphenylacetic, and 3-methoxy-4-hydroxyphenylacetic acids. These same metabolites are excreted following oral administration of quercetin, or DOPA, to rats, rabbits, or humans.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntioxidant Toxicity, Toxicological Studies on SesamolA. M. Ambrose, A. J. Cox Jr., and Floyd DeEdsCite this: J. Agric. Food Chem. 1958, 6, 8, 600–604Publication Date (Print):August 1, 1958Publication History Published online1 May 2002Published inissue 1 August 1958https://pubs.acs.org/doi/10.1021/jf60090a008https://doi.org/10.1021/jf60090a008research-articleACS PublicationsRequest reuse permissionsArticle Views181Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Dihydroquercetin, which is closely related to quercetin in chemical structure, has been shown to be nontoxic when fed to albino rats at a dietary level of 1 per cent for long periods of time. Chromatographic examination of the urine of two human volunteers before and after the ingestion of 2 grams of dihydroquercetin demonstrated the conversion of the compound to 3,4-dihydroxyphenyl-acetic, m -hydroxyphenylacetic, and 3-methoxy-4-hydroxyphenylacetic acids. These same metabolites are excreted following oral administration of quercetin, or DOPA, to rats, rabbits, or humans.

Journal of Food ScienceVolume 20, Issue 6 p. 582-586 CHRONIC TOXICITY STUDY OF PHYTIC-ACID-TREATED SOYBEAN OIL FOR RATS ALBERT N. BOOTH, ALBERT N. BOOTH U. S. Department of Agriculture, Agricultural Research Service Western Utilization Research Branch, Albany 10, CaliforniaSearch for more papers by this authorFLOYD DeEDS, FLOYD DeEDS U. S. Department of Agriculture, Agricultural Research Service Western Utilization Research Branch, Albany 10, CaliforniaSearch for more papers by this author ALBERT N. BOOTH, ALBERT N. BOOTH U. S. Department of Agriculture, Agricultural Research Service Western Utilization Research Branch, Albany 10, CaliforniaSearch for more papers by this authorFLOYD DeEDS, FLOYD DeEDS U. S. Department of Agriculture, Agricultural Research Service Western Utilization Research Branch, Albany 10, CaliforniaSearch for more papers by this author First published: November 1955 https://doi.org/10.1111/j.1365-2621.1955.tb16872.xCitations: 1AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume20, Issue6November 1955Pages 582-586 RelatedInformation

Data are given on the continued oral ingestion of dried cells of Bacillus megaterium and brewers' yeast by rats for four hundred days. No toxic effects were observed in rats ingesting diets containing up to 20 per cent of B. megaterium or brewers' yeast as judged by growth response, hemoglobin values, organ weights, and histopathological examination of the visceral organs.

The metabolic fate of orally administered rutin or its aglycone, quercetin, has been investigated in rabbits. Evidence for the absorption and metabolism of these compounds is based upon the urinary excretion of degradation products. One of these products has been isolated and identified as 3,4‐dihydroxyphenylacetic acid. The amount isolated accounts for at least 2 5 per cent of the quercetin administered.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT3,4-DIHYDROXYPHENYLACETIC ACID—A METABOLITE OF QUERCETINCharles W. Murray, Albert N. Booth, Floyd DeEds, and Robert H. WilsonCite this: J. Am. Chem. Soc. 1953, 75, 13, 3289Publication Date (Print):July 1, 1953Publication History Published online1 May 2002Published inissue 1 July 1953https://pubs.acs.org/doi/10.1021/ja01109a521https://doi.org/10.1021/ja01109a521research-articleACS PublicationsRequest reuse permissionsArticle Views93Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Data are given on the toxicity of quercetin and quercitrin after intravenous administration in rabbits and rats after oral ingestion of diets containing as much as 1 per cent of quercetin or quercitrin for approximately 410 days. The results indicate a low order of toxicity as judged by growth, amount of food consumed, hematological findings, organ weights, and microscopical examination of stained section of visceral organs.

Summary and ConclusionsLong‐term feeding experiments with albino rats involving concentrations of lauryl gallate as high as 0.5% in the daily diet produced no deleterious effects as judged by food intake, rate of growth, gross observations at time of autopsy, and histopathological examination of tissues. Diets containing 1.0% lauryl gallate definitely inhibited growth of male rats and retarded growth of females slightly. Levels of 2.5 and 5% lauryl gallate caused no histopathological changes in various organs but decreased the food intake to a point where starvation was an obvious factor in death of the animals. Lauryl gallate produced skin irritation but did not produce skin sensitization. The property of skin irritation might be of importance to workers engaged in the production and handling of lauryl gallate. There is no evidence to indicate that ingestion of slight amounts, such as might be encountered in edible fats and oils protected against oxidation, would produce harmful effects.