We present one case of bone-Langerhans' cell histiocytosis in a three-year-old male child presenting osseous lesions in the skull and the femur, which are very frequent localisations in histiocytosis. Bone scintigraphy is useful for both initial staging and follow-up associated with other imaging modalities. (c) 2008 Elsevier Masson SAS. All rights reserved.