Screw fixation remains the primary clinical strategy for osteoporotic fractures (OPF). However, impaired osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) and limited cellular migration often lead by osseointegration failure and screw loosening. Inspired by the architectural concept of "column-interface synergistic load-bearing", we developed a polydopamine-functionalized coaxial electrospun nanofiber scaffold (S-MS-PDA) to address both biological and mechanical fixation challenges at the screw-bone interface. The scaffold's coaxial design enabled the spatiotemporal sequential release of bioactive factors, including SDF-1 and P24, precisely modulating MAPK, JAK-STAT, Wnt, and bone remodeling pathways. This approach promoted BMSCs recruitment and osteogenic differentiation, rapidly establishing an early osteogenic microenvironment. Additionally, polydopamine-mediated interface engineering created a biomimetic transition zone, improving mechanical compatibility between the screw and bone and modulating local inflammation. In a rat osteoporosis model, the S-MS-PDA scaffold significantly reduced interfacial stress concentration and enhanced the boneimplant contact by 3.31 fold. This study presents a novel scaffold system that integrates biological activation with mechanical reinforcement, offering a promising tissue engineering strategy for the internal fixation of osteoporotic fractures.

Hemophilic arthropathy (HA), a major complication of hemophilia, is a chronic osteoarthropathy driven by repeated joint bleeding. Although traditional therapies such as coagulation factor replacement, physical rehabilitation, and surgery can manage symptoms, they cannot fundamentally repair established joint damage or break the pathological cascades. This review systematically summarizes therapeutic frontiers in HA, including regenerative medicine, molecular targeting, and gene therapy. Regenerative medicine aims to restore joint function through tissue repair using mesenchymal stem cells and their exosomes, as well as multifunctional biomaterials such as nanocarriers and hydrogels for targeted delivery and microenvironment modulation. Molecular targeting offers precision treatment by interfering with key pathological pathways using monoclonal antibodies that either improve coagulation or target pro-inflammatory factors. Non-coding RNAs are also being explored for their roles in regulating inflammation and cartilage degradation. Gene therapy, a paradigm shift from symptomatic care to fundamental repair, enables continuous endogenous production of coagulation factors, thereby preventing bleeding and delaying HA progression. The successful translation of these therapies into clinical practice requires overcoming challenges such as optimizing cell survival in hostile environments, standardizing biomaterial production, managing immune responses to vectors, and reducing costs. Future research should focus on interdisciplinary strategies, personalized treatment plans, and long-term follow-up studies to achieve synergistic effects and ensure safety. These innovative approaches promise to significantly improve joint function and quality of life for HA patients, ultimately working toward a functional cure.

This study aims to evaluate the effectiveness of skin staplers for wound closure following extended L-shaped incisions in the treatment of calcaneal fractures. A randomized controlled trial was performed on 82 calcaneal fracture cases (Sanders types III-IV) that underwent extended L-shaped incisions at the Second Hospital of Shanxi Medical University from June 2022 to March 2025. Out of these, 60 cases met the inclusion and exclusion criteria. A non-blinded, open, randomized controlled trial was conducted, assigning patients to either the stapler group (n = 28) or the Allgower-Donati group (n = 32). The key parameters assessed included wound closure time, the area of postoperative inflammatory reaction, changes in skin temperature at the incision corners, and wound healing grades. These parameters were then compared between the two groups. At the 2-week postoperative follow-up, when sutures were removed, no significant differences were found in terms of inflammatory reaction area, skin temperature changes, or wound healing grades between the two groups. However, the stapler group demonstrated a notably shorter wound closure time (10.89 ± 2.87 min) compared to the Allgower-Donati group (20.44 ± 2.01 min). The use of skin staplers for wound closure resulted in healing outcomes that showed no statistically significant differences from those achieved with the Allgower-Donati suturing technique in extended L-shaped incisions for calcaneal fractures. Importantly, the skin stapler method significantly reduces wound closure time (P < 0.05), which can lead to shorter overall surgical durations and a decreased risk of wound infections.

Rüedi–Allgöwer Ⅲ Pilon fractures represent extremely complex injuries with notable therapeutic challenges. Herein, we propose a novel, reliable, and reproducible method: the four-step fixed-base reconstruction method, performed via an internal plating-assisted single-incision anterolateral approach. A retrospective study was conducted on 168 cases with Rüedi–Allgöwer type III Pilon fractures treated using either the four-step base-fixed reconstruction method utilizing internal plating-assisted single-incision anterolateral approach (four-step reconstruction group) or the traditional double-plate fixation method (traditional group). Preoperative and postoperative length of stay, operation time, frequency of intraoperative fluoroscopy, intraoperative blood loss, fracture healing time, complication rates, and postoperative outcomes at two years, including the American Orthopaedic Foot and Ankle Society (AOFAS) ankle–hindfoot score, visual analog scale (VAS) pain score, Mazur ankle score, and range of motion (ROM) during ankle dorsiflexion and plantarflexion, were thoroughly documented and compared. Compared with the traditional group, the four-step reconstruction group exhibited significantly shorter postoperative length of stay and operation time (P < 0.05), fewer intraoperative fluoroscopies, less intraoperative blood loss, and lower complication rates (P < 0.05). Additionally, the four-step reconstruction group demonstrated significantly higher AOFAS and Mazur scores (P < 0.05) and greater ankle dorsiflexion (P < 0.05). No significant differences were found between the groups regarding preoperative hospital stays, fracture healing times, VAS scores, or ankle plantarflexion angles. The four-step fixed-base reconstruction method utilizing internal plating-assisted single-incision anterolateral approach is one of the recommended options for the management of Rüedi–Allgöwer Ⅲ Pilon fractures.

Successful bone fragment fixation is a crucial factor in bone fracture healing, the fixation of crushed bone fragments could hinder bone fracture healing. Thus, ideal bone glues to effectively adhere and splice comminuted bone fragments are needed in clinical. Herein, an osteoinductive and biodegradable double cross-linked bone glue (GelMA-oDex-AMBGN) was constructed through Schiff's base reaction between commercial GelMA (with different substitution degrees of amino groups) and Odex mixed with amine-modified mesoporous bioactive glass nanoparticles (AMBGN), followed by crosslink with blue light irradiation. The GelMA-oDex-AMBGN bone glue successfully adhered and spliced the comminuted bone fragments of isolated rat skulls. GelMA-oDex-AMBGN promoted the proliferation of 3T3 cells and enhanced the expression of osteogenic proteins Runx2 and OCN in vitro. In rat cranial critical-sized defect models, GelMA-oDex-AMBGNs with different substitution degrees significantly increased the new bone contents at the fracture defect sites and promoted bone tissue regeneration in vivo. In conclusion, the double cross-linked bone glue (GelMA-oDex-AMBGN) was successfully constructed and can induce bone regeneration. Additionally, there was no significant difference in osteogenic activity among GelMA-oDex-AMBGNs with different substitution degrees and the equal content of AMBGN.

Abstract Objective To assess the clinical efficacy of anti-target and target injections on osteoporotic vertebral compression fracture (OVCF). Method A total of 104 OVCF cases, treated via target or anti-target injections, between Jun 2015 and Mar 2022, in the Second Hospital of Shanxi Medical University (the same team), were retrospectively analyzed. The gender, age, bone density, operation time, and percutaneous vertebroplasty (PVP )injection volume of all cases were carefully recorded, and the percutaneous vertebroplasty (PVP) permeability was compared. Next, we investigated the VAS scores before the operation, as well as 24 h, 3 months, and at the last follow-up after the operation, and compared the vertebral compression relief (anterior vertebral compression relief, central vertebral compression relief, and kyphosis correction degree), based on the acquired X-ray data. Results In the anti-target injection group, the average age was 68.77 ± 5.96 years old, the PVP injection volume was 4.646 ± 0.404 mL, and the operation time was 40.55 ± 5.615 min. We observed no significant difference in the VAS score between the target and anti-target injection groups at 24 h, 3 months, and at the last follow-up after the operation. However, the kyphosis correction degree, as well as the anterior and central vertebral compressions relief of the anti-target and target injection groups exhibited statistically significant differences. In particular, the injected PVP permeability was significantly lower in the anti-target injection group (1.8%), compared to the target injection group (22%) (P = 0.001). Conclusions Both anti-target and target injection groups demonstrated consistent OVCF clinical efficacy. However, the anti-target injection group had drastically reduced PVP permeability and enhanced safety.

Abstract Objective To assess the clinical efficacy of anti-target and target injections on osteoporotic vertebral compression fracture (OVCF). Method A total of 104 OVCF cases, treated via target or anti-target injections, between Jun 2015 and Mar 2022, in the Second Hospital of Shanxi Medical University (the same team), were retrospectively analyzed. The gender, age, bone density, operation time, and percutaneous vertebroplasty (PVP )injection volume of all cases were carefully recorded, and the percutaneous vertebroplasty (PVP) permeability was compared. Next, we investigated the VAS scores before the operation, as well as 24 h, 3 months, and at the last follow-up after the operation, and compared the vertebral compression relief (anterior vertebral compression relief, central vertebral compression relief, and kyphosis correction degree), based on the acquired X-ray data. Results In the anti-target injection group, the average age was 68.77 ± 5.96 years old, the PVP injection volume was 4.646 ± 0.404 mL, and the operation time was 40.55 ± 5.615 min. We observed no significant difference in the VAS score between the target and anti-target injection groups at 24 h, 3 months, and at the last follow-up after the operation. However, the kyphosis correction degree, as well as the anterior and central vertebral compressions relief of the anti-target and target injection groups exhibited statistically significant differences. In particular, the injected PVP permeability was significantly lower in the anti-target injection group (1.8%), compared to the target injection group (22%) (P = 0.001). Conclusions Both anti-target and target injection groups demonstrated consistent OVCF clinical efficacy. However, the anti-target injection group had drastically reduced PVP permeability and enhanced safety.

The effective osteointegration of orthopedic implants is a key factor for the success of orthopedic surgery. However, local metabolic imbalance around implants under osteoporosis condition could jeopardize the fixation effect. Inspired by the bone structure and the composition around implants under osteoporosis condition, alendronate (A) was grafted onto methacryloyl hyaluronic acid (H) by activating the carboxyl group of methacryloyl hyaluronic acid to be bonded to inorganic calcium phosphate on trabecular bone, which is then integrated with aminated bioactive glass (AB) modified by oxidized dextran (O) for further adhesion to organic collagen on the trabecular bone. The hybrid hydrogel could be solidified on cancellous bone in situ under UV irradiation and exhibits dual adhesion to organic collagen and inorganic apatite, promoting osteointegration of orthopedic implants, resulting in firm stabilization of the implants in cancellous bone areas. In vitro, the hydrogel was evidenced to promote osteogenic differentiation of embryonic mouse osteoblast precursor cells (MC3T3-E1) as well as inhibit the receptor activator of nuclear factor-κ B ligand (RANKL)-induced osteoclast differentiation of macrophages, leading to the upregulation of osteogenic-related gene and protein expression. In a rat osteoporosis model, the bone-implant contact (BIC) of the hybrid hydrogel group increased by 2.77, which is directly linked to improved mechanical stability of the orthopedic implants. Overall, this organic-inorganic, dual-adhesive hydrogel could be a promising candidate for enhancing the stability of orthopedic implants under osteoporotic conditions.

The effective fixation of fracture fragments is the foundation for the smooth healing process of fracture. Due to the presence of small fracture fragments, the comminuted fracture cannot be fixed under high mechanical strength leading to the bone nonunion and delayed healing. In this study, the primary crosslinked injectable bone glue was fabricated by the Schiff base reaction between low substitution degree methacrylate gelatin (GelMa) and Oxidized dextran (oDex) covalently crosslinked with Aminated mesoporous bioactive glass nanoparticles (AMBGN), then the second crosslinked bone glue was formed among small fracture fragments after the irradiation. By this method, the osteogenic dual-crosslinking biodegradable bone glue was synthesized with enhanced mechanical capability. This bone glue was biocompatible and biodegradable, in addition, after the second crosslinking, the mechanical strength was 2.1 times higher than that in primary cross-linking. Moreover, the dual-crosslinked bone glue also exhibited excellent adhesion ability on the isolated rat bone tissues. Additionally, the bone glue can increase the proliferation of bone marrow mesenchymal stem cells (BMSCs) and enhance the expression of Alkaline phosphatase (ALP) and the deposition of calcium nodules with the up-regulating expression of the osteogenic protein (Runx2) and adhesin (Vinculin) in vitro. Furthermore, the bone glue also presented enhanced osteogenesis in the rat calvarial critical-size defect models in vivo. Overall, this osteogenic dual-crosslinking biodegradable bone glue with high mechanical strength provided a new approach in treating the comminuted fracture fragments.

Background In complex injuries, external fixation device represents a challenge to maintain negative-pressure wound therapy (NPWT). In this trial, we compared a combination of bone wax and colostomy paste versus bone wax alone to seal NPWT around external fixation devices. Methods Debridement surgeries of limbs with open fracture and large soft tissue defect need NPWT to be applied around the external fixation devices were randomized into two groups. The seal between external fixation devices and the drape was established using either bone wax first and then reinforced with colostomy paste or bone wax alone. The primary outcome was seal failure within 3 days of debridement. Secondary outcomes included the number of seal failure per debridement surgery and the time spent in repairing the seal within 3 days. Results A total of 56 debridement surgeries were enrolled: 28 to the bone wax/colostomy paste group versus 28 to the bone wax control group. One patient in the control group died 1 day after the first debridement surgery. One patient in the bone wax/colostomy paste group was transferred to other hospitals within 3 days. The final analysis included 27 debridement surgeries in the bone wax/colostomy paste group and 27 debridement surgeries in the control group. The rate of seal failure (defined by loss of negative pressure at anytime within 3 days) was 81.5% (22/27) in the control group versus 11.1% (3/27) in the bone wax/colostomy paste group ( p < 0.001; χ 2 test). The bone wax/colostomy paste group also had significantly lower number of seal failures per debridement (median of 0 vs. 2; p = 0.004), and shorter time spent in repairing the seal (median of 0 vs. 18 min; p < 0.001). Conclusions Using bone wax followed by colostomy paste to seal NPWT around external fixation devices reduces seal failure.

Intervertebral disc degeneration (IDD) is related to the deterioration of nucleus pulposus (NP) cells due to hypertrophic differentiation and calcification. The imbalance of pro-inflammatory (M1 type) and anti-inflammatory (M2 type) macrophages contributes to maintaining tissue integrity. Here, we aimed to probe the effect of Magnoflorine (MAG) on NP cell apoptosis mediated by “M1” polarized macrophages. THP-1 cells were treated with lipopolysaccharide (LPS) to induce “M1” polarized macrophages. Under the treatment with increasing concentrations of MAG, the expression of pro-inflammatory cytokines (IL-1β, IL-6, TNF-α, IL-18), high mobility group box protein 1 (HMGB1), as well as myeloid differentiation factor 88 (MyD88), nuclear factor kappa B (NF-κB) and NOD-like receptor 3 (NLRP3) inflammasomes in THP-1 cells were determined. What’s more, human NP cells were treated with the conditioned medium (CM) from THP-1 cells. The NP cell viability and apoptosis were evaluated. Western blot (WB) was adopted to monitor the expression of apoptosis-related proteins (Bax, Caspase3, and Caspase9), catabolic enzymes (MMP-3, MMP-13, ADAMTS-4, and ADAMTS-5), and extracellular matrix (ECM) compositions (collagen II and aggrecan) in NP cells. As a result, LPS evidently promoted the expression of pro-inflammatory cytokines and HMGB1, the MyD88-NF-κB activation, and the NLRP3 inflammasome profile in THP-1 cells, while MAG obviously inhibited the "M1″ polarization of THP-1 cells. After treatment with “M1” polarized THP-1 cell CM, NP cell viability was decreased, while cell apoptosis, the pro-inflammatory cytokines, apoptosis-related proteins, and catabolic enzymes were distinctly up-regulated, and ECM compositions were reduced. After treatment with MAG, NP cell damages were dramatically eased. Furthermore, MAG dampened the HMGB1 expression and inactivated the MyD88/NF-κB pathway and NLRP3 inflammasome in NP cells. In conclusion, this study confirmed that MAG alleviates “M1” polarized macrophage-mediated NP cell damage by inactivating the HMGB1-MyD88-NF-κB pathway and NLRP3 inflammasome, which provides a new reference for IDD treatment.

Background: Complications in treating comminuted tibial plateau fractures with extensive soft tissue damage are common. In this study, we discussed the effect of staged treatment in the reconstruction of the lateral column with autogenous iliac bone using case follow-up. Methods: A retrospective analysis of 18 patients with comminuted tibial plateau fractures and extensive soft tissue damage from October 2016 to February 2020 who underwent staged treatment in our hospital. After the soft tissue damage repair, a large autologous iliac bone was used to reconstruct the lateral column of the tibial plateau. Results: All 18 patients were followed up over the course of 8-40 months, with an average of 23.44 months. All patients reported zero postoperative infection, skin and soft tissue necrosis, and loosening/breakage of the internal fixation. Regular postoperative review revealed that all patients achieved complete bony union, as evidenced by X-ray film, at 6 months after operation. Knee function (HSS) scores averaged 86.72 points at 1 year after operation; 15 people with 85 points or more, 2 people with 70-84 points, and one with 68 points. The excellent rate, according to HSS was 90%. Conclusions: Complex tibial plateau fractures with extensive soft tissue damage can be effectively remedied with a staged treatment, wherein a lateral column reconstruction is performed using a large iliac bone.

BACKGROUND Clinical femoral neck fracture is common. Based on patient age and fracture type, different surgical methods can be selected, including cannulated screw fixation of the femoral neck and artificial total hip joint or semi-hip joint replacement. When patients with femoral neck fracture are treated with cannulated screw fixation, a cannulated screw may be positioned too deep. The excessively deep-placed screw is difficult to remove and causes major trauma to the patient. CASE SUMMARY A patient with poliomyelitis and femoral neck fracture was treated with a cannulated screw that was placed too deep. A self-made auxiliary tool (made of a steel sternal wire) was used to remove the cannulated screw near the pelvic cavity. CONCLUSION The depth of the cannulated screw can be estimated before screw placement using an improved hollow screwdriver with a scale mark, thus improving the safety of screw placement and facilitating clinical use.

Background: To investigate wound healing in 402 calcaneus fracture cases using precise extensive L-shaped incision. Method: We retrospectively analyzed 402 calcaneus fracture cases, involving patients who underwent heel bone reduction and internal fixation, using precise extensive L-shaped incision, at the second hospital of Shanxi medical university between January 2018 and December 2020. Postoperative would healing was evaluated using a self-designed skin margin grading system. Results: The patients experienced osseous healing after the surgery. A Maryland foot score of ≥90% was considered excellent. The skin margins from Grade I, II, III injuries healed spontaneously after dressing change. However, Grade IV injuries healed after debridement or removal of internal fixation. Conclusions: The precise extensive L-shaped incision, used in this study, allowed for fewer postoperative wound complications and lower incidence of skin necrosis.

随着人口老龄化,骨质疏松症患者越发增多.骨质疏松症患者并发脊柱骨折、腰椎管狭窄症、腰椎管滑脱、骨质疏松性椎体骨折不愈合(Kummel)病等需行手术治疗[1].但骨质疏松症患者存在骨量少,内固定易拔出、固定易失效的棘手问题[2].骨水泥灌注螺钉可减少上述并发症[3-6].我院精准化使用自行研制脊柱骨水泥灌注螺钉取得良好疗效.报告如下.

Background: Management of Rüedi-Allgöwer III or AO/OTA type C3 pilon fracture presents numerous challenges to the orthopaedic surgeon. A joint preservation technique using a large autologous ilium with periosteum in combination with internal implant fixation was reported to improve the outcome of reconstruction . Methods: Twenty-five patients according to Tscherne/Oestern FxCO-I closed fracture and FxOI open fractures classification after Rüedi-Allgöwer III or AO/OTA type C3 pilon fracture received a large autologous ilium with periosteum for tibiotalar joint reconstruction and open reduction and internal fixation (ORIF), between March 2015 and September 2018. The visual analog scale (VAS), American Orthopaedic Foot & Ankle Society (AOFAS) score, and Burwell and Charnley criteria were used for outcome analysis. Results: Twenty patients with an average age of 45.2 years were followed for an average of 18.3 months. The VAS and AOFAS scores, and Burwell and Charnley ratings were recorded at the last follow-up after reconstructive surgery. Two patients developed redness and swelling at the wound site, but recovered after local care and dressing changes. No patient displayed deep surgical site infection, donor site complication, non-union or local complication during the final follow-up. The average bone union time was 18.3 months (range 3-36). Conclusions: Large autologous ilium with periosteum in combination with ORIF can be performed for tibiotalar joint reconstruction. This experimental procedure reduces the risk of post-operative complications following articular reconstruction for Rüedi-Allgöwer III or AO/OTA type C3 pilon fractures in short follow-up. Level of Evidence: Level III, retrospective cohort study

由于骨生物学的长足发展,人们逐渐认识到骨形成不单单是骨骼系统的行为,而是需要凝血系统、免疫系统等多系统同时参与的病理生理过程.对于局部的微环境来说,尤其是局部免疫微环境,在成骨过程中具有重要调控作用.基于这一研究背景,遂有学者提出基于"骨免疫微环境"的研发调控理念[1],研发的特殊材料可以通过调控免疫细胞反应,从而诱导产生有利于骨生成的骨免疫微环境,进一步协调成骨与破骨过程,进而达到最佳的骨再生效果[2].所以就免疫微环境与骨代谢的联系,以及基于免疫微环境调控的骨生物材料研发进展进行综述.

Background: Management of Rüedi-Allgöwer III or AO type C3 pilon fracture present numerous challenges to the orthopaedic surgeon. A joint preservation technique using a large autologous ilium with periosteum in combination with internal implant fixation was reported to improve the outcome of reconstruction. Methods: Twenty-five patients with soft tissue injury of Tscherne-Gotzen I-II after Rüedi-Allgöwer III pilon fracture received a large autologous ilium with periosteum for tibiotalar joint reconstruction and open reduction and internal fixation (ORIF), between March 2015 and September 2018. The visual analog scale (VAS), American Orthopaedic Foot & Ankle Society (AOFAS) score, and Burwell and Charnley criteria were used for outcome analysis.Results: Twenty patients with an average age of 45.2 years were followed for an average of 18.3 months. The VAS and AOFAS scores, and Burwell and Charnley ratings were recorded at the last follow-up after reconstructive surgery. Two patients developed redness and swelling at the wound site, but recovered after local care and dressing changes. No patient displayed deep surgical site infection, donor site complication, non-union or local complication during the final follow-up. The average bone union time was 18.3 months (range 3-36).Conclusions: Large autologous ilium with periosteum in combination with ORIF can be safely performed for tibiotalar joint reconstruction. This method greatly reduces the risk of post-operative complications following articular reconstruction for Rüedi-Allgöwer III pilon fractures.Level of Evidence: Level III, retrospective cohort study

The objective was to analyze the long-term clinical outcome of terrible triad injury of the elbow following surgical intervention with a single lateral approach. We treated twenty-five patients with terrible triad injury of the elbow from July 1, 2017, to June 30, 2020, and performed post hoc analysis. All patients underwent standardized surgery which entailed: plate fixation for the ulnar coronoid process, fixation or replacement of the radial head, and repair of the lateral ligament but not the medial collateral ligament. We followed up each patient for an average of 22.9 months (range, 12 to 36 months) after surgery. Patients had an average angle scope of elbow flexion and extension that ranged from 8° to 120°. Average pronation of the elbow was 75° (range, 10°–85°), and average supination was 72° (range, 25°–80°). Patient-reported outcome measures were excellent: the DASH and Mayo elbow performance score (MEPS) were 96%. We were unable to follow-up one patient (4%). Among the remaining 24 patients, one patient (4%) presented with heterotopic ossification and stiffness following arthrolysis in the elbow one year after the initial surgery. We did not observe any joint dislocation, subluxation, or joint instability in the elbow after surgery. The single lateral approach, a sequential surgery for terrible triad injury of the elbow, can improve initial stability of the elbow. Patients are able to perform rehabilitative exercises sooner in their recovery, which helps to reduce stiffness. Heterotopic ossification is also reduced.

Objective To reviewe the effect of medial patellofemoral ligament reconstruction and vastus medi-alis obliquus anterior transposition in the treatment of recurrent patellar dislocation in the past three years. Methods Thirty-four patients were followed up for an average of 24.5 months. The Kujala score and Lysholm score were record-ed at the baseline and during the follow-up after the operation. CT was used to measure the Tibial Tuberosity-Trochlear Groove (TT-TG) distance, patellar congruence angle, patellar tilt angle and lateral patellofemoral angle at the baseline and during the follow-up after the operation. Results The findings showed that the postoperative Kujala score and Lysholm score were significantly improved compared with those at the baseline ( P<0.05), whereas there were statistically significant differences in the TT-TG value, patellar congruence angle, patellar tilt angle and lateral patellofemoral angle compared with those at the baseline (P<0.05). Conclusion Medial patellofemoral ligament re-construction and vastus medialis obliquus anterior transposition can simultaneously recover static and dynamic stabili-ty of patella. It is a good way to treat recurrent patellar dislocation.