A new compound, Bentyl hydrochloride (β-diethylaminoethyl 1-cyclohexylcyclo-hexanecarboxylate hydrochloride), has been demonstrated to possess parasympathetic depressant properties. It has a marked relaxing action in vivo on normal and barium-stimulated intestine, and it strongly antagonizes the intestinal effects of acetylcholine. The bulk of Bentyl administered to animals appears to be destroyed in the body, and the substance has low toxicity following single and repeated administration to animals.

Experiments in rats and dogs, employing various dosage regimes, demonstrate urinary elimination accounts for roughly only 10 to 30 per cent of administered Decapryn Succinate. The antihistamine does not accumulate in various body tissues, and it is concluded that the bulk of administered Decapryn Succinate is destroyed in the body.