Intracellular accumulation of esterified cholesterol-containing lipid droplets,which leads to the formation of foam cells associated with related inflammatory reactions,is the core pathological event in atherosclerosis[1,2].Cardiovascular and cerebrovascular diseases caused by atherosclerosis remain the leading causes of human death and disability after decades of clinical application of highly effective lipid-lowering treatment[3,4].Clearly,lowering lipids alone or even in combination with some potential anti-inflamma-tion resolution is far from enough to prevent and treat athero-sclerosis-induced vascular disease,demanding new approaches and/or therapeutic targets for anti-atherosclerosis.

The advance of medical technology and the extended life expectancy have the elderly face more multiple problems. To cope with the aging society, the government and social welfare units should stress more on the elderly welfare, health care, and assistance in daily life. Young population migrating to cities for better job and life, female manpower largely involving in the labor market, large change in family structure, and rapidly increase in the elderly population have resulted in more situations of the elderly living alone. Aiming at the elderly in Shanghai, as the research objects, total 500 copies of questionnaire are distributed, and 364 valid copies are retrieved, with the retrieval rate 73%. The research results conclude 1. significantly negative effects of perceived health condition on medical ecology service use, 2. remarkably positive effects of social support on perceived health condition, and 3. notably negative effects of social support on medical ecology service use. According to the results, suggestions are proposed, expecting to provide reference for social affairs units promoting the inadequacy so that the elderly are able to independently take care of themselves. It would reduce national health care expenditure and enhance the elderly satisfaction with life.

To analyze stroke patients' and the caregivers' satisfaction with environmental management as well as the mutual influence mechanism. General hospitals and community medical institutions in Shanghai City were randomly sampled 600 pairs of stroke inpatients and the caregivers for the questionnaire survey during January - June, 2016, and 575 pairs were eventually received. The "Actor-Partner Interdependence" model (APIM) was constructed to study the mutual influence of two interdependence variables on the satisfaction with environmental management. Patients' age and caregivers' education level showed significant effects on patients' and the caregivers' satisfaction with environmental management (influence coefficients [beta=-0.10 and [3=0.08, respectively). In other words, the higher patients' age and the lower caregivers' education level revealed the lower satisfaction with environmental management. Patients' self-care degree at admission presented remarkably positive effects on their and the caregivers' satisfaction with environmental management (influence coefficients [beta=0.11 and [beta=0.07, respectively). In other words, the higher patients' self-care at admission would enhance the satisfaction with environmental management and caregivers' satisfaction with environmental management. Besides, the influence coefficient of the former was higher than it of the latter (beta=0.11>beta=0.07). Patients' length of stays merely appeared notably negative effects on the satisfaction with environmental management (influence coefficient [beta=-0.02). Both patients' and the caregivers' satisfaction with inpatient service showed significantly negative effects on the satisfaction with environmental management (beta=-0.33 and [beta=-0.16, respectively). In this case, the higher patients' and the caregivers' satisfaction with inpatient service appeared the higher satisfaction with environmental management. Besides, the influence coefficient of the former is higher than it of the latter (beta=0.33>beta=0.16). Medical staff and health decision makers could apply correspondent measures, enhance individual satisfaction with inpatient service by taking the combination of individual characteristics and disease characteristics of the two into account, and eventually promote stroke patients' satisfaction with environmental management.